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The map label for this gene is treR [H]

Identifier: 221232739

GI number: 221232739

Start: 1983185

End: 1983913

Strand: Reverse

Name: treR [H]

Synonym: SPN23F_20410

Alternate gene names: 221232739

Gene position: 1983913-1983185 (Counterclockwise)

Preceding gene: 221232744

Following gene: 221232738

Centisome position: 89.31

GC content: 35.12

Gene sequence:

>729_bases
ATGAGTACAAAATATTTATTTATTTACAATGAGATTCGTGAAAAGATTCTTTGTAATAAATATACCATGAACGAACAATT
GCCTGATGAAATGACATTAGCTAAACAGTTTGCCTGTAGTCGAATGACGATCAAAAAAGCTTTAGACTTGTTAGTTTCTG
AGGGCTTAATTTTTAGAAAACGTGGGCAGGGAACCTTTGTTCTCTCTCGTGGCAGCTCAAAAAGAAAATTAATCGTTCCA
GAAAGAGATATCCGGGGATTGACAAAAATATCTGAAGATGCTCATTCTACAATTGACTCGAGGATTATTCACTTCAAATT
AGAATTTGCAAATGAATTTTTAGCAGAAAAACTACAGGTCGCTTTGCAGAGTCCAGTTTATAATATTTACCGCCTGCGTA
TTATTGACGGTAAACCTTATGTTCTGGAACAAACTTATATGAGTACCGATGTTATTCCAGGTATTACTGAAGATATTTTA
CAAAAATCGATTTACAATTACATTGAAGGAAAGTTAGGATTGCATATTGCCAGTGCTACAAAAATCTTGCGAGCTTCTTC
TAGTTCAGAAAATGAGCAACATTACTTGCAGCTCCTTCCAACGGAACCGGTATTTGAAGTAGAACAAGTGGCTTATTTGG
ATAACGGAACTCCGTTTGAGTACTCGATTAGTCGTCATCGCTATGATTTATTTGAATTTAATTCTTTTGCATTACGACAT
TCCTCCTAG

Upstream 100 bases:

>100_bases
CTAGACATTTTTAAAAATTGTTGATACATATCTTGTGTTTGCCTCATTTCTTGAACTTTGTTATACTACTATTAGAATAT
TATAGAGAGAACCAGATTAA

Downstream 100 bases:

>100_bases
GAGAAAATGTGAAAATGAAGCCAATCTTTTACAGACTCTAGTTTAAGAAAAATTTAAAACAGGGCAAGAAGGTCCCATCT
ATGCTTAAATGGTTTCTCTT

Product: GntR-family transcriptional regulator

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTIKKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVP
ERDIRGLTKISEDAHSTIDSRIIHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTPFEYSISRHRYDLFEFNSFALRH
SS

Sequences:

>Translated_242_residues
MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTIKKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVP
ERDIRGLTKISEDAHSTIDSRIIHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTPFEYSISRHRYDLFEFNSFALRH
SS
>Mature_241_residues
STKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTIKKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPE
RDIRGLTKISEDAHSTIDSRIIHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDILQ
KSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTPFEYSISRHRYDLFEFNSFALRHS
S

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790118, Length=219, Percent_Identity=27.3972602739726, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786950, Length=241, Percent_Identity=29.4605809128631, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082252, Length=221, Percent_Identity=24.4343891402715, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788418, Length=209, Percent_Identity=27.7511961722488, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790540, Length=236, Percent_Identity=25.4237288135593, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27993; Mature: 27861

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTIKKALDLLVSEGLIFRK
CCCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
RGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRIIHFKLEFANEFLAEKLQV
CCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHH
ALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDILQKSIYNYIEGKLGLHIASAT
HHHCCCEEEEEEEEECCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCCHHCEEEHHHH
KILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTPFEYSISRHRYDLFEFNSFALRH
HHHHCCCCCCCCCEEEEECCCCCCHHHHHHEEECCCCCEEEECCCCEEEHHCCCCEEEEC
SS
CC
>Mature Secondary Structure 
STKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTIKKALDLLVSEGLIFRK
CCEEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
RGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRIIHFKLEFANEFLAEKLQV
CCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHH
ALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDILQKSIYNYIEGKLGLHIASAT
HHHCCCEEEEEEEEECCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCCHHCEEEHHHH
KILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTPFEYSISRHRYDLFEFNSFALRH
HHHHCCCCCCCCCEEEEECCCCCCHHHHHHEEECCCCCEEEECCCCEEEHHCCCCEEEEC
SS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]