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The map label for this gene is dtd

Identifier: 221232383

GI number: 221232383

Start: 1580679

End: 1581122

Strand: Reverse

Name: dtd

Synonym: SPN23F_16450

Alternate gene names: 221232383

Gene position: 1581122-1580679 (Counterclockwise)

Preceding gene: 221232384

Following gene: 221232379

Centisome position: 71.18

GC content: 41.44

Gene sequence:

>444_bases
ATGAAAATCATTATCCAACGGGTTAAAAAAGCCCAAGTGAGTATAGAAGGCCAGATTCAGGGAAAAATCAATCAGGGACT
TTTATTGCTGGTTGGTGTTGGACCAGAGGACCAAGAGGAAGATTTGGACTATGCTGTGAGAAAACTGGTCAATATGCGGA
TTTTTTCAGACGCAGAAGGCAAGATGAACCTGTCTGTCAAAGATATTGAAGGAGAAATCCTCTCTATTTCTCAGTTTACC
CTCTTTGCGGATACTAAGAAAGGCAATCGTCCAGCCTTTACAGGGGCAGCTAAACCTGATATGGCATCAGACTTCTATGA
TGCTTTCAATCAAAAATTAGCGCAAGAAGTGCCCGTTCAGACAGGTATCTTTGGAGCAGATATGCAGGTTGAGCTGGTTA
ATAACGGACCTGTTACCATTATCCTAGATACTAAAAAGAGATAA

Upstream 100 bases:

>100_bases
CACTGACCACGGTTGTCGATAAAATTAAGAGTGTGCCAGAAGTTTACTCTGTCAAACGGACCAACGGCTAGTTGTCCTAG
CTCTTACTAGAAAGGCTATT

Downstream 100 bases:

>100_bases
GAAAGACCAAGCCCAGTCGGCTTGGTCTTTCTCATCTATCATAAAATACTCCAAAAAGAAATCGGTTCTTGATATGCTTG
GGGGAAGTCTCTTTTCAGGC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFT
LFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR

Sequences:

>Translated_147_residues
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFT
LFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR
>Mature_147_residues
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFT
LFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=40.5405405405405, Blast_Score=109, Evalue=8e-25,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=50.3496503496504, Blast_Score=146, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=41.7218543046358, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=41.2162162162162, Blast_Score=113, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=40.1360544217687, Blast_Score=112, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_STRP2 (Q04JC5)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816913.1
- ProteinModelPortal:   Q04JC5
- SMR:   Q04JC5
- STRING:   Q04JC5
- EnsemblBacteria:   EBSTRT00000019437
- GeneID:   4442713
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1457
- eggNOG:   COG1490
- GeneTree:   EBGT00050000028308
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16214; Mature: 16214

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDAEG
CHHHHHHHHHHHEEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCCC
KMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQ
EEEEEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TGIFGADMQVELVNNGPVTIILDTKKR
CCEECCCEEEEEECCCCEEEEEECCCC
>Mature Secondary Structure
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDAEG
CHHHHHHHHHHHEEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHEEECCCCC
KMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQ
EEEEEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TGIFGADMQVELVNNGPVTIILDTKKR
CCEECCCEEEEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA