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The map label for this gene is yrhP [H]

Identifier: 22127565

GI number: 22127565

Start: 4101167

End: 4101844

Strand: Direct

Name: yrhP [H]

Synonym: y3691

Alternate gene names: 22127565

Gene position: 4101167-4101844 (Clockwise)

Preceding gene: 22127559

Following gene: 22127570

Centisome position: 89.14

GC content: 48.97

Gene sequence:

>678_bases
ATGCAAAGAATGCTAAGTGGCGTTATTATCGCCAGATTGCTTCACTCCCATTCGGTAATTAAGATGCTTGAAACCTCGTT
ATTCGTCGCGACACTCGCGACATTGGGAATGATCTCCCCCGGACCTGATTTTTTTCTGGTGATCAAAAACGCTGCCCGCT
ATCGCCGCACTGCCGCCATGACGACGGCAGTTGGTGTGATTTTGGGTGTTGCTACGCATATGTCTTATTGCGTGGCCGGT
CTGGCGGTCGTTATCACGACCACACCATGGTTATTCAATTTGCTGAAATATGCCGGGGCCTGCTACCTGATCTGGATTGG
TATTCAAGCACTGCTGTCACGGGGAGAAAGTAAGTTTAGTATTGATAATACTGCACAGCATCCCATCTCACTCAAAGCCG
CATTTTTGCAAGGGTACCTCTGCAACTTATTGAATCCCAAAGCGACTCTTTTCTTCCTCGCCGTTTTCACGCAAATACTG
CAGATAGACTCCGGCGTAGGAGAAAAACTATGGTACGCCTCAATCATCTGGATACTGGCCGCAATTTGGTGGCCTTTGCT
GGTGATCCTGATCCAAAGCGCGCCAGTACGCCGTGGTTTAGCCAAAACACAAAAAGTGGTCGATAAAGTGTTAGGTGGCC
TGTTGATCGGCCTTGGCATCAAAGTCGCCTTGGGCTAA

Upstream 100 bases:

>100_bases
TGTGGCCGCTCGCTGTACTGTGGCGTCAAGTCAGAAAGACATAAAGACTAAATCCCGTCACTGCTAACAACAAAATGGCA
TCAGATAACCAATAAGAGTA

Downstream 100 bases:

>100_bases
CACCGCTATCACCCCCCAGAATCTCTGGTTAAATATTCCGCTATTGAGATGGCCATCTACAATGACCGTTTACTATCCAC
AATAGTGTTGGCGATAACAT

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MQRMLSGVIIARLLHSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMTTAVGVILGVATHMSYCVAG
LAVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDNTAQHPISLKAAFLQGYLCNLLNPKATLFFLAVFTQIL
QIDSGVGEKLWYASIIWILAAIWWPLLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG

Sequences:

>Translated_225_residues
MQRMLSGVIIARLLHSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMTTAVGVILGVATHMSYCVAG
LAVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDNTAQHPISLKAAFLQGYLCNLLNPKATLFFLAVFTQIL
QIDSGVGEKLWYASIIWILAAIWWPLLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG
>Mature_225_residues
MQRMLSGVIIARLLHSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAMTTAVGVILGVATHMSYCVAG
LAVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFSIDNTAQHPISLKAAFLQGYLCNLLNPKATLFFLAVFTQIL
QIDSGVGEKLWYASIIWILAAIWWPLLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=204, Percent_Identity=31.3725490196078, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786522, Length=197, Percent_Identity=30.4568527918782, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788099, Length=186, Percent_Identity=32.7956989247312, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 24453; Mature: 24453

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRMLSGVIIARLLHSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHH
TTAVGVILGVATHMSYCVAGLAVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IDNTAQHPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQIDSGVGEKLWYASIIWILA
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AIWWPLLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQRMLSGVIIARLLHSHSVIKMLETSLFVATLATLGMISPGPDFFLVIKNAARYRRTAAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHH
TTAVGVILGVATHMSYCVAGLAVVITTTPWLFNLLKYAGACYLIWIGIQALLSRGESKFS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IDNTAQHPISLKAAFLQGYLCNLLNPKATLFFLAVFTQILQIDSGVGEKLWYASIIWILA
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AIWWPLLVILIQSAPVRRGLAKTQKVVDKVLGGLLIGLGIKVALG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]