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The map label for this gene is glpG [H]

Identifier: 22127769

GI number: 22127769

Start: 4352559

End: 4353395

Strand: Reverse

Name: glpG [H]

Synonym: y3898

Alternate gene names: 22127769

Gene position: 4353395-4352559 (Counterclockwise)

Preceding gene: 161484729

Following gene: 22127768

Centisome position: 94.62

GC content: 50.3

Gene sequence:

>837_bases
ATGACTCGAGTGATAGTAATCTCTAACCTACGTCTGGCGCAGGCCTTTGTGGATTATATGGCCACCCACCATGTGGCATT
AGAAATCCGGCCAGACGCTCAAGGCGTTGAAATCTGGTTGGCCGATGATGAGCAACTTTCTGCCGTCCAACATGAGTTGG
AGCAATTTCTACTGGATCCACTTAATCCACGCTATCAGGCCGCCAGTTGGCAAGCTGGGAATGTGAATTCAAATCTGCCC
TATCAGCGTTTTTCTTACCTCCAAACATTACGCAGCCAGGCTGGGCCGTTAACGCTAAGCGTGATGGTGTTGTGTATTGC
CATCTATATTCTGATGCTCATTACGGGGGATATGGCGGTAATGTCCTGGCTGGCATGGCCCTATAACAGCAGCCAGTATC
TACAAATCTGGCGTTGGGTCAGCCATGCCTTCTTGCACTTTTCACTGCTGCACATCCTGTTTAACCTGATGTGGTGGTGG
TATCTGGGCGGGCAGATGGAAAAACGGCTTGGCACCAGCAAATTGCTGGTATTAACTATCGTCTCAGCCGTCTTCAGTGG
CTGGGGGCAATCACTCTTCAGCGGTGCCAACTTTGGTGGTCTATCAGGTGTGGTTTACGCCTTAATGGGCTATGTCTGGC
TGACCGGTGAACGCGCACCCGAGCGTGGTATCTCACTGCCCCGTGGCTTGATGGCTTTTTCTGTGCTCTGGCTGATAGCC
GGGTATTTCGATATTTTAGGCTTGTCGATTGCCAATGCAGCTCATGTTTCTGGTTTAATTATTGGGCTACTAATGGCATT
TTGGGATACGCGCAACAGCGCGAGAACCGTACAATAA

Upstream 100 bases:

>100_bases
TTGATGTGGTTTACAGTATTGATGGCGGTTTTGAAGCCTGGGCCAGAAGCTATCCGCAAGACATAACCAGTGAATCTCGT
TAGACGGTAAATAAAATAAT

Downstream 100 bases:

>100_bases
CTGCCTGGCCAACCAGGCGCATTAGGGGATTATCGTGAAGCAAACGCAGCGGCATGATGCGATTATTGAGCTGGTACGCC
TACAAGGTTATGTCAGCACT

Product: intramembrane serine protease GlpG

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTRVIVISNLRLAQAFVDYMATHHVALEIRPDAQGVEIWLADDEQLSAVQHELEQFLLDPLNPRYQAASWQAGNVNSNLP
YQRFSYLQTLRSQAGPLTLSVMVLCIAIYILMLITGDMAVMSWLAWPYNSSQYLQIWRWVSHAFLHFSLLHILFNLMWWW
YLGGQMEKRLGTSKLLVLTIVSAVFSGWGQSLFSGANFGGLSGVVYALMGYVWLTGERAPERGISLPRGLMAFSVLWLIA
GYFDILGLSIANAAHVSGLIIGLLMAFWDTRNSARTVQ

Sequences:

>Translated_278_residues
MTRVIVISNLRLAQAFVDYMATHHVALEIRPDAQGVEIWLADDEQLSAVQHELEQFLLDPLNPRYQAASWQAGNVNSNLP
YQRFSYLQTLRSQAGPLTLSVMVLCIAIYILMLITGDMAVMSWLAWPYNSSQYLQIWRWVSHAFLHFSLLHILFNLMWWW
YLGGQMEKRLGTSKLLVLTIVSAVFSGWGQSLFSGANFGGLSGVVYALMGYVWLTGERAPERGISLPRGLMAFSVLWLIA
GYFDILGLSIANAAHVSGLIIGLLMAFWDTRNSARTVQ
>Mature_277_residues
TRVIVISNLRLAQAFVDYMATHHVALEIRPDAQGVEIWLADDEQLSAVQHELEQFLLDPLNPRYQAASWQAGNVNSNLPY
QRFSYLQTLRSQAGPLTLSVMVLCIAIYILMLITGDMAVMSWLAWPYNSSQYLQIWRWVSHAFLHFSLLHILFNLMWWWY
LGGQMEKRLGTSKLLVLTIVSAVFSGWGQSLFSGANFGGLSGVVYALMGYVWLTGERAPERGISLPRGLMAFSVLWLIAG
YFDILGLSIANAAHVSGLIIGLLMAFWDTRNSARTVQ

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=275, Percent_Identity=53.8181818181818, Blast_Score=315, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 31306; Mature: 31175

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVIVISNLRLAQAFVDYMATHHVALEIRPDAQGVEIWLADDEQLSAVQHELEQFLLDP
CCEEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
LNPRYQAASWQAGNVNSNLPYQRFSYLQTLRSQAGPLTLSVMVLCIAIYILMLITGDMAV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHH
MSWLAWPYNSSQYLQIWRWVSHAFLHFSLLHILFNLMWWWYLGGQMEKRLGTSKLLVLTI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHH
VSAVFSGWGQSLFSGANFGGLSGVVYALMGYVWLTGERAPERGISLPRGLMAFSVLWLIA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
GYFDILGLSIANAAHVSGLIIGLLMAFWDTRNSARTVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRVIVISNLRLAQAFVDYMATHHVALEIRPDAQGVEIWLADDEQLSAVQHELEQFLLDP
CEEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
LNPRYQAASWQAGNVNSNLPYQRFSYLQTLRSQAGPLTLSVMVLCIAIYILMLITGDMAV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHH
MSWLAWPYNSSQYLQIWRWVSHAFLHFSLLHILFNLMWWWYLGGQMEKRLGTSKLLVLTI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHH
VSAVFSGWGQSLFSGANFGGLSGVVYALMGYVWLTGERAPERGISLPRGLMAFSVLWLIA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
GYFDILGLSIANAAHVSGLIIGLLMAFWDTRNSARTVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA