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The map label for this gene is lsrR [H]

Identifier: 22127636

GI number: 22127636

Start: 4188088

End: 4188768

Strand: Reverse

Name: lsrR [H]

Synonym: y3765

Alternate gene names: 22127636

Gene position: 4188768-4188088 (Counterclockwise)

Preceding gene: 22127637

Following gene: 22127635

Centisome position: 91.05

GC content: 53.16

Gene sequence:

>681_bases
TTGGCCTCCCTCAGTATCAGTAGCCGGTTGGGTATTGGTGCCGCCCATTTATTAATGGCGCTGATACAGCCACAACAACT
TTTGGCCGTTGGTTTCGGTGAGACCACCATGTGCGCCTTGCAACATTTGAGTGGCTTTATCGCATCACAGCAGGTCCGTT
TAGTCACGTTATCCGGCGGTGTCGGCTCCTATATGACGGGGATTGGTCAGTTGGATGCGGCCTGCCAGGTCAGTATCATT
CCGGCCCCGCTGCGTGCCTCAAATGCCCATGTTGCCGACACGTTTCGCCAGGAAAACAGCGTCCGAGATGTGATGCTAGC
CGCCTGCGCGGCAGATATTGCGGTCGTTGGGATCGGTTCGGTTAATCAGCAAAAAGAAGCCACAATTTTGCGTTCGGGCT
ATATCAGCGAAGGTGAGCAACTGATGTTTAGCCGTAAAGGCGCGGTTGGGGATATCCTCGGTTACTTTATCCAAGCCGAT
GGCGCGTTGGTGCCAGATATGCAGATTCATCAGGAGTTGATTGGTATTTCGTTGGCTGATTTAACCACCATCCCAACCGT
GATTGGTGTCGCAGGGGGGGTAGAAAAAGCGGATGTGATTGTCGCAGCGCTGCGGGGGAGGTATGTGAATGCGTTGGTGA
CGGATGAGGTGACGGCGCGTGCAATCATTAACTTACTTTAA

Upstream 100 bases:

>100_bases
TCTGGGGTGATAGATTAATTCGCGCTATGAAGGCTGTCTGGAACTGGAAAATACCCTGCAACAGCATTTTGGCCTGAAGC
ATATCCGCATTCTGCCGTCT

Downstream 100 bases:

>100_bases
TTGGGTGATTGGCTATTTCACTTGCCAGTTTGAGATTGGGCAGTGCTCGTGACCGTCACAGACTGTGTGTAGGCTCCGAT
CTCTGCGCGCGGTCCCACAG

Product: SorC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAACQVSII
PAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQAD
GALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTARAIINLL

Sequences:

>Translated_226_residues
MASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAACQVSII
PAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQAD
GALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTARAIINLL
>Mature_225_residues
ASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGGVGSYMTGIGQLDAACQVSIIP
APLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGSVNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQADG
ALVPDMQIHQELIGISLADLTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTARAIINLL

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=223, Percent_Identity=67.2645739910314, Blast_Score=307, Evalue=4e-85,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 23529; Mature: 23397

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGG
CCCCCCCCCCCCCHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECC
VGSYMTGIGQLDAACQVSIIPAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGS
HHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHEEEECCC
VNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQADGALVPDMQIHQELIGISLAD
CCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHH
LTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTARAIINLL
HHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASLSISSRLGIGAAHLLMALIQPQQLLAVGFGETTMCALQHLSGFIASQQVRLVTLSGG
CCCCCCCCCCCCHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECC
VGSYMTGIGQLDAACQVSIIPAPLRASNAHVADTFRQENSVRDVMLAACAADIAVVGIGS
HHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHEEEECCC
VNQQKEATILRSGYISEGEQLMFSRKGAVGDILGYFIQADGALVPDMQIHQELIGISLAD
CCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHH
LTTIPTVIGVAGGVEKADVIVAALRGRYVNALVTDEVTARAIINLL
HHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]