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The map label for this gene is sgrR [H]

Identifier: 22127524

GI number: 22127524

Start: 4049015

End: 4050676

Strand: Direct

Name: sgrR [H]

Synonym: y3650

Alternate gene names: 22127524

Gene position: 4049015-4050676 (Clockwise)

Preceding gene: 22127522

Following gene: 161484745

Centisome position: 88.01

GC content: 51.08

Gene sequence:

>1662_bases
ATGTCTACCTCGCGCCTGCAACAACAATTTATTCGTCTCTGGCAACGCTATAACGGACAGTCAACGGAAACCACATTGCA
GGCGCTGGCTGAAGTGCTGAATTGTTCACGCCGCCATGTACGTTCTCTGCTGGGCAAGATGCAGCACGCGGGCTGGCTCG
ATTGGCAGGCTGAAGCTGGCCGAGGAAAACGCTCACAATTGATCTTCTTGCGTTCCGGGCTGGCGCTGCAACAACAACGG
GCTGAAGAGTTGCTGGAGCAGGATCATATTGATCAGTTAGTCCAACTGGTCGGTGATAAAAAAGCGGTACGCCAAATGTT
GCTGTCCCAGTTGGGACGTAGCTTCCGGCAAGGAAAACATATTCTGCGGGTGCTCTATTACCGCCCATTGGAGAACTTAT
TACCCGGCACCGCCCTACGCCGCTCTGAAACCCATATGGTGCGGCAAATTTTTAACGGGCTGACACGGATAAATGAGGAA
AATGGGGAACTCGAACCGGACTTATCTCATCACTGGCAAGCGATCACCCCCTTGCATTGGCGCTTTTATTTGCGACCAGC
CATTCATTTCCACCATGGCCGGGAACTGGAAATGAGTGATGTGATTAGCAGCCTGACCCGCCTGATCCCCCAACCCCTGT
TTTCTCATATTGCGGAGGTGCGTTCACCGACACCTTATGTGATTGATGTTTATCTCCATTCGCCAGATCACTGGTTGCCA
TGGCTACTGGGCAGCGTTCACGCCATGATTTTGCCGCAAGAGTGGGAAACTCAGCCCGATTTTCACCGACAGCCTATTGG
TACCGGCCCTTATTCCGTGATCCGCAATCATCACAGCCAGCTGAAAATTCAGGCATTCGATAACTATTTTGGTTTCCGGG
CACTGATTGATGAGGTCAATATCTGGGTACTCCCAGAACTCTCCGAAGAATTGGTGTATTCCGGGGTGCAATTGCAAGCC
GACGATACGGGTAAAAATGAGCTGGAGAGCCGTTTAGAGGAAGGTTGCTACTTCTTACTGTTCGACCAACGATCCCCTCA
GGCCTGCACCCCGGAGATCCGCCGTTGGTTATGTGAATTGATCACACCGATAGCGTTACTCAGCCACGCCGCTCCCTTCT
ATCAACGTTACTGGTCACCGGCCTATGGCATGTTGCCACGCTGGCACCATAACCGACTCACCACTCAAGAGCCAAAACCC
GAAGGGCTGAACGAGCTGACACTGACGTTTTACAGCGAACATACAGAGTTTGATGCCATCAGCCAGACACTGACCCAGTT
ATTGGCTGCTCAGGGCGTGACGTTAAAGATACAAGTCTTGGACTACACCCGCTGGTATCAGGGGGATGCACAAAGCGATA
TCTGGCTCGGCAGCGCTAACTTTTACTTGCCACTCGAATTCTCGCTATTTGCCACCCTCTATGAAATGCCGCTACTACAA
CATTGTCTGAGCGAAGAACTGCATCAAGATATTGAATCCTGGCGCAATAATACCTTACTCATGGCCGATTGGAGCCAACG
ACTGGTAAGCCAGCATCAATTCCATCCGCTATTTCATCATTGGTTAGAATTATACGGTCAACACAGTATGCGGGGAGTGC
GTATGAATACACTCGGCTGGTTTGATTTTAAATCCGCATGGTTTACCCCACCAGAGGCCTAG

Upstream 100 bases:

>100_bases
GCATAGACGTTGTCACGATAACCCGCTTTTCTTGGGGGTTAGTATCTGCGTAATATAGGGAAAGAAAAATTGATGAGATT
TCCCAAGGAGTTCCTCTTTT

Downstream 100 bases:

>100_bases
GGCGGCGTTGACTCACACGGCGCTCCCCCTGAATTTATTATACAAACGGGCTGCACTACCCCTTTCAATAATTCCATTTA
TGAGAACGAGTTAAATACTC

Product: transcriptional regulator SgrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQR
AEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEE
NGELEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLP
WLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQA
DDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKP
EGLNELTLTFYSEHTEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQ
HCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA

Sequences:

>Translated_553_residues
MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQR
AEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEE
NGELEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLP
WLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQA
DDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKP
EGLNELTLTFYSEHTEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQ
HCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA
>Mature_552_residues
STSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAGRGKRSQLIFLRSGLALQQQRA
EELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKHILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEEN
GELEPDLSHHWQAITPLHWRFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLPW
LLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVNIWVLPELSEELVYSGVQLQAD
DTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCELITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKPE
GLNELTLTFYSEHTEFDAISQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQH
CLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGWFDFKSAWFTPPEA

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=552, Percent_Identity=62.6811594202899, Blast_Score=727, Evalue=0.0,
Organism=Escherichia coli, GI1786650, Length=572, Percent_Identity=29.020979020979, Blast_Score=201, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 64864; Mature: 64732

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAG
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RGKRSQLIFLRSGLALQQQRAEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKH
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEENGELEPDLSHHWQAITPLHW
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHH
RFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLP
HEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH
WLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVN
HHHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHCCCHHEEEEEHHHHHHHHHHHHHCC
IWVLPELSEELVYSGVQLQADDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCEL
EEECCCHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
ITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKPEGLNELTLTFYSEHTEFDAI
HHHHHHHHHCCHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHH
SQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQ
HHHHHHHHHHCCCEEEEEEEECHHHCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHH
HCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGW
HHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCCCC
FDFKSAWFTPPEA
EECCCCCCCCCCC
>Mature Secondary Structure 
STSRLQQQFIRLWQRYNGQSTETTLQALAEVLNCSRRHVRSLLGKMQHAGWLDWQAEAG
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RGKRSQLIFLRSGLALQQQRAEELLEQDHIDQLVQLVGDKKAVRQMLLSQLGRSFRQGKH
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ILRVLYYRPLENLLPGTALRRSETHMVRQIFNGLTRINEENGELEPDLSHHWQAITPLHW
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHH
RFYLRPAIHFHHGRELEMSDVISSLTRLIPQPLFSHIAEVRSPTPYVIDVYLHSPDHWLP
HEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHH
WLLGSVHAMILPQEWETQPDFHRQPIGTGPYSVIRNHHSQLKIQAFDNYFGFRALIDEVN
HHHHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHCCCHHEEEEEHHHHHHHHHHHHHCC
IWVLPELSEELVYSGVQLQADDTGKNELESRLEEGCYFLLFDQRSPQACTPEIRRWLCEL
EEECCCHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH
ITPIALLSHAAPFYQRYWSPAYGMLPRWHHNRLTTQEPKPEGLNELTLTFYSEHTEFDAI
HHHHHHHHHCCHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHH
SQTLTQLLAAQGVTLKIQVLDYTRWYQGDAQSDIWLGSANFYLPLEFSLFATLYEMPLLQ
HHHHHHHHHHCCCEEEEEEEECHHHCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHH
HCLSEELHQDIESWRNNTLLMADWSQRLVSQHQFHPLFHHWLELYGQHSMRGVRMNTLGW
HHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCCCC
FDFKSAWFTPPEA
EECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA