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The map label for this gene is argC

Identifier: 221230213

GI number: 221230213

Start: 1687605

End: 1688648

Strand: Direct

Name: argC

Synonym: MLBr_01406

Alternate gene names: 221230213

Gene position: 1687605-1688648 (Clockwise)

Preceding gene: 221230212

Following gene: 221230214

Centisome position: 51.64

GC content: 62.74

Gene sequence:

>1044_bases
ATGTCCTACGCGATAAGAGTGGCGGTTGTCGGTGCCAGCGGTTACGCGGGCGGCGAGATTCTTCGGTTGCTACTTGGGCA
TCCGGCGTACGCCGACGATCGGCTGACGATCGGCACGCTGACCGCCGCGGCCAGTTCGGGTGACACGCTCGGCGAGCACC
ATCCGCACTTGACGCCGCTGGCTCATCGAGTACTCGAATCTACTGAGTTGACCGTGCTAGCTGGCCACGACGTGGTTTTT
CTTGGCTTGCCACACGGACATTCGGCAGCGCTGGCCGAACGACTGGGTCCAGAAACACTGATCATCGACTGCGGTGCGGA
CTTCCGACTCACCGACGCCGGTGCCTGGGGGCGGTTCTACGAATCCCCGTATGCCGGCAGCTGGCCGTACGGGTTGCCAG
AGCTGCCCGGCGGTCGGGAGCGGTTACAAAAGGCACGCCGCATCGCGGTTCCCGGTTGCTACCCGACGGCCATCCTACTA
GCCTTGCTACCCGCGATGGCGGAGGGCCTTATCGAACCCGCCGTGACGGTGTTCGCGGTGAGCGGTATTTCCGGAGCCGG
TCGAGCAGCCAAGACCAAGTTGCTCGGCTCAGAGGTCATCGGTTCGGCAAGAGCCTATAACATTGGCGGTACCCACCGAC
ACACCGCCGAGATCATACAGGGGCTGCGGGTGGTGACCGATCGTGCTGTCACAGTGTCCTTCACCCCAGTGCTCATCCCT
ACTTCCCGCGGCATCCTAGCTGCCTGCACTGCGCGCACCTCCTCATCGCTCTCGAAGCTGCGCACCGCCTACGAAAAAGC
ATACCAAGTAGAGCCTTTCGTCTACCTGATGCCGGAGGGACAGTTGCCTTTCACCGGCGCAGTGATCGGCAGCAACGCGG
CGCATATCGCTGTTGCGGTGGACGAAGCTGCTGAGACGTTCATCGCGATCTCGGCGATCGACAATCTCGTCAAGGGCACC
GCTGGCGCCGCTGTGCAGTCGATGAACTTAGCGCTGGGTTGGCCGGAAGCAGAGGGCCTTTCAGTGGTTGGGGTGGCACC
GTGA

Upstream 100 bases:

>100_bases
TGTGATCCGATATCACGCCGAGTCACCAGTAAGTCAGAGCTATTTTCACTGAAGAAGAATGGATTTGCGAAATAATGCAT
AATTATTCATTATCTGCAAG

Downstream 100 bases:

>100_bases
CCAAAATAGTCGAAATAGTCAATGAGACGCGGCTGCTGCGCGCACAGGGCGTCACCGCCCCTGCGGGCTTTCAGGCCGCC
GGTATCACTGCTGGAATCAA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSYAIRVAVVGASGYAGGEILRLLLGHPAYADDRLTIGTLTAAASSGDTLGEHHPHLTPLAHRVLESTELTVLAGHDVVF
LGLPHGHSAALAERLGPETLIIDCGADFRLTDAGAWGRFYESPYAGSWPYGLPELPGGRERLQKARRIAVPGCYPTAILL
ALLPAMAEGLIEPAVTVFAVSGISGAGRAAKTKLLGSEVIGSARAYNIGGTHRHTAEIIQGLRVVTDRAVTVSFTPVLIP
TSRGILAACTARTSSSLSKLRTAYEKAYQVEPFVYLMPEGQLPFTGAVIGSNAAHIAVAVDEAAETFIAISAIDNLVKGT
AGAAVQSMNLALGWPEAEGLSVVGVAP

Sequences:

>Translated_347_residues
MSYAIRVAVVGASGYAGGEILRLLLGHPAYADDRLTIGTLTAAASSGDTLGEHHPHLTPLAHRVLESTELTVLAGHDVVF
LGLPHGHSAALAERLGPETLIIDCGADFRLTDAGAWGRFYESPYAGSWPYGLPELPGGRERLQKARRIAVPGCYPTAILL
ALLPAMAEGLIEPAVTVFAVSGISGAGRAAKTKLLGSEVIGSARAYNIGGTHRHTAEIIQGLRVVTDRAVTVSFTPVLIP
TSRGILAACTARTSSSLSKLRTAYEKAYQVEPFVYLMPEGQLPFTGAVIGSNAAHIAVAVDEAAETFIAISAIDNLVKGT
AGAAVQSMNLALGWPEAEGLSVVGVAP
>Mature_346_residues
SYAIRVAVVGASGYAGGEILRLLLGHPAYADDRLTIGTLTAAASSGDTLGEHHPHLTPLAHRVLESTELTVLAGHDVVFL
GLPHGHSAALAERLGPETLIIDCGADFRLTDAGAWGRFYESPYAGSWPYGLPELPGGRERLQKARRIAVPGCYPTAILLA
LLPAMAEGLIEPAVTVFAVSGISGAGRAAKTKLLGSEVIGSARAYNIGGTHRHTAEIIQGLRVVTDRAVTVSFTPVLIPT
SRGILAACTARTSSSLSKLRTAYEKAYQVEPFVYLMPEGQLPFTGAVIGSNAAHIAVAVDEAAETFIAISAIDNLVKGTA
GAAVQSMNLALGWPEAEGLSVVGVAP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=355, Percent_Identity=34.0845070422535, Blast_Score=132, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320913, Length=357, Percent_Identity=27.1708683473389, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_MYCLB (B8ZRK2)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503629.1
- ProteinModelPortal:   B8ZRK2
- SMR:   B8ZRK2
- EnsemblBacteria:   EBMYCT00000085570
- GeneID:   7326857
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000015828
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36032; Mature: 35900

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 153-153

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYAIRVAVVGASGYAGGEILRLLLGHPAYADDRLTIGTLTAAASSGDTLGEHHPHLTPL
CCEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHH
AHRVLESTELTVLAGHDVVFLGLPHGHSAALAERLGPETLIIDCGADFRLTDAGAWGRFY
HHHHHCCCCEEEEECCCEEEEECCCCCHHHHHHHCCCCEEEEECCCCEEEECCCCCHHHH
ESPYAGSWPYGLPELPGGRERLQKARRIAVPGCYPTAILLALLPAMAEGLIEPAVTVFAV
CCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
SGISGAGRAAKTKLLGSEVIGSARAYNIGGTHRHTAEIIQGLRVVTDRAVTVSFTPVLIP
ECCCCCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEEE
TSRGILAACTARTSSSLSKLRTAYEKAYQVEPFVYLMPEGQLPFTGAVIGSNAAHIAVAV
CCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCEEEEEEE
DEAAETFIAISAIDNLVKGTAGAAVQSMNLALGWPEAEGLSVVGVAP
CCHHHHHHHHHHHHHHHHCCCCHHHEECEEEEECCCCCCEEEEEECC
>Mature Secondary Structure 
SYAIRVAVVGASGYAGGEILRLLLGHPAYADDRLTIGTLTAAASSGDTLGEHHPHLTPL
CEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHH
AHRVLESTELTVLAGHDVVFLGLPHGHSAALAERLGPETLIIDCGADFRLTDAGAWGRFY
HHHHHCCCCEEEEECCCEEEEECCCCCHHHHHHHCCCCEEEEECCCCEEEECCCCCHHHH
ESPYAGSWPYGLPELPGGRERLQKARRIAVPGCYPTAILLALLPAMAEGLIEPAVTVFAV
CCCCCCCCCCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEE
SGISGAGRAAKTKLLGSEVIGSARAYNIGGTHRHTAEIIQGLRVVTDRAVTVSFTPVLIP
ECCCCCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEEEEEEE
TSRGILAACTARTSSSLSKLRTAYEKAYQVEPFVYLMPEGQLPFTGAVIGSNAAHIAVAV
CCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCEEEEEEE
DEAAETFIAISAIDNLVKGTAGAAVQSMNLALGWPEAEGLSVVGVAP
CCHHHHHHHHHHHHHHHHCCCCHHHEECEEEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA