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The map label for this gene is 221230099

Identifier: 221230099

GI number: 221230099

Start: 1443831

End: 1444427

Strand: Direct

Name: 221230099

Synonym: MLBr_01222

Alternate gene names: NA

Gene position: 1443831-1444427 (Clockwise)

Preceding gene: 221230098

Following gene: 221230101

Centisome position: 44.18

GC content: 63.48

Gene sequence:

>597_bases
GTGACCGAACATTGCGCGTCGGACATTTCCGATGTCTCCTGCCCACCGCGGGGGCGTGTGATCGTCGGGGTGGTGCTGGG
CCTTGCGGGGACTGGCGCGTTGATAGGCGGGCTGTGGGCCTGGATTGCCCCACCGATCCATGCGGTAGTGGGGCTCACGC
GGACAGGCGAACGAGGGCACGACTACCTGGGCAACGAGTCCGAGCACTTCTTTGTCGCGCCATGCTTGATGTTGGGCTTA
TTAACTGTGCTGGCGGTTACGGCGTCGGTGCTGGCATGGCAGTTGCGTCAGCACCGTGGGCCGGGGATGGTTATCGGGCT
CGCGATTGGCTTGATGATCTGCGCCGCAACTGCGGCAGCGGTGGGGGCGCTGTTGGTTTGGATGCGCTATGGTGCCTTGA
ATTTCGACGCAGTACCGCTGTCGTACGACCACAAAGTGGCGCACGTCATTCAAGCACCGCCGGTGTTCTTCGCGCACGGA
TTGCTGCAAGTAGCGGCCACCGTGCTATGGCCGGCGGGCATCGCTGCGCTGGTGTATGCGGTGCTTGCTGCCGCGAACGG
ACGCGACGACCTGGGCGGCAGACTATGTAGTCGGTAA

Upstream 100 bases:

>100_bases
AATGCGGACGGCGGATGGTTGTGCAGGTTCGTCCCGACGGCTGGCGGGCGAAGTGTTCGCGGCACGGACAGGTGGACTCG
GTCGACATGGAGGCAAAGCG

Downstream 100 bases:

>100_bases
GCCGCGAAGGCGCTACCATGGAGCCCGAAGCCTGTGTGCCGTAACAGCTGTCAGAGCGGGTGATGATGCACTTTCCCGCC
GATGATGACCTTGGGGCAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTEHCASDISDVSCPPRGRVIVGVVLGLAGTGALIGGLWAWIAPPIHAVVGLTRTGERGHDYLGNESEHFFVAPCLMLGL
LTVLAVTASVLAWQLRQHRGPGMVIGLAIGLMICAATAAAVGALLVWMRYGALNFDAVPLSYDHKVAHVIQAPPVFFAHG
LLQVAATVLWPAGIAALVYAVLAAANGRDDLGGRLCSR

Sequences:

>Translated_198_residues
MTEHCASDISDVSCPPRGRVIVGVVLGLAGTGALIGGLWAWIAPPIHAVVGLTRTGERGHDYLGNESEHFFVAPCLMLGL
LTVLAVTASVLAWQLRQHRGPGMVIGLAIGLMICAATAAAVGALLVWMRYGALNFDAVPLSYDHKVAHVIQAPPVFFAHG
LLQVAATVLWPAGIAALVYAVLAAANGRDDLGGRLCSR
>Mature_197_residues
TEHCASDISDVSCPPRGRVIVGVVLGLAGTGALIGGLWAWIAPPIHAVVGLTRTGERGHDYLGNESEHFFVAPCLMLGLL
TVLAVTASVLAWQLRQHRGPGMVIGLAIGLMICAATAAAVGALLVWMRYGALNFDAVPLSYDHKVAHVIQAPPVFFAHGL
LQVAATVLWPAGIAALVYAVLAAANGRDDLGGRLCSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv1591

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1222_MYCLE (Q49626)

Other databases:

- EMBL:   U00010
- EMBL:   AL583921
- PIR:   S72709
- RefSeq:   NP_301885.1
- EnsemblBacteria:   EBMYCT00000029063
- GeneID:   910550
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1222
- NMPDR:   fig|272631.1.peg.757
- Leproma:   ML1222
- GeneTree:   EBGT00050000017276
- HOGENOM:   HBG566955
- OMA:   GERVHDY
- ProtClustDB:   CLSK791270
- BioCyc:   MLEP272631:ML1222-MONOMER
- InterPro:   IPR021213

Pfam domain/function: PF10821 DUF2567

EC number: NA

Molecular weight: Translated: 20634; Mature: 20502

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x29f1b4e4)-; HASH(0x2997939c)-; HASH(0x29f0d510)-; HASH(0x29b6569c)-;

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHCASDISDVSCPPRGRVIVGVVLGLAGTGALIGGLWAWIAPPIHAVVGLTRTGERGH
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DYLGNESEHFFVAPCLMLGLLTVLAVTASVLAWQLRQHRGPGMVIGLAIGLMICAATAAA
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VGALLVWMRYGALNFDAVPLSYDHKVAHVIQAPPVFFAHGLLQVAATVLWPAGIAALVYA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAANGRDDLGGRLCSR
HHHHCCCCCCHHHHHCCH
>Mature Secondary Structure 
TEHCASDISDVSCPPRGRVIVGVVLGLAGTGALIGGLWAWIAPPIHAVVGLTRTGERGH
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DYLGNESEHFFVAPCLMLGLLTVLAVTASVLAWQLRQHRGPGMVIGLAIGLMICAATAAA
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VGALLVWMRYGALNFDAVPLSYDHKVAHVIQAPPVFFAHGLLQVAATVLWPAGIAALVYA
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAANGRDDLGGRLCSR
HHHHCCCCCCHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002