| Definition | Mycobacterium leprae Br4923 chromosome, complete genome. |
|---|---|
| Accession | NC_011896 |
| Length | 3,268,071 |
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The map label for this gene is 221230112
Identifier: 221230112
GI number: 221230112
Start: 1482841
End: 1484316
Strand: Direct
Name: 221230112
Synonym: MLBr_01244
Alternate gene names: NA
Gene position: 1482841-1484316 (Clockwise)
Preceding gene: 221230111
Following gene: 221230113
Centisome position: 45.37
GC content: 60.37
Gene sequence:
>1476_bases ATGGCTGACTCCGTCGAGGGCATTGGACCGTTCGATGAACTGGGAGCGCTCGACTATCTGCTGCATCGGGGTGAGGCAAA TCCACGGACCCGCGCCGGGATCATGGCGGTGGAACTTTTGGATACCACACCGGACTGGAATCGGTTCCGGAGCCGGATCG AGGATGTCTCCCAACGAGTGTTGCGGCTGCGGCAGAAGGTTGTAGTACCGACATTGCCTACCGCCGCACCACGCTGGGTG GTGGATCCCGACTTCGAACTGGACTTTCATGTGCGTCGGGTGCGCGTGCCTGATCCGGGTACGTTGCGCGAGGTATTCGA TCTTGCCGAGGTGATTCAGCAGTCACCGATGGACGTGTCGCGGCCACTGTGGACGGCTACCTTGGTCGAGGGCCTGGCCG CTGGCAGGGCTGCGATGCTATTGCAGATTAGCCATGCGATCACCGACGGTGTCGGCAGTGTCGAGATGTTCGCCGAAATG TATGACTTAGAAAGAGATCCGCCGTCTAGACCTCGGTCCCCGCAACCTATTCCGCAGGATCTGTCGCGCAATGACTTAAT GCTACAAGGCATCAACCACTTGCCGGTCGCCCTGGCAGGCGGTGTCGTGGGTGGGCTATCTGGGGTGGCGTCGGTGGCTG GGCGGGCAATTCTACGACCTGCTTCGACTGTATCAGGAGTCGTCGGTTACGTCCGGTCGGGGATCAGAGTGTTGAGCCAG GCTGCCGAACCGTCCCCGTTGCTGCGCCAGCGCAGCCTGGCTACTCGCACCGAGGCAATAGAGATCCAGCTCTCCGACCT GCACAAGGCTGCGAAAGCGGGCGATGGGTCGATTAATGACGCTTATCTGGCCGGCTTGGTTGGTGCCTTGCGCCGCTACC ATGAGGCACTTGGTGTGTCGATCAGCACGCTGCCGATGGCGGTGCCGGTAAACGTACGGACTGAAGCCGATGTGGTTGGA AGCAACCGATTTGTTGGCGTTACCTTGGCGGCACCGCTCGGTACCAATGATCCGGCAGCCCGGATGCAGAAGATTCGTTC GCAGATGACGCAGCGGCGCGACGAGCCTGCAATGAACATCATTGGTTCCCTCGCACCGTTGATGACAGTACTACCGGCAT CGGTGCTAGATTTTATCGTTGACTCTGTGGCCAGCTCCGATGTGAATGCCAGTAATATTCCGGCCTACCCCGGGGACACC TACTTCGCGGGTGCAAAAATCTTGCGGCAGTATGGTATAGGACCTCGCCCTGGTGTAGCGATGATGGCGGTGCTGATGTC TCGAGGCGGGTTCTGCACGGTCACTGTGCGATACGATCGGGCTTCGGTGAAAAGCGAGGCATTGTTTGCCCGGTGCCTGC TGGAGGGTTTCGACGAGGTCCTGGCGTTGGCCGGTGACCCGACACCGCACGCTGTGCCGGCATCGTTTGCTGCGCGGTCC TCCGGTTCGCCGGCGGGATGGTTGTCGAGCTCATGA
Upstream 100 bases:
>100_bases GTGAACCCGACTAGCGTTGGGTAGGCAATTAGGTGGGGGGACTGAGTGCAGGAGGCGTGGTTGGCGGTGACAACGTACTG GTGGGCGTGGGGTCGTTCTG
Downstream 100 bases:
>100_bases GTGCCTTCGACGAGAACGGGACGCCCAAGTCAGGGCCGGAAGTGCGCTTGCCTGGTTCGGTCGCCGAGATCCTTGCCAGT CCTGCTGGTCCCCAGGTAGG
Product: hypothetical protein
Products: NA
Alternate protein names: Putative triacylglycerol synthase Rv2484c/MT2557 [H]
Number of amino acids: Translated: 491; Mature: 490
Protein sequence:
>491_residues MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWV VDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAITDGVGSVEMFAEM YDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQ AAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHEALGVSISTLPMAVPVNVRTEADVVG SNRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDT YFAGAKILRQYGIGPRPGVAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARS SGSPAGWLSSS
Sequences:
>Translated_491_residues MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWV VDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAITDGVGSVEMFAEM YDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQ AAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHEALGVSISTLPMAVPVNVRTEADVVG SNRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDT YFAGAKILRQYGIGPRPGVAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARS SGSPAGWLSSS >Mature_490_residues ADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVV DPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAITDGVGSVEMFAEMY DLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQA AEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHEALGVSISTLPMAVPVNVRTEADVVGS NRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDTY FAGAKILRQYGIGPRPGVAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARSS GSPAGWLSSS
Specific function: Upon expression in E.coli functions very weakly as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Has no wax synthase activity [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the long-chain O-acyltransferase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014292 - InterPro: IPR004255 [H]
Pfam domain/function: PF03007 UPF0089 [H]
EC number: =2.3.1.20 [H]
Molecular weight: Translated: 52450; Mature: 52319
Theoretical pI: Translated: 6.64; Mature: 6.64
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFRSRIEDVSQRV CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCEEEEEEECCCCCHHHHHHHHHHHHHHH LRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVS HHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHH RPLWTATLVEGLAAGRAAMLLQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQD CHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC LSRNDLMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQ CCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH AAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHEALGVS CCCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC ISTLPMAVPVNVRTEADVVGSNRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNI HHHCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHH IGSLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIGPRPGVA HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHH MMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARS HHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC SGSPAGWLSSS CCCCCCCCCCC >Mature Secondary Structure ADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFRSRIEDVSQRV CCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCEEEEEEECCCCCHHHHHHHHHHHHHHH LRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVS HHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCHH RPLWTATLVEGLAAGRAAMLLQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQD CHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC LSRNDLMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQ CCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH AAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHEALGVS CCCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC ISTLPMAVPVNVRTEADVVGSNRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNI HHHCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHH IGSLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDTYFAGAKILRQYGIGPRPGVA HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHH MMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARS HHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC SGSPAGWLSSS CCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]