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The map label for this gene is dnaX [H]

Identifier: 221633732

GI number: 221633732

Start: 1764490

End: 1766178

Strand: Reverse

Name: dnaX [H]

Synonym: trd_1759

Alternate gene names: 221633732

Gene position: 1766178-1764490 (Counterclockwise)

Preceding gene: 221633736

Following gene: 221633731

Centisome position: 88.18

GC content: 66.79

Gene sequence:

>1689_bases
ATGCAGTCCGGCTCATTGTACCGGAAATATCGCCCGCAGACCTTCGAGGAACTGGTTGGACAGGAAGCCATCGCGCGCAC
GCTGCGCAATGCGGTCGCCCTCGACCGGGTGGCGCACGCCTACCTGTTTTGTGGGCCGCGCGGTACCGGGAAAACCAGCA
CGGCGCGCCTGCTGGCCAAGGCGGTCAACTGCCGGGACGCCGATCCCTGGCGGCGCCCCTGCAACCAGTGCGGAGCCTGC
CGCTCCATCGCCACTGGTACAGCGGTCGATATCATCGAGATCGACGCGGCTTCCAACCGTGGAGTCGACGATATCCGCGA
TCTCCGCGAGAAGGTGAAGTATGCACCCGTCGAGCTGCGCACCAAGTTCTATATCATCGACGAAGCGCACCAATTGACAC
GTGACGCCTTCAACGCCTTCCTCAAGACGCTGGAGGAGCCACCCCCGCACGTCGTCTTCGTCCTGGCGACGACCGAGCCG
GACAAACTTCCGGAAACGGTTGCCTCACGCTGCCAGCGCTTCGATTTCCGCCGCTTGCCCGTTGACCGGATGGTCGAGCG
CCTCCGTTTCGTGTGCCTGCGCGAAGGCATCGAGGCACCGGACGACGTGCTCGCCCTGATCGCTCGCCGCGCTGCGGGGA
GCCTGCGCGATGCCCTCGGCCTCCTCGAGCGACTCGCCGTTTTCGCGAGCGACGGCGAGAACGAACCAGTCATCACGCTC
GAGCTGGCGCGCCAGGTCCTGGGTGGCAGCCGCGACGATCGGCTTCTCGATCTCGTGACGGCGATCGCTGACCGGGATGC
TGGCCGGGCTCTCCGGCTGGTGGCAGAGGCGGCCGATGCGGGCGATGACCTGCACCAGCTCGGTCGCGAGCTGGTCCGTT
TCACTCGGACACTGTTGTACGTCCGGGCTGGTGGCAGCGATCCGCTCCTGCCGCCCGAGGCATCAGCGCTGGCTCAGCGC
TTCTCGCTCGAGGAACTCGCGCTCGTTCTCCGTCGGCTGACCGGTCTCGACGCGCCCCTCCCGCGATCCGGCATCGATCC
GCAGCTCCTCCTGGAACTCGGCCTCGTGGAGTCGATCCTGTTGCTCGATGGATCGCAGCGCGAGCGCACTCTTGCACCTT
CTGGTGCCACGGCGGTACCGGCGATGACCGCAACACCGCCGCGCGTTGTCCCAGCGGCTCCACGCCCGGCTCCCCCGCCA
GCAGCATCGTCCCAGCCGGCCGTTTCGCCGACGACCAGTCCAGCGGTCGATGGGGACGATGAGCTCCTCGATCAGCTGCT
CACGCGCTGGGCTGCGATCCGGCGCGAGCTCCGGGCTGTCAACAGCAAGGCGGCTGCACTCCTGGCGGATGCTGAACCAC
GCCTGATCCGCGGAGATGAGGTCGTCCTCGTCGCGCCGTACGAGTTCCATCGTCGCCGTATCAACGAAGAGGCCGAGCTG
CGACGTGTGATCGAACGGGTGCTGGCCAAGCATCTCGGCCGAGCCTGCCGCATCACCTGTCTCGCGCCGGAAGACGTGCC
CCGGCAGCTGACCACAGCGGCCGGGGAGCCGCTTTCTTCGGAAGACGAAACTGACCCAAAAGGTCGGCTGACGCCTGATT
CCTCCGGACAACAGCGACCGGTCGCGCTGACTCCGGAGGACCAGCGCCGCCTGGAGGCAGCCAAGGCGATCTTCGAGGCA
GTCGAGTAA

Upstream 100 bases:

>100_bases
CCCGGCTGGCACGTCCCCACGTATGCTTAGTCGTACGGACGCTCGTGACGCGTCACCACACGGAGAGGCCCCAAGGATGG
ACTCGTCCCGCGAGGCCAGG

Downstream 100 bases:

>100_bases
CCCTTACGGTCCTTTGCGGCGGCTGCAGCGGTCCCAGCGAGAAAGGAGAGAGCCATGAGCGTGGCCCGTTTCCCGCACGG
TTTCCTCTGGGGTACCGCGA

Product: DNA polymerase III subunit gamma/tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MQSGSLYRKYRPQTFEELVGQEAIARTLRNAVALDRVAHAYLFCGPRGTGKTSTARLLAKAVNCRDADPWRRPCNQCGAC
RSIATGTAVDIIEIDAASNRGVDDIRDLREKVKYAPVELRTKFYIIDEAHQLTRDAFNAFLKTLEEPPPHVVFVLATTEP
DKLPETVASRCQRFDFRRLPVDRMVERLRFVCLREGIEAPDDVLALIARRAAGSLRDALGLLERLAVFASDGENEPVITL
ELARQVLGGSRDDRLLDLVTAIADRDAGRALRLVAEAADAGDDLHQLGRELVRFTRTLLYVRAGGSDPLLPPEASALAQR
FSLEELALVLRRLTGLDAPLPRSGIDPQLLLELGLVESILLLDGSQRERTLAPSGATAVPAMTATPPRVVPAAPRPAPPP
AASSQPAVSPTTSPAVDGDDELLDQLLTRWAAIRRELRAVNSKAAALLADAEPRLIRGDEVVLVAPYEFHRRRINEEAEL
RRVIERVLAKHLGRACRITCLAPEDVPRQLTTAAGEPLSSEDETDPKGRLTPDSSGQQRPVALTPEDQRRLEAAKAIFEA
VE

Sequences:

>Translated_562_residues
MQSGSLYRKYRPQTFEELVGQEAIARTLRNAVALDRVAHAYLFCGPRGTGKTSTARLLAKAVNCRDADPWRRPCNQCGAC
RSIATGTAVDIIEIDAASNRGVDDIRDLREKVKYAPVELRTKFYIIDEAHQLTRDAFNAFLKTLEEPPPHVVFVLATTEP
DKLPETVASRCQRFDFRRLPVDRMVERLRFVCLREGIEAPDDVLALIARRAAGSLRDALGLLERLAVFASDGENEPVITL
ELARQVLGGSRDDRLLDLVTAIADRDAGRALRLVAEAADAGDDLHQLGRELVRFTRTLLYVRAGGSDPLLPPEASALAQR
FSLEELALVLRRLTGLDAPLPRSGIDPQLLLELGLVESILLLDGSQRERTLAPSGATAVPAMTATPPRVVPAAPRPAPPP
AASSQPAVSPTTSPAVDGDDELLDQLLTRWAAIRRELRAVNSKAAALLADAEPRLIRGDEVVLVAPYEFHRRRINEEAEL
RRVIERVLAKHLGRACRITCLAPEDVPRQLTTAAGEPLSSEDETDPKGRLTPDSSGQQRPVALTPEDQRRLEAAKAIFEA
VE
>Mature_562_residues
MQSGSLYRKYRPQTFEELVGQEAIARTLRNAVALDRVAHAYLFCGPRGTGKTSTARLLAKAVNCRDADPWRRPCNQCGAC
RSIATGTAVDIIEIDAASNRGVDDIRDLREKVKYAPVELRTKFYIIDEAHQLTRDAFNAFLKTLEEPPPHVVFVLATTEP
DKLPETVASRCQRFDFRRLPVDRMVERLRFVCLREGIEAPDDVLALIARRAAGSLRDALGLLERLAVFASDGENEPVITL
ELARQVLGGSRDDRLLDLVTAIADRDAGRALRLVAEAADAGDDLHQLGRELVRFTRTLLYVRAGGSDPLLPPEASALAQR
FSLEELALVLRRLTGLDAPLPRSGIDPQLLLELGLVESILLLDGSQRERTLAPSGATAVPAMTATPPRVVPAAPRPAPPP
AASSQPAVSPTTSPAVDGDDELLDQLLTRWAAIRRELRAVNSKAAALLADAEPRLIRGDEVVLVAPYEFHRRRINEEAEL
RRVIERVLAKHLGRACRITCLAPEDVPRQLTTAAGEPLSSEDETDPKGRLTPDSSGQQRPVALTPEDQRRLEAAKAIFEA
VE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=291, Percent_Identity=27.8350515463918, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI194306571, Length=294, Percent_Identity=27.5510204081633, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI194306567, Length=294, Percent_Identity=27.5510204081633, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI31563534, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4506491, Length=244, Percent_Identity=27.8688524590164, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI31881687, Length=244, Percent_Identity=27.8688524590164, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786676, Length=302, Percent_Identity=45.0331125827815, Blast_Score=248, Evalue=6e-67,
Organism=Caenorhabditis elegans, GI17554730, Length=234, Percent_Identity=29.0598290598291, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71986063, Length=243, Percent_Identity=28.3950617283951, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17541988, Length=293, Percent_Identity=23.8907849829352, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322528, Length=291, Percent_Identity=28.1786941580756, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324478, Length=219, Percent_Identity=26.9406392694064, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI18859927, Length=296, Percent_Identity=25.6756756756757, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19921076, Length=233, Percent_Identity=29.1845493562232, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17647857, Length=277, Percent_Identity=27.0758122743682, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 61585; Mature: 61585

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSGSLYRKYRPQTFEELVGQEAIARTLRNAVALDRVAHAYLFCGPRGTGKTSTARLLAK
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
AVNCRDADPWRRPCNQCGACRSIATGTAVDIIEIDAASNRGVDDIRDLREKVKYAPVELR
HHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEC
TKFYIIDEAHQLTRDAFNAFLKTLEEPPPHVVFVLATTEPDKLPETVASRCQRFDFRRLP
EEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCC
VDRMVERLRFVCLREGIEAPDDVLALIARRAAGSLRDALGLLERLAVFASDGENEPVITL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEH
ELARQVLGGSRDDRLLDLVTAIADRDAGRALRLVAEAADAGDDLHQLGRELVRFTRTLLY
HHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VRAGGSDPLLPPEASALAQRFSLEELALVLRRLTGLDAPLPRSGIDPQLLLELGLVESIL
EECCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LLDGSQRERTLAPSGATAVPAMTATPPRVVPAAPRPAPPPAASSQPAVSPTTSPAVDGDD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
ELLDQLLTRWAAIRRELRAVNSKAAALLADAEPRLIRGDEVVLVAPYEFHRRRINEEAEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEECCCCEEEECCHHHHHHHCCHHHHH
RRVIERVLAKHLGRACRITCLAPEDVPRQLTTAAGEPLSSEDETDPKGRLTPDSSGQQRP
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
VALTPEDQRRLEAAKAIFEAVE
EECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQSGSLYRKYRPQTFEELVGQEAIARTLRNAVALDRVAHAYLFCGPRGTGKTSTARLLAK
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHH
AVNCRDADPWRRPCNQCGACRSIATGTAVDIIEIDAASNRGVDDIRDLREKVKYAPVELR
HHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEC
TKFYIIDEAHQLTRDAFNAFLKTLEEPPPHVVFVLATTEPDKLPETVASRCQRFDFRRLP
EEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCC
VDRMVERLRFVCLREGIEAPDDVLALIARRAAGSLRDALGLLERLAVFASDGENEPVITL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEH
ELARQVLGGSRDDRLLDLVTAIADRDAGRALRLVAEAADAGDDLHQLGRELVRFTRTLLY
HHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VRAGGSDPLLPPEASALAQRFSLEELALVLRRLTGLDAPLPRSGIDPQLLLELGLVESIL
EECCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LLDGSQRERTLAPSGATAVPAMTATPPRVVPAAPRPAPPPAASSQPAVSPTTSPAVDGDD
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
ELLDQLLTRWAAIRRELRAVNSKAAALLADAEPRLIRGDEVVLVAPYEFHRRRINEEAEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEECCCCEEEECCHHHHHHHCCHHHHH
RRVIERVLAKHLGRACRITCLAPEDVPRQLTTAAGEPLSSEDETDPKGRLTPDSSGQQRP
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
VALTPEDQRRLEAAKAIFEAVE
EECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]