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The map label for this gene is nrdR

Identifier: 221232449

GI number: 221232449

Start: 1656601

End: 1657074

Strand: Reverse

Name: nrdR

Synonym: SPN23F_17140

Alternate gene names: 221232449

Gene position: 1657074-1656601 (Counterclockwise)

Preceding gene: 221232453

Following gene: 221232448

Centisome position: 74.6

GC content: 42.19

Gene sequence:

>474_bases
ATGCGTTGTCCAAAATGTGGGGCTACCAAGTCAAGTGTTATCGATAGTCGCCAAGCAGAAGAAGGGAACACCATTCGTAG
AAGACGTGAGTGCGACGAATGCCAACACCGTTTTACAACCTACGAACGAGTAGAAGAAAGAACCTTAGTGGTTGTTAAAA
AAGATGGTACACGGGAACAATTCTCCAGAGATAAAATCTTTAATGGGATTATCCGCTCAGCCCAGAAACGTCCTGTGTCA
AGTGATGAAATCAACATGGTAGTCAATCGTATCGAACAGAAACTCCGTGGTCGAAATGAAAATGAAATTCAAAGTGAGGA
CATTGGTTCACTCGTCATGGAGGAGTTGGCTGAATTGGACGAGATTACCTATGTACGTTTTGCTAGTGTCTATCGTAGTT
TTAAGGATGTCAGTGAGTTAGAGAGCTTGCTCCAACAAATCACCCAGTCCTCTAAAAAGAAAAAGGAAAGATAA

Upstream 100 bases:

>100_bases
AATACAACAAAACAAAAAACTTGTCAAGCAAAAAGAAGAATTGTTTTGGGAATCGCTTAAAAAATGGTATAATGAAAAGA
AAACGATAAGGAGGGAAAGG

Downstream 100 bases:

>100_bases
ATGAAGCCAATTGACCGTTTTTCTTATCTAAAGAATAATCGGGTGTCGCAAGATACCTCATCTCTGGTACAGTGCTACCT
CCCGATTATCGGTCAGGAGG

Product: NrdR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVS
SDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER

Sequences:

>Translated_157_residues
MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVS
SDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER
>Mature_157_residues
MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVS
SDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=49.2857142857143, Blast_Score=147, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_STRP2 (Q04J60)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816978.1
- STRING:   Q04J60
- EnsemblBacteria:   EBSTRT00000020320
- GeneID:   4442319
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1523
- eggNOG:   COG1327
- GeneTree:   EBGT00050000027861
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18380; Mature: 18380

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQ
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHH
FSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQ
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHH
FSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA