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The map label for this gene is yhfP [H]

Identifier: 222094535

GI number: 222094535

Start: 855614

End: 856612

Strand: Direct

Name: yhfP [H]

Synonym: BCQ_0873

Alternate gene names: 222094535

Gene position: 855614-856612 (Clockwise)

Preceding gene: 222094532

Following gene: 222094538

Centisome position: 16.41

GC content: 40.94

Gene sequence:

>999_bases
ATGAATCATACATCATTCCGAGCAATTGTTGTGAACGAAACAGAAAGTAAGCGGTTTGTAAGAAACGTTGTAGCGAGAGA
AGTAAGTAGTTTACCTGAAGGGGACGTATTCATACAGGTTCATTATTCTTCACTAAATTATAAAGACGCTCTTTCAGCCA
CTGGTAATAAAGGTGTTACGAGAACATATCCTCATACGCCAGGAATTGATGCAGCAGGAGTGGTTGTGAGTAGTAAAGAT
GCTACCATTAAGGCGGGAGATCAAGTCATTGTAACGGGATATGATTTAGGGATGAATACTTCTGGTGGTTTCGGAGAATA
TATTCGCGTGCCGGCATCTTGGATTGTCCCTTTACCAGAGGGAATGTCATTAAAGGAAAGTATGATGTACGGGACGGCAG
GTTTTACAGCCGCTTTATCAGTATATAAGCTTATTAGAGCAGGGGTAACGCCTAGTATGGGCGATGTTTTAGTAACGGGT
GCTACAGGCGGCGTAGGAAGTGTAGCTGTTAGTATTTTAAGTAAGTTAGGGTTTAGCGTAGTAGGAGCGACAGGAAAAAT
GGAAGAGGAACAGATGCTACTACGTCTAGGAGCGAAAAAGGTGATTCATCGCGCAGAATTGAATGATGAATCAGGAAGAC
CAATGCTTAAAGGAATATACGCCGGAGTTATCGATACTGTAGGTGGGCATATGTTAGAAACAGTTTTAAAAACGGTAAAG
TATGGCGGGTGCATAACGACATGCGGTAATGTGGCAGGCCATGAATTACAAACAACGGTATATCCGTTTATTTTGCGAGG
CATAAGCCTGTTAGGAGTAGATTCTGTACAGTGCCCAGTAGATGTGAGAAGAGATGTATGGACGCTCCTAGCAAATGAAT
GGGAAAACAAAGAGTTACTATCTTATACAGAAGAATGTACATTAGAAGAATTAGATGAGAAGTTTACACTTATATTGCAA
GGAAAGTTAAAAGGTAGAACGGTTGTAAATATGAAATGA

Upstream 100 bases:

>100_bases
GAAGTAAGATTTGTTGAAATATAGCCAAGAAGAAACGAGTAGGTTTACTTATTTCTTCTATATAATAAAGAAGAAATTTA
CGGATAAAGGAGAGAGCATA

Downstream 100 bases:

>100_bases
AAAAAGAGACGCTCATGTTAGCGTCTCTTTCTTATTATAATGATTGTTTTAAATTGACTTTACCTTGTTCACCTAAAACA
CCATCAGCGATATTTACAGC

Product: alcohol dehydrogenase, zinc containing

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNHTSFRAIVVNETESKRFVRNVVAREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVTRTYPHTPGIDAAGVVVSSKD
ATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPASWIVPLPEGMSLKESMMYGTAGFTAALSVYKLIRAGVTPSMGDVLVTG
ATGGVGSVAVSILSKLGFSVVGATGKMEEEQMLLRLGAKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETVLKTVK
YGGCITTCGNVAGHELQTTVYPFILRGISLLGVDSVQCPVDVRRDVWTLLANEWENKELLSYTEECTLEELDEKFTLILQ
GKLKGRTVVNMK

Sequences:

>Translated_332_residues
MNHTSFRAIVVNETESKRFVRNVVAREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVTRTYPHTPGIDAAGVVVSSKD
ATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPASWIVPLPEGMSLKESMMYGTAGFTAALSVYKLIRAGVTPSMGDVLVTG
ATGGVGSVAVSILSKLGFSVVGATGKMEEEQMLLRLGAKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETVLKTVK
YGGCITTCGNVAGHELQTTVYPFILRGISLLGVDSVQCPVDVRRDVWTLLANEWENKELLSYTEECTLEELDEKFTLILQ
GKLKGRTVVNMK
>Mature_332_residues
MNHTSFRAIVVNETESKRFVRNVVAREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVTRTYPHTPGIDAAGVVVSSKD
ATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPASWIVPLPEGMSLKESMMYGTAGFTAALSVYKLIRAGVTPSMGDVLVTG
ATGGVGSVAVSILSKLGFSVVGATGKMEEEQMLLRLGAKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETVLKTVK
YGGCITTCGNVAGHELQTTVYPFILRGISLLGVDSVQCPVDVRRDVWTLLANEWENKELLSYTEECTLEELDEKFTLILQ
GKLKGRTVVNMK

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239676, Length=176, Percent_Identity=31.25, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI194239674, Length=176, Percent_Identity=31.25, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI13236495, Length=176, Percent_Identity=31.25, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1789651, Length=320, Percent_Identity=42.8125, Blast_Score=265, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 35703; Mature: 35703

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHTSFRAIVVNETESKRFVRNVVAREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVT
CCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCCCCE
RTYPHTPGIDAAGVVVSSKDATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPASWIVPLPE
ECCCCCCCCCCCCEEEECCCCEEECCCEEEEEEEECCCCCCCCCCCEEECCCCEEEECCC
GMSLKESMMYGTAGFTAALSVYKLIRAGVTPSMGDVLVTGATGGVGSVAVSILSKLGFSV
CCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCEE
VGATGKMEEEQMLLRLGAKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETVLKTVK
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGGCITTCGNVAGHELQTTVYPFILRGISLLGVDSVQCPVDVRRDVWTLLANEWENKELL
CCCEEECCCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHH
SYTEECTLEELDEKFTLILQGKLKGRTVVNMK
HHHHHCCHHHHCCEEEEEEEECCCCCEEEECC
>Mature Secondary Structure
MNHTSFRAIVVNETESKRFVRNVVAREVSSLPEGDVFIQVHYSSLNYKDALSATGNKGVT
CCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCCCCCE
RTYPHTPGIDAAGVVVSSKDATIKAGDQVIVTGYDLGMNTSGGFGEYIRVPASWIVPLPE
ECCCCCCCCCCCCEEEECCCCEEECCCEEEEEEEECCCCCCCCCCCEEECCCCEEEECCC
GMSLKESMMYGTAGFTAALSVYKLIRAGVTPSMGDVLVTGATGGVGSVAVSILSKLGFSV
CCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCEE
VGATGKMEEEQMLLRLGAKKVIHRAELNDESGRPMLKGIYAGVIDTVGGHMLETVLKTVK
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGGCITTCGNVAGHELQTTVYPFILRGISLLGVDSVQCPVDVRRDVWTLLANEWENKELL
CCCEEECCCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHH
SYTEECTLEELDEKFTLILQGKLKGRTVVNMK
HHHHHCCHHHHCCEEEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]