Definition | Streptococcus pneumoniae ATCC 700669, complete genome. |
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Accession | NC_011900 |
Length | 2,221,315 |
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The map label for this gene is pgi [H]
Identifier: 221232784
GI number: 221232784
Start: 2035708
End: 2037057
Strand: Reverse
Name: pgi [H]
Synonym: SPN23F_20950
Alternate gene names: 221232784
Gene position: 2037057-2035708 (Counterclockwise)
Preceding gene: 221232785
Following gene: 221232783
Centisome position: 91.71
GC content: 41.56
Gene sequence:
>1350_bases ATGTCACATATTAAATTTGATTATTCAAAAGTTTTAGACAAATTTGTTGCACCACATGAAGTGGAATACATGCAATCACA AGTAACAGCAGCAGATGAATTGATCCGTAAAGGAACTGGTGCTGGTAGCGACTTCTTGGGATGGTTGGACCTTCCTGAAA AATACGACCGCGAAGAATTTGACCGCATCTTGAAAGCTGCTGAGCAAATCAAGTCAGACAGCGATGTTTTGGTTGTGATC GGTATTGGTGGATCTTACCTTGGTGCAAAAGCAGCAATCGACTTCTTGAATCACCATTTTGCTAACTTGCAAACAAAAGA AGAACGCAAAGCTCCACAAATCCTTTACGCAGGAAACTCAATCTCATCTACTTACCTTGCTGACTTGGTAGAGTATGTTG CAGACAAAGACTTCTCAGTAAACGTAATTTCTAAATCAGGTACAACAACTGAACCAGCGATTGCTTTCCGTGTCTTTAAA GAACTCTTGGTTAAGAAATACGGTCAAGAAGAAGCTAACAAACGTATCTATGCAACAACTGACCGCCAAAAGGGTGCTGT TAAGGTTGAAGCAGACGCTAACGGTTGGGGAACATTTGTTGTTCCAGATGATATCGGTGGACGCTTCTCAGTATTGACAG CCGTTGGTTTGCTTCCAATCGCAGCATCAGGAGCTGACATCAAAGCTCTTATGGAAGGTGCGAATGCAGCTCGCAAAGAC TACACTTCAGACAAAATCTCTGAAAACGAAGCTTACCAATACGCAGTCGTTCGTAACATCCTTTATCGTAAAGGCTATGC AACTGAGATCTTGGTAAACTATGAGCCATCACTTCAATACTTCTCAGAATGGTGGAAACAATTGGCTGGTGAATCAGAAG GAAAAGACCAAAAAGGTATCTACCCAACTTCAGCCAACTTCTCAACTGACTTGCACTCACTTGGTCAATTTATCCAAGAA GGAACTCGTATCATGTTTGAAACAGTTGTCCGTGTTGACAAACCTCGTAAAAACGTGCTTATTCCTACTTTGGAAGAAGA CCTTGACGGACTTGGTTACCTTCAAGGAAAAGACGTTGACTTTGTAAACAAAAAAGCAACTGACGGTGTTCTTCTTGCCC ACACAGATGGTGATGTACCAAACATGTATGTGACTCTTCCAGAGCAAGACGCTTTCACTCTTGGTTACACTATCTACTTC TTCGAATTGGCAATTGCCCTTTCAGGTTACTTGAATGCTATCAACCCATTTGACCAACCAGGTGTTGAAGCTTATAAACG TAACATGTTTGCCCTTCTTGGAAAACCAGGATTTGAAGAATTGAGCAAAGAACTTAACGCACGTCTATAA
Upstream 100 bases:
>100_bases CGTTTGAATTCTGATAAAAATTGGAGAAATTCGACAAAAAAACTTGAAAAAAACGAAGGTAAGCGTTATGATAGAAAAGA AGAAATATTGGAGGAAGAAC
Downstream 100 bases:
>100_bases TAGAAGAAAAGAGTGGTTTGCCCACTCTTTTTACTCTCTTTATCCATAGAAATTGGACTCAGCCAAGACTTGTGATATAA TATAGAAAGCAAAAAGGCAG
Product: glucose-6-phosphate isomerase
Products: NA
Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]
Number of amino acids: Translated: 449; Mature: 448
Protein sequence:
>449_residues MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSDFLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVI GIGGSYLGAKAAIDFLNHHFANLQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLLPIAASGADIKALMEGANAARKD YTSDKISENEAYQYAVVRNILYRKGYATEILVNYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQE GTRIMFETVVRVDKPRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAFTLGYTIYF FELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL
Sequences:
>Translated_449_residues MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSDFLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVI GIGGSYLGAKAAIDFLNHHFANLQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLLPIAASGADIKALMEGANAARKD YTSDKISENEAYQYAVVRNILYRKGYATEILVNYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQE GTRIMFETVVRVDKPRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAFTLGYTIYF FELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL >Mature_448_residues SHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSDFLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIG IGGSYLGAKAAIDFLNHHFANLQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFKE LLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLLPIAASGADIKALMEGANAARKDY TSDKISENEAYQYAVVRNILYRKGYATEILVNYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEG TRIMFETVVRVDKPRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAFTLGYTIYFF ELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL
Specific function: Involved in glycolysis and in gluconeogenesis. [C]
COG id: COG0166
COG function: function code G; Glucose-6-phosphate isomerase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the GPI family [H]
Homologues:
Organism=Saccharomyces cerevisiae, GI6319673, Length=430, Percent_Identity=24.8837209302326, Blast_Score=74, Evalue=4e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001672 - InterPro: IPR018189 [H]
Pfam domain/function: PF00342 PGI [H]
EC number: =5.3.1.9 [H]
Molecular weight: Translated: 49907; Mature: 49776
Theoretical pI: Translated: 4.75; Mature: 4.75
Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.3 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSDFLGWLDLPEKYDREEF CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCHHHH DRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFANLQTKEERKAPQILYAGNS HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEECCC ISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATT CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEEEEC DRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLLPIAASGADIKALMEGANAARKD CCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHC YTSDKISENEAYQYAVVRNILYRKGYATEILVNYEPSLQYFSEWWKQLAGESEGKDQKGI CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC YPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDKPRKNVLIPTLEEDLDGLGYLQGKDVD CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHCCCCCCCCCCCCCC FVNKKATDGVLLAHTDGDVPNMYVTLPEQDAFTLGYTIYFFELAIALSGYLNAINPFDQP CCCCCCCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC GVEAYKRNMFALLGKPGFEELSKELNARL CHHHHHHHHHHHHCCCCHHHHHHHHCCCC >Mature Secondary Structure SHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSDFLGWLDLPEKYDREEF CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCHHHH DRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFANLQTKEERKAPQILYAGNS HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEECCC ISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATT CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHCCEEEEEC DRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLLPIAASGADIKALMEGANAARKD CCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHC YTSDKISENEAYQYAVVRNILYRKGYATEILVNYEPSLQYFSEWWKQLAGESEGKDQKGI CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC YPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDKPRKNVLIPTLEEDLDGLGYLQGKDVD CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHCCCCCCCCCCCCCC FVNKKATDGVLLAHTDGDVPNMYVTLPEQDAFTLGYTIYFFELAIALSGYLNAINPFDQP CCCCCCCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC GVEAYKRNMFALLGKPGFEELSKELNARL CHHHHHHHHHHHHCCCCHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA