Definition Mycobacterium leprae Br4923 chromosome, complete genome.
Accession NC_011896
Length 3,268,071

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The map label for this gene is ccsA [H]

Identifier: 221230772

GI number: 221230772

Start: 2879936

End: 2880919

Strand: Reverse

Name: ccsA [H]

Synonym: MLBr_02409

Alternate gene names: 221230772

Gene position: 2880919-2879936 (Counterclockwise)

Preceding gene: 221230773

Following gene: 221230771

Centisome position: 88.15

GC content: 62.5

Gene sequence:

>984_bases
ATGAACACTCTGCACGTCAACATCGGCCTGGCGTGCTACTCCGACTGGGCGTTCACCTCGGCCGTGGTGGCGTTGGTGGT
CGCTCTGCTACTGTTGGCTTACGAGCTAGCGTACGTTGGCAGCCGCCGGTTAGACAACCGCACGCGGGTGGTGCCCGGGT
CGGTCGCCGCCGACAGCGGGACCCCCGGTATCGTGGTGGACTCTCTGCAACGGCCGTTCGGCGAACGTGTCGGGCAGGCT
GGGTTGGCCGTGGCCTACCTTGGCATCGGTCTCTTGCTAGCGTGCATATTGCTGCGCGGCCTGGCCACCCTGCGTGTGCC
TTGGGGCAATATGTATGAGTTCATTAACCTGACCTGCTTCTCCGAGCTGGTCGCCGGCGCGATCGTGTTGCGTCGGCGAC
AGTACCGCCCGCTGTGGGTTTTCTTGCTGGTGTCGGTGTTGATCCTGCTCACGATTTCCGGTCGGTGGCTCTACGCCAAC
GCCGCACCGGTGATCCCGGCGCTGCAGTCCTACTGGCTGCCCATCCACGTGTCGGTGGTCAGCCTCGGCTCGGGGATTTT
CCTGGTCGCCGGCATCGCCAGCATCTTGTTCCTGCTGAGCACCTCGCGGCTGGTGGCCTCCGACCCCGAAGGTGCAAAGG
CACTGGCCCGGCTGGTGCGGCGGTTCCCTGACGCACAGACCCTGGACCGGATCGCCTATCGAACGACGATCTTTGCGTTT
CCGGTGTTTGGTTTCGGGGTGATCTTTGGTGCGATCTGGGCCGAGCAAGCCTGGGGCAGGTACTGGGGCTGGGATCCCAA
GGAGACGGTTTCTTTTGTTGCGTGGGTAGTATACGCAGCTTATCTACATGCCAGGTCGACCGCGGGATGGCGGGACAGGA
GGGCGGCGTGGATCAACGTGGTCGGGTGTGTTGCTATGGTCTTCAACCTGTTTTTCGTTAACCTGGTGACTGTAGGTCTG
CATTCGTATGCGGGAGTGGACTGA

Upstream 100 bases:

>100_bases
GCGATGAATTCGAGCGATTGACGGAGCGGCTATTGGCCGGGCTCGTCGCGGCTGACCGGACGCTTGCAGCGGCCAGAAGG
AGTTCTCAAATGGACGTCAA

Downstream 100 bases:

>100_bases
ATACTTGTTGGTGGACGGCTGAGTACTGCAGCCAATGGAGTAGTCGTCTCTCCGAGCATTCACGGTTGTAGACGCTCCGA
ACTTATGATGGCTATGGCGA

Product: putative cytochrome C biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGSRRLDNRTRVVPGSVAADSGTPGIVVDSLQRPFGERVGQA
GLAVAYLGIGLLLACILLRGLATLRVPWGNMYEFINLTCFSELVAGAIVLRRRQYRPLWVFLLVSVLILLTISGRWLYAN
AAPVIPALQSYWLPIHVSVVSLGSGIFLVAGIASILFLLSTSRLVASDPEGAKALARLVRRFPDAQTLDRIAYRTTIFAF
PVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARSTAGWRDRRAAWINVVGCVAMVFNLFFVNLVTVGL
HSYAGVD

Sequences:

>Translated_327_residues
MNTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGSRRLDNRTRVVPGSVAADSGTPGIVVDSLQRPFGERVGQA
GLAVAYLGIGLLLACILLRGLATLRVPWGNMYEFINLTCFSELVAGAIVLRRRQYRPLWVFLLVSVLILLTISGRWLYAN
AAPVIPALQSYWLPIHVSVVSLGSGIFLVAGIASILFLLSTSRLVASDPEGAKALARLVRRFPDAQTLDRIAYRTTIFAF
PVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARSTAGWRDRRAAWINVVGCVAMVFNLFFVNLVTVGL
HSYAGVD
>Mature_327_residues
MNTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGSRRLDNRTRVVPGSVAADSGTPGIVVDSLQRPFGERVGQA
GLAVAYLGIGLLLACILLRGLATLRVPWGNMYEFINLTCFSELVAGAIVLRRRQYRPLWVFLLVSVLILLTISGRWLYAN
AAPVIPALQSYWLPIHVSVVSLGSGIFLVAGIASILFLLSTSRLVASDPEGAKALARLVRRFPDAQTLDRIAYRTTIFAF
PVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARSTAGWRDRRAAWINVVGCVAMVFNLFFVNLVTVGL
HSYAGVD

Specific function: Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR017562 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 35844; Mature: 35844

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGSRRLDNRTRVVPGSVAADSG
CCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCC
TPGIVVDSLQRPFGERVGQAGLAVAYLGIGLLLACILLRGLATLRVPWGNMYEFINLTCF
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHH
SELVAGAIVLRRRQYRPLWVFLLVSVLILLTISGRWLYANAAPVIPALQSYWLPIHVSVV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCHHHEEEHH
SLGSGIFLVAGIASILFLLSTSRLVASDPEGAKALARLVRRFPDAQTLDRIAYRTTIFAF
HHCCCHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARSTAGWRDRRAAWINV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VGCVAMVFNLFFVNLVTVGLHSYAGVD
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGSRRLDNRTRVVPGSVAADSG
CCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCC
TPGIVVDSLQRPFGERVGQAGLAVAYLGIGLLLACILLRGLATLRVPWGNMYEFINLTCF
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHH
SELVAGAIVLRRRQYRPLWVFLLVSVLILLTISGRWLYANAAPVIPALQSYWLPIHVSVV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCHHHEEEHH
SLGSGIFLVAGIASILFLLSTSRLVASDPEGAKALARLVRRFPDAQTLDRIAYRTTIFAF
HHCCCHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARSTAGWRDRRAAWINV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VGCVAMVFNLFFVNLVTVGLHSYAGVD
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]