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The map label for this gene is pafC

Identifier: 221230168

GI number: 221230168

Start: 1582181

End: 1583155

Strand: Direct

Name: pafC

Synonym: MLBr_01330

Alternate gene names: 221230168

Gene position: 1582181-1583155 (Clockwise)

Preceding gene: 221230167

Following gene: 221230169

Centisome position: 48.41

GC content: 61.74

Gene sequence:

>975_bases
ATGACACAGCTGTCCACCCGCCTAGTGCGGCTGCTCAATATGGTGCCGTACTTCCAGGCTAACCCGCGGATTACCCGTGC
GGAAGCTGCCGCCGATCTGGGAGTGTCTGCCAAGCAGCTAGACCAGGACTTCAACCAGCTGTGGGTGTGCGGTCTTCCTG
GCTATGGCCCTGGTGATCTCATTGACTTCGAGTTCTCTGGTGACACCATCGAGGTGACCTTCTCAGCGGGCATTGACCGG
CCTTTGCAGCTGACGTCGCCGGAGGCCATCGGCCTGTTGGTGGCGCTTCGGGCACTGGCCAACATTCCGGGAGTGGTTGA
TCCGGAGGCGGTGCGCAGCGCGATCGCCAAGATCGAGGCCGCAGCGGTTGTTATGGGGAACGAGGCCACTGGATCGGTGG
CCTCAGTCGATACGCGGCCGTTCTCCGAGAGTCACGCAGTGGCCGCAGTGCGTGCCGCGGTGCGGGACAAACAAGCATTG
GTGATCGACTACTACTCTGCGTCACATGACACTTTGACCAGCCGGATTGTCGACCCTATCCGAGTACTCCTGGTGGGTGA
TCACAGTTACCTTGAGGCTTGGTCGCGCGAAGCCGAAGGGGTTCGGCTGTTCCGCTTCGACCGGATCGTGGTGGCCCGCG
AGCTGGATGAGCCGGCCGCTGCACCTGAAACAGTGCGGAAGGCGCTGCCAGACACATCGTTCTTCGATGACGACCCGTTG
CTGCCGTCGGCGACGCTGTGGGTAGCGCGTTCGGTGTCCTGGATATTCGAGTACTACCCGATGCGGCAGGCCCATGAGTT
GCCGGATGGATCGTTCCAGGCGGTCATGACATACGCTTCGGATGCTTGGATGACGCGCTTGGTGCTAGGATTTGGGTCGG
CTGTGCAAGTACAAGCACCGGAGGCGCTCGCGTACCGCGTGCGGAATGCTGCGGTCGCTGCTCTGGAGTCCTACCAGGTT
ACGGCTCAGGCGTGA

Upstream 100 bases:

>100_bases
ACATCGCTGGCCACGGTGCTGACGCTGTCGTGCTCGAGCCAGACGCTCTGCGCGACGATGTGTTGATACGGTTGCGCGCC
CACGCGGGAACAGGGCCTTC

Downstream 100 bases:

>100_bases
TGCTGTGGTGCGGACGCCGATAGGTGGCGTTGCCGCGGTAGCATCCACTGGATGTCTGGAGGTAAATTTAAAGTGGGTAG
TCTTAGTCCATGGCACTGGG

Product: putative DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTQLSTRLVRLLNMVPYFQANPRITRAEAAADLGVSAKQLDQDFNQLWVCGLPGYGPGDLIDFEFSGDTIEVTFSAGIDR
PLQLTSPEAIGLLVALRALANIPGVVDPEAVRSAIAKIEAAAVVMGNEATGSVASVDTRPFSESHAVAAVRAAVRDKQAL
VIDYYSASHDTLTSRIVDPIRVLLVGDHSYLEAWSREAEGVRLFRFDRIVVARELDEPAAAPETVRKALPDTSFFDDDPL
LPSATLWVARSVSWIFEYYPMRQAHELPDGSFQAVMTYASDAWMTRLVLGFGSAVQVQAPEALAYRVRNAAVAALESYQV
TAQA

Sequences:

>Translated_324_residues
MTQLSTRLVRLLNMVPYFQANPRITRAEAAADLGVSAKQLDQDFNQLWVCGLPGYGPGDLIDFEFSGDTIEVTFSAGIDR
PLQLTSPEAIGLLVALRALANIPGVVDPEAVRSAIAKIEAAAVVMGNEATGSVASVDTRPFSESHAVAAVRAAVRDKQAL
VIDYYSASHDTLTSRIVDPIRVLLVGDHSYLEAWSREAEGVRLFRFDRIVVARELDEPAAAPETVRKALPDTSFFDDDPL
LPSATLWVARSVSWIFEYYPMRQAHELPDGSFQAVMTYASDAWMTRLVLGFGSAVQVQAPEALAYRVRNAAVAALESYQV
TAQA
>Mature_323_residues
TQLSTRLVRLLNMVPYFQANPRITRAEAAADLGVSAKQLDQDFNQLWVCGLPGYGPGDLIDFEFSGDTIEVTFSAGIDRP
LQLTSPEAIGLLVALRALANIPGVVDPEAVRSAIAKIEAAAVVMGNEATGSVASVDTRPFSESHAVAAVRAAVRDKQALV
IDYYSASHDTLTSRIVDPIRVLLVGDHSYLEAWSREAEGVRLFRFDRIVVARELDEPAAAPETVRKALPDTSFFDDDPLL
PSATLWVARSVSWIFEYYPMRQAHELPDGSFQAVMTYASDAWMTRLVLGFGSAVQVQAPEALAYRVRNAAVAALESYQVT
AQA

Specific function: Does not seem to be involved in pupylation or substrate degradation

COG id: COG2378

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pafC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAFC_MYCLE (P54075)

Other databases:

- EMBL:   U00017
- EMBL:   AL035310
- EMBL:   AL583921
- PIR:   D87075
- PIR:   S72859
- RefSeq:   NP_301954.1
- ProteinModelPortal:   P54075
- EnsemblBacteria:   EBMYCT00000029447
- GeneID:   908553
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1330
- NMPDR:   fig|272631.1.peg.826
- Leproma:   ML1330
- GeneTree:   EBGT00050000016807
- HOGENOM:   HBG428753
- OMA:   ASWMFEY
- ProtClustDB:   CLSK791625
- BioCyc:   MLEP272631:ML1330-MONOMER

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35259; Mature: 35128

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLSTRLVRLLNMVPYFQANPRITRAEAAADLGVSAKQLDQDFNQLWVCGLPGYGPGDL
CCCHHHHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCHHHHHHHHCEEEEECCCCCCCCCE
IDFEFSGDTIEVTFSAGIDRPLQLTSPEAIGLLVALRALANIPGVVDPEAVRSAIAKIEA
EEEEECCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AAVVMGNEATGSVASVDTRPFSESHAVAAVRAAVRDKQALVIDYYSASHDTLTSRIVDPI
EEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCE
RVLLVGDHSYLEAWSREAEGVRLFRFDRIVVARELDEPAAAPETVRKALPDTSFFDDDPL
EEEEECCHHHHHHHHCCCCCEEEEEEHHEEEEHHCCCCCCCHHHHHHHCCCCCCCCCCCC
LPSATLWVARSVSWIFEYYPMRQAHELPDGSFQAVMTYASDAWMTRLVLGFGSAVQVQAP
CCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECC
EALAYRVRNAAVAALESYQVTAQA
HHHHHHHHHHHHHHHHHCEEEECC
>Mature Secondary Structure 
TQLSTRLVRLLNMVPYFQANPRITRAEAAADLGVSAKQLDQDFNQLWVCGLPGYGPGDL
CCHHHHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCHHHHHHHHCEEEEECCCCCCCCCE
IDFEFSGDTIEVTFSAGIDRPLQLTSPEAIGLLVALRALANIPGVVDPEAVRSAIAKIEA
EEEEECCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AAVVMGNEATGSVASVDTRPFSESHAVAAVRAAVRDKQALVIDYYSASHDTLTSRIVDPI
EEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCE
RVLLVGDHSYLEAWSREAEGVRLFRFDRIVVARELDEPAAAPETVRKALPDTSFFDDDPL
EEEEECCHHHHHHHHCCCCCEEEEEEHHEEEEHHCCCCCCCHHHHHHHCCCCCCCCCCCC
LPSATLWVARSVSWIFEYYPMRQAHELPDGSFQAVMTYASDAWMTRLVLGFGSAVQVQAP
CCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECC
EALAYRVRNAAVAALESYQVTAQA
HHHHHHHHHHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002