Definition Mycobacterium leprae Br4923 chromosome, complete genome.
Accession NC_011896
Length 3,268,071

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The map label for this gene is ccsB [H]

Identifier: 221230773

GI number: 221230773

Start: 2880916

End: 2882544

Strand: Reverse

Name: ccsB [H]

Synonym: MLBr_02410

Alternate gene names: 221230773

Gene position: 2882544-2880916 (Counterclockwise)

Preceding gene: 221230774

Following gene: 221230772

Centisome position: 88.2

GC content: 61.33

Gene sequence:

>1629_bases
TTGATGCAGGTTCTCATGCGGCTTCTGGCCTGGGTGCGCAACACGTGGCGTGCGCTTACCTCGATGGGTACTGCGCTGGT
GCTGTTGTTTTTGCTTGCGCTTGGCGCTATACCCGGTGCGTTGCTGCCGCAGCGCGACCTCAACGTTGGCAAGGTCGACG
ACTACGTGGCTGCTCACCCGGTAATCGGGTCGTGGCTGGACCAGTTGCAGGCCTTCAACGTGTTTTCCAGCGTCTGGTTC
ACCGCCATCTACACGTTACTGTTCGTATCCCTCGTCGGCTGTCTGACCCCGCGGATGATCGAGCATGCCCGCAGTCTGCG
CGCCATGCCGGTGATTGCCCCACGCAACCTGGCCCGGCTGCCCAAGCACGCCAGCTTCCAGGTCATCGGTGATGACAAGA
CTCTAGCGGGCACCATCGCTGGCAGGCTGCGCGGCTGGCGCACGGTCATTCGCACTCAAGACGGTGTAGTCCCCGAAACC
GTGGTGTCCGCTGAAAAGGGTTACCTGCGTGAATTCGGCAACCTGGTCTTTCACTTTTCGCTGCTGGGCCTGCTGGTTGC
GGTGGCCGTCGACAAGCTGTTCGGTTACGAGGGCAATGTTGTTGTCATCGCTGACGGTGGACCTGGCTTTTGCTCAGCAT
CGCCGGCTGCATTCGATGCGTTCCGTGCCGGCAACACCGTCGACGGAACTTCGTTGCATCCGATTTGCATTCGGGTAAAC
GACTTTGCGGCACATTACTTGCCCTCGGGACAGGCTATGTCGTTTACTGCGGATATTGACTATCAGGATGGTCACGATTT
GACGGTGAATAGCTGGCGGCCCTACCGGTTGGAAGTCAACCACCCACTGCGCGTCGCCGGTAACCGGGTGTACTTGCAGG
GCCACGGCTACGCGCCCACCTTCACTGTGACATTCCCCGACGGACAGACGCGCACGTCGACCGTGCAATGGCGACCTGAA
AACCAGCAGACGCTACTGTCGTCGGGCGTGGTGCGCATCGACCCACCCGCAGGCAGCTATCCCAACATGAGCGAGCGTCG
TCAACACGAGATCGCGATCCAAGGCCTGTTGGCACCGACCGAGCAGCTAGACGGCACCTTGTTGTTGTCGCGTTTCCCAG
CGCTGAACGCCCCCGCGGTAGCCATCGACATTTACCGCGGCGATACCGGCCTGGACAGCGGGCGGCCTCAGTCGTTGTTC
ACTCTGGATCCCCGGCTGATCAATCAGGGCCGGCTGACCAAAGAGAAACGGGTCAATCTGCAGGCCGGCGAACAGGTCCG
GCTTGGCCAAGGTCCAGGGGCTGGCACCGTGGTGCGCTTCGATGGGGCTGTGCCGTTCGTCAATTTGCAGGTGTCACATG
ATCCCGGCCAGGCTTGGGTATTTGTTTTCGCCATAGCGATGATGGTCGGGCTAGTGGTGTCGCTGATGGTGCGTCGTCGC
CGGGTGTGGGTCAGGCTCACCCCGGCGGCCGGTACGGTGAACGTCGAACTAGGCGGCCTGGCCCGCACCGACAATTCCGG
ATGGGGCGATGAATTCGAGCGATTGACGGAGCGGCTATTGGCCGGGCTCGTCGCGGCTGACCGGACGCTTGCAGCGGCCA
GAAGGAGTTCTCAAATGGACGTCAAATGA

Upstream 100 bases:

>100_bases
TGCTCCTGATAGCGATCGGTGCGGCACTGATCGCCGGGGTGTGGGATGACTTTGTTTCGTGGCTGAGGGATGCCGTCGTC
AGTGACATGAGGGTGTCGAT

Downstream 100 bases:

>100_bases
ACACTCTGCACGTCAACATCGGCCTGGCGTGCTACTCCGACTGGGCGTTCACCTCGGCCGTGGTGGCGTTGGTGGTCGCT
CTGCTACTGTTGGCTTACGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MMQVLMRLLAWVRNTWRALTSMGTALVLLFLLALGAIPGALLPQRDLNVGKVDDYVAAHPVIGSWLDQLQAFNVFSSVWF
TAIYTLLFVSLVGCLTPRMIEHARSLRAMPVIAPRNLARLPKHASFQVIGDDKTLAGTIAGRLRGWRTVIRTQDGVVPET
VVSAEKGYLREFGNLVFHFSLLGLLVAVAVDKLFGYEGNVVVIADGGPGFCSASPAAFDAFRAGNTVDGTSLHPICIRVN
DFAAHYLPSGQAMSFTADIDYQDGHDLTVNSWRPYRLEVNHPLRVAGNRVYLQGHGYAPTFTVTFPDGQTRTSTVQWRPE
NQQTLLSSGVVRIDPPAGSYPNMSERRQHEIAIQGLLAPTEQLDGTLLLSRFPALNAPAVAIDIYRGDTGLDSGRPQSLF
TLDPRLINQGRLTKEKRVNLQAGEQVRLGQGPGAGTVVRFDGAVPFVNLQVSHDPGQAWVFVFAIAMMVGLVVSLMVRRR
RVWVRLTPAAGTVNVELGGLARTDNSGWGDEFERLTERLLAGLVAADRTLAAARRSSQMDVK

Sequences:

>Translated_542_residues
MMQVLMRLLAWVRNTWRALTSMGTALVLLFLLALGAIPGALLPQRDLNVGKVDDYVAAHPVIGSWLDQLQAFNVFSSVWF
TAIYTLLFVSLVGCLTPRMIEHARSLRAMPVIAPRNLARLPKHASFQVIGDDKTLAGTIAGRLRGWRTVIRTQDGVVPET
VVSAEKGYLREFGNLVFHFSLLGLLVAVAVDKLFGYEGNVVVIADGGPGFCSASPAAFDAFRAGNTVDGTSLHPICIRVN
DFAAHYLPSGQAMSFTADIDYQDGHDLTVNSWRPYRLEVNHPLRVAGNRVYLQGHGYAPTFTVTFPDGQTRTSTVQWRPE
NQQTLLSSGVVRIDPPAGSYPNMSERRQHEIAIQGLLAPTEQLDGTLLLSRFPALNAPAVAIDIYRGDTGLDSGRPQSLF
TLDPRLINQGRLTKEKRVNLQAGEQVRLGQGPGAGTVVRFDGAVPFVNLQVSHDPGQAWVFVFAIAMMVGLVVSLMVRRR
RVWVRLTPAAGTVNVELGGLARTDNSGWGDEFERLTERLLAGLVAADRTLAAARRSSQMDVK
>Mature_542_residues
MMQVLMRLLAWVRNTWRALTSMGTALVLLFLLALGAIPGALLPQRDLNVGKVDDYVAAHPVIGSWLDQLQAFNVFSSVWF
TAIYTLLFVSLVGCLTPRMIEHARSLRAMPVIAPRNLARLPKHASFQVIGDDKTLAGTIAGRLRGWRTVIRTQDGVVPET
VVSAEKGYLREFGNLVFHFSLLGLLVAVAVDKLFGYEGNVVVIADGGPGFCSASPAAFDAFRAGNTVDGTSLHPICIRVN
DFAAHYLPSGQAMSFTADIDYQDGHDLTVNSWRPYRLEVNHPLRVAGNRVYLQGHGYAPTFTVTFPDGQTRTSTVQWRPE
NQQTLLSSGVVRIDPPAGSYPNMSERRQHEIAIQGLLAPTEQLDGTLLLSRFPALNAPAVAIDIYRGDTGLDSGRPQSLF
TLDPRLINQGRLTKEKRVNLQAGEQVRLGQGPGAGTVVRFDGAVPFVNLQVSHDPGQAWVFVFAIAMMVGLVVSLMVRRR
RVWVRLTPAAGTVNVELGGLARTDNSGWGDEFERLTERLLAGLVAADRTLAAARRSSQMDVK

Specific function: Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment [H]

COG id: COG1333

COG function: function code O; ResB protein required for cytochrome c biosynthesis

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccs1/ccsB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007816 [H]

Pfam domain/function: PF05140 ResB [H]

EC number: NA

Molecular weight: Translated: 59214; Mature: 59214

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQVLMRLLAWVRNTWRALTSMGTALVLLFLLALGAIPGALLPQRDLNVGKVDDYVAAHP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCC
VIGSWLDQLQAFNVFSSVWFTAIYTLLFVSLVGCLTPRMIEHARSLRAMPVIAPRNLARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEECCCHHHHC
PKHASFQVIGDDKTLAGTIAGRLRGWRTVIRTQDGVVPETVVSAEKGYLREFGNLVFHFS
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
LLGLLVAVAVDKLFGYEGNVVVIADGGPGFCSASPAAFDAFRAGNTVDGTSLHPICIRVN
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEE
DFAAHYLPSGQAMSFTADIDYQDGHDLTVNSWRPYRLEVNHPLRVAGNRVYLQGHGYAPT
CHHHHHCCCCCEEEEEEECCCCCCCCEEECCCCCEEEEECCCEEECCCEEEEEECCCCCE
FTVTFPDGQTRTSTVQWRPENQQTLLSSGVVRIDPPAGSYPNMSERRQHEIAIQGLLAPT
EEEECCCCCCCCCEEEECCCCHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCH
EQLDGTLLLSRFPALNAPAVAIDIYRGDTGLDSGRPQSLFTLDPRLINQGRLTKEKRVNL
HHCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCEEEECHHHHCCCCCCHHHCCCC
QAGEQVRLGQGPGAGTVVRFDGAVPFVNLQVSHDPGQAWVFVFAIAMMVGLVVSLMVRRR
CCCCEEEECCCCCCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
RVWVRLTPAAGTVNVELGGLARTDNSGWGDEFERLTERLLAGLVAADRTLAAARRSSQMD
EEEEEEECCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VK
CC
>Mature Secondary Structure
MMQVLMRLLAWVRNTWRALTSMGTALVLLFLLALGAIPGALLPQRDLNVGKVDDYVAAHP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCC
VIGSWLDQLQAFNVFSSVWFTAIYTLLFVSLVGCLTPRMIEHARSLRAMPVIAPRNLARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEECCCHHHHC
PKHASFQVIGDDKTLAGTIAGRLRGWRTVIRTQDGVVPETVVSAEKGYLREFGNLVFHFS
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
LLGLLVAVAVDKLFGYEGNVVVIADGGPGFCSASPAAFDAFRAGNTVDGTSLHPICIRVN
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEE
DFAAHYLPSGQAMSFTADIDYQDGHDLTVNSWRPYRLEVNHPLRVAGNRVYLQGHGYAPT
CHHHHHCCCCCEEEEEEECCCCCCCCEEECCCCCEEEEECCCEEECCCEEEEEECCCCCE
FTVTFPDGQTRTSTVQWRPENQQTLLSSGVVRIDPPAGSYPNMSERRQHEIAIQGLLAPT
EEEECCCCCCCCCEEEECCCCHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCH
EQLDGTLLLSRFPALNAPAVAIDIYRGDTGLDSGRPQSLFTLDPRLINQGRLTKEKRVNL
HHCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCEEEECHHHHCCCCCCHHHCCCC
QAGEQVRLGQGPGAGTVVRFDGAVPFVNLQVSHDPGQAWVFVFAIAMMVGLVVSLMVRRR
CCCCEEEECCCCCCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCC
RVWVRLTPAAGTVNVELGGLARTDNSGWGDEFERLTERLLAGLVAADRTLAAARRSSQMD
EEEEEEECCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]