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The map label for this gene is aroA

Identifier: 222523361

GI number: 222523361

Start: 66885

End: 68192

Strand: Direct

Name: aroA

Synonym: Chy400_0062

Alternate gene names: 222523361

Gene position: 66885-68192 (Clockwise)

Preceding gene: 222523360

Following gene: 222523362

Centisome position: 1.27

GC content: 57.57

Gene sequence:

>1308_bases
ATGAAAGGTATAACGCTAACCGCCCCTAAGCGATTGCGCGGTGTGATCGAGGTACCGGGCGATAAGTCGATTTCGCATCG
GTCAGTGTTGTTCAATGCCATCGCTACGGGCAGTGCCCACATCACCCATTTCCTGCCTGGCGCTGATTGTCTCTCGACGG
TTGCGTGTATCCGGGCATTAGGCGTGACGGTAGAACAACCCGCCGAACGCGAGTTGATCGTCCATGGTGTCGGGTTAGGT
GGCTTACGAGAACCGGCTGACGTGCTTGATTGTGGAAATTCCGGTACCACCCTGCGCCTGCTGGCCGGCTTGCTGGCGGG
CCATCCGTTTTTCAGTGTCTTGACCGGTGATGCCTCATTGCGTTCACGGCCACAACGCCGAATCGTCGTCCCGTTGCGGG
CAATGGGTGCGCAGATCGATGGCCGTGACGATGGTGATCGGGCACCACTGGCGATTCGAGGTAACCGACTGCGTGGTGGC
CATTATGAGTTGTCAATTGCTTCAGCACAGGTGAAATCAGCGTTGTTACTGGCAGCGTTGAATGCTGAACAACCCTTAAC
ACTGACCGGACGCATAGATTCGCGTGATCATACCGAACGTATGCTGGCAGCAATGGGGTTGGAGATTACCGTTACTGCGG
ATCAGATCACGATCCAGCCACCATCAGAGGCAACTGCCCCCACTGCGCTCTCGCTGCGTGTCCCCGGCGATCCCTCATCA
GCAGCATTCTGGTGGGTAGCGGCTGCCATCCATCCCGATGCTGAACTGGTGACGCCCGGCGTTTGCCTGAATCCGACCCG
GATTGGGGCGATAGAGGTTTTGCAAGCGATGGGGGCCGACCTTACTGTTATGAATGAACGACTGGAAGGAAGCGAACCGG
TCGGCGATGTTGTTGTGCGTTCTTCATCACTGCGCGGCACAACGATTGCGGGTACGTTGATTCCGCGCTTAATCGATGAA
ATTCCCGTGCTGGCAGTTGCTGCGGCCTGTGCTAGTGGTGAAACAGTGATTCGTGATGCGCAGGAGCTACGGGCCAAAGA
AACCGACCGCATCGCGACGGTGGCTGCCGGCCTGAGTGCAATGGGCGCAGTCGTTGAACCAACCGCTGATGGTATGGTGA
TTGTCGGGCAGCCGGGGCAACTCCAGGGTACGACACTCAATAGTTTTCATGACCACCGGCTGGCAATGGCCTGGGCGATT
GCCGCAATGGTAGCTCGTGGTGAGACAACGATTCTTGAACCGGCTGCGGCTGCGGTAAGCTATCCCGAATTCTGGCAGAC
GCTGGCTATGGTACAGGAGGCCGCATGA

Upstream 100 bases:

>100_bases
AAGGTATCTGATTACCCAGCGCGGTTTTGGTTATAAGCTAATTGTAGCGCCTGAACTTGAGTCATAAGCGTGAGTTGTCA
GACTGGAGTGGAATCACGTA

Downstream 100 bases:

>100_bases
ACGATGGCTTTACCTTTACCGTTGAGATCTTCACACCAACGCTGCTCTGTACTGGTAGTTACACGCTTCCAATGTACCGT
AGAGTCAGCGATGCGCTCAA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKGITLTAPKRLRGVIEVPGDKSISHRSVLFNAIATGSAHITHFLPGADCLSTVACIRALGVTVEQPAERELIVHGVGLG
GLREPADVLDCGNSGTTLRLLAGLLAGHPFFSVLTGDASLRSRPQRRIVVPLRAMGAQIDGRDDGDRAPLAIRGNRLRGG
HYELSIASAQVKSALLLAALNAEQPLTLTGRIDSRDHTERMLAAMGLEITVTADQITIQPPSEATAPTALSLRVPGDPSS
AAFWWVAAAIHPDAELVTPGVCLNPTRIGAIEVLQAMGADLTVMNERLEGSEPVGDVVVRSSSLRGTTIAGTLIPRLIDE
IPVLAVAAACASGETVIRDAQELRAKETDRIATVAAGLSAMGAVVEPTADGMVIVGQPGQLQGTTLNSFHDHRLAMAWAI
AAMVARGETTILEPAAAAVSYPEFWQTLAMVQEAA

Sequences:

>Translated_435_residues
MKGITLTAPKRLRGVIEVPGDKSISHRSVLFNAIATGSAHITHFLPGADCLSTVACIRALGVTVEQPAERELIVHGVGLG
GLREPADVLDCGNSGTTLRLLAGLLAGHPFFSVLTGDASLRSRPQRRIVVPLRAMGAQIDGRDDGDRAPLAIRGNRLRGG
HYELSIASAQVKSALLLAALNAEQPLTLTGRIDSRDHTERMLAAMGLEITVTADQITIQPPSEATAPTALSLRVPGDPSS
AAFWWVAAAIHPDAELVTPGVCLNPTRIGAIEVLQAMGADLTVMNERLEGSEPVGDVVVRSSSLRGTTIAGTLIPRLIDE
IPVLAVAAACASGETVIRDAQELRAKETDRIATVAAGLSAMGAVVEPTADGMVIVGQPGQLQGTTLNSFHDHRLAMAWAI
AAMVARGETTILEPAAAAVSYPEFWQTLAMVQEAA
>Mature_435_residues
MKGITLTAPKRLRGVIEVPGDKSISHRSVLFNAIATGSAHITHFLPGADCLSTVACIRALGVTVEQPAERELIVHGVGLG
GLREPADVLDCGNSGTTLRLLAGLLAGHPFFSVLTGDASLRSRPQRRIVVPLRAMGAQIDGRDDGDRAPLAIRGNRLRGG
HYELSIASAQVKSALLLAALNAEQPLTLTGRIDSRDHTERMLAAMGLEITVTADQITIQPPSEATAPTALSLRVPGDPSS
AAFWWVAAAIHPDAELVTPGVCLNPTRIGAIEVLQAMGADLTVMNERLEGSEPVGDVVVRSSSLRGTTIAGTLIPRLIDE
IPVLAVAAACASGETVIRDAQELRAKETDRIATVAAGLSAMGAVVEPTADGMVIVGQPGQLQGTTLNSFHDHRLAMAWAI
AAMVARGETTILEPAAAAVSYPEFWQTLAMVQEAA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=451, Percent_Identity=30.5986696230599, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=473, Percent_Identity=26.8498942917548, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_CHLAA (A9WBA4)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001633700.1
- ProteinModelPortal:   A9WBA4
- SMR:   A9WBA4
- GeneID:   5828194
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_0057
- HOGENOM:   HBG646626
- OMA:   LSRNHTE
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45499; Mature: 45499

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGITLTAPKRLRGVIEVPGDKSISHRSVLFNAIATGSAHITHFLPGADCLSTVACIRAL
CCCCEECCCHHHCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
GVTVEQPAERELIVHGVGLGGLREPADVLDCGNSGTTLRLLAGLLAGHPFFSVLTGDASL
CCCCCCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCHHH
RSRPQRRIVVPLRAMGAQIDGRDDGDRAPLAIRGNRLRGGHYELSIASAQVKSALLLAAL
HCCCCCEEEEEHHHCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEHHHHHHHHHHHEE
NAEQPLTLTGRIDSRDHTERMLAAMGLEITVTADQITIQPPSEATAPTALSLRVPGDPSS
CCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEECEEEEECCCCCCCCCEEEEECCCCCCC
AAFWWVAAAIHPDAELVTPGVCLNPTRIGAIEVLQAMGADLTVMNERLEGSEPVGDVVVR
CEEEEEEEEECCCHHHCCCCEEECCCCCCHHHHHHHCCCCEEEEHHHCCCCCCCCHHEEE
SSSLRGTTIAGTLIPRLIDEIPVLAVAAACASGETVIRDAQELRAKETDRIATVAAGLSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGAVVEPTADGMVIVGQPGQLQGTTLNSFHDHRLAMAWAIAAMVARGETTILEPAAAAVS
HCCEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHHCC
YPEFWQTLAMVQEAA
CHHHHHHHHHHHHCC
>Mature Secondary Structure
MKGITLTAPKRLRGVIEVPGDKSISHRSVLFNAIATGSAHITHFLPGADCLSTVACIRAL
CCCCEECCCHHHCEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
GVTVEQPAERELIVHGVGLGGLREPADVLDCGNSGTTLRLLAGLLAGHPFFSVLTGDASL
CCCCCCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCHHH
RSRPQRRIVVPLRAMGAQIDGRDDGDRAPLAIRGNRLRGGHYELSIASAQVKSALLLAAL
HCCCCCEEEEEHHHCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEHHHHHHHHHHHEE
NAEQPLTLTGRIDSRDHTERMLAAMGLEITVTADQITIQPPSEATAPTALSLRVPGDPSS
CCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEECEEEEECCCCCCCCCEEEEECCCCCCC
AAFWWVAAAIHPDAELVTPGVCLNPTRIGAIEVLQAMGADLTVMNERLEGSEPVGDVVVR
CEEEEEEEEECCCHHHCCCCEEECCCCCCHHHHHHHCCCCEEEEHHHCCCCCCCCHHEEE
SSSLRGTTIAGTLIPRLIDEIPVLAVAAACASGETVIRDAQELRAKETDRIATVAAGLSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGAVVEPTADGMVIVGQPGQLQGTTLNSFHDHRLAMAWAIAAMVARGETTILEPAAAAVS
HCCEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCHHHHCC
YPEFWQTLAMVQEAA
CHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA