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The map label for this gene is gpmB [H]

Identifier: 22127598

GI number: 22127598

Start: 4138758

End: 4139405

Strand: Reverse

Name: gpmB [H]

Synonym: y3724

Alternate gene names: 22127598

Gene position: 4139405-4138758 (Counterclockwise)

Preceding gene: 22127600

Following gene: 22127596

Centisome position: 89.97

GC content: 52.62

Gene sequence:

>648_bases
ATGTTACAGGTATACCTCGTGCGTCACGGCGAAACCTTATGGAACGCGGCACGCCGTATTCAGGGCCAATCAGACAGTCC
ACTGACCGAGATTGGTATTCGTCAGGCTCACTTAGTGGCGCAGCGGGTTCGTAATCAAGGTATCACGCATATTATTAGCA
GTGACCTTGGGCGTACTCAGCAGACGGCAAAAATTATCGCCGATGCTTGCGGGCTAACAATGGTGACAGACCCTCGACTG
CGTGAGTTGAATATGGGGGTACTGGAAAACCGTCCTATTGACAGCCTAACACCTGAAGAAGAGCAATGGCGTAAGCAAAT
GGTCAACGGCACCGAGGGGGCGCGTATCCCCGAAGGCGAATCAATGACGGAGCTGGGGCGGAGGATGCATGCAGCGTTGG
ATAGCTGCCTGGAGTTACCTGCTGGCAGTAAACCGCTGTTAGTTAGCCATGGTATGGCGTTGGGGTGTTTGTTGAGCACA
TTGTTGGGGTTGCCTGCTCATGCCGAGCGGCGTTTACGTTTACGTAACTGCTCGTTATCCCGCGTTGATTATCAGGAAAG
CCCGTGGTTGGCGTCAGGTTGGGTGATTGAAAGTGCTGGCGATACCGCTCATTTAGATATGCCAGCACTTGATGAATTAC
AGCGTTAA

Upstream 100 bases:

>100_bases
GGTACATAATGAGTGTGAATATCCTTTAAAGCCTATCTAAAATAGGTTTTATCTCAGATAGGTTTTGTGCTTATTTTACG
CAGTATAACGGAAAAATGAC

Downstream 100 bases:

>100_bases
CGGCGAATTGGAATGAAATAGTCACATTTCAGCGTAGCAGGAGGCCCATCTTTCGGCCTCCCCTGCGGGTAGAAACGTTC
AATATCATAGCCACGTCTGC

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLQVYLVRHGETLWNAARRIQGQSDSPLTEIGIRQAHLVAQRVRNQGITHIISSDLGRTQQTAKIIADACGLTMVTDPRL
RELNMGVLENRPIDSLTPEEEQWRKQMVNGTEGARIPEGESMTELGRRMHAALDSCLELPAGSKPLLVSHGMALGCLLST
LLGLPAHAERRLRLRNCSLSRVDYQESPWLASGWVIESAGDTAHLDMPALDELQR

Sequences:

>Translated_215_residues
MLQVYLVRHGETLWNAARRIQGQSDSPLTEIGIRQAHLVAQRVRNQGITHIISSDLGRTQQTAKIIADACGLTMVTDPRL
RELNMGVLENRPIDSLTPEEEQWRKQMVNGTEGARIPEGESMTELGRRMHAALDSCLELPAGSKPLLVSHGMALGCLLST
LLGLPAHAERRLRLRNCSLSRVDYQESPWLASGWVIESAGDTAHLDMPALDELQR
>Mature_215_residues
MLQVYLVRHGETLWNAARRIQGQSDSPLTEIGIRQAHLVAQRVRNQGITHIISSDLGRTQQTAKIIADACGLTMVTDPRL
RELNMGVLENRPIDSLTPEEEQWRKQMVNGTEGARIPEGESMTELGRRMHAALDSCLELPAGSKPLLVSHGMALGCLLST
LLGLPAHAERRLRLRNCSLSRVDYQESPWLASGWVIESAGDTAHLDMPALDELQR

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=131, Percent_Identity=35.8778625954198, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790856, Length=215, Percent_Identity=75.3488372093023, Blast_Score=327, Evalue=4e-91,
Organism=Escherichia coli, GI1786857, Length=186, Percent_Identity=26.8817204301075, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 23830; Mature: 23830

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVYLVRHGETLWNAARRIQGQSDSPLTEIGIRQAHLVAQRVRNQGITHIISSDLGRTQ
CEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHH
QTAKIIADACGLTMVTDPRLRELNMGVLENRPIDSLTPEEEQWRKQMVNGTEGARIPEGE
HHHHHHHHHCCCEEECCCCHHHHCCCHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
SMTELGRRMHAALDSCLELPAGSKPLLVSHGMALGCLLSTLLGLPAHAERRLRLRNCSLS
CHHHHHHHHHHHHHHHHHCCCCCCCEEHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
RVDYQESPWLASGWVIESAGDTAHLDMPALDELQR
CCCCCCCCCEECCEEEECCCCCEECCCCCHHHHCC
>Mature Secondary Structure
MLQVYLVRHGETLWNAARRIQGQSDSPLTEIGIRQAHLVAQRVRNQGITHIISSDLGRTQ
CEEEEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHH
QTAKIIADACGLTMVTDPRLRELNMGVLENRPIDSLTPEEEQWRKQMVNGTEGARIPEGE
HHHHHHHHHCCCEEECCCCHHHHCCCHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
SMTELGRRMHAALDSCLELPAGSKPLLVSHGMALGCLLSTLLGLPAHAERRLRLRNCSLS
CHHHHHHHHHHHHHHHHHCCCCCCCEEHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
RVDYQESPWLASGWVIESAGDTAHLDMPALDELQR
CCCCCCCCCEECCEEEECCCCCEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA