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The map label for this gene is acpS

Identifier: 221230083

GI number: 221230083

Start: 1405909

End: 1406301

Strand: Direct

Name: acpS

Synonym: MLBr_01192

Alternate gene names: 221230083

Gene position: 1405909-1406301 (Clockwise)

Preceding gene: 221230082

Following gene: 221230084

Centisome position: 43.02

GC content: 61.32

Gene sequence:

>393_bases
GTGGGCATTGTCGGCGTGGGAATCGACCTCGTCTCCATCCCTGATTTCGCCGAGCAGGTCAGCCAACCGGGAACGGTGTT
CATGACTATCTTCACTCCTGGTGAGCGTCGCGATGCCTCGGTCAAGAGTTCGTCGGCGGTGTGTCACCTGGCGGCGCGTT
GGGCTGTGAAGGAAGCGGTGATCAAGGCGTGGTCAGGATCGCGGTTCGCCCAGCGACCGATGCTGCCAGAGAACATCCAC
CGCGATATCGAGGTAGTCAACGACATGTGGGGCCGTCCGCGGGTCCGGCTCACCGGAGCCATCGCTAAGCATCTGACGGA
TGTGACGATCCATGTGTCGCTGACGCACGAAGGGGATATCGCGGCGGCAGTGGTGATCTTGGAGGTTCTGTGA

Upstream 100 bases:

>100_bases
AAGCTGCAAGAGGCAGCGATGTTGCTCAATCCGGCTGCTCGGCTTGGTGACGGCGATGCTTATATCGGATGAGTTCGGTC
ATCGGTTAACGTAGCACTTC

Downstream 100 bases:

>100_bases
GCTGGGGTACCTCCCCCGTTTGTGGGGAGGTACCCCAGCCGCCTGCGGCGCAAGCTGGCGTGCAGTAGACGCTGGACTAG
CCTCAAGCCATGAGTGATCT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MGIVGVGIDLVSIPDFAEQVSQPGTVFMTIFTPGERRDASVKSSSAVCHLAARWAVKEAVIKAWSGSRFAQRPMLPENIH
RDIEVVNDMWGRPRVRLTGAIAKHLTDVTIHVSLTHEGDIAAAVVILEVL

Sequences:

>Translated_130_residues
MGIVGVGIDLVSIPDFAEQVSQPGTVFMTIFTPGERRDASVKSSSAVCHLAARWAVKEAVIKAWSGSRFAQRPMLPENIH
RDIEVVNDMWGRPRVRLTGAIAKHLTDVTIHVSLTHEGDIAAAVVILEVL
>Mature_129_residues
GIVGVGIDLVSIPDFAEQVSQPGTVFMTIFTPGERRDASVKSSSAVCHLAARWAVKEAVIKAWSGSRFAQRPMLPENIHR
DIEVVNDMWGRPRVRLTGAIAKHLTDVTIHVSLTHEGDIAAAVVILEVL

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_MYCLB (B8ZR72)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503499.1
- ProteinModelPortal:   B8ZR72
- SMR:   B8ZR72
- EnsemblBacteria:   EBMYCT00000086669
- GeneID:   7325286
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016222
- HOGENOM:   HBG734479
- OMA:   RYSSAYS
- ProtClustDB:   PRK00070
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14138; Mature: 14006

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIVGVGIDLVSIPDFAEQVSQPGTVFMTIFTPGERRDASVKSSSAVCHLAARWAVKEAV
CCEEECCEEEEECCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
IKAWSGSRFAQRPMLPENIHRDIEVVNDMWGRPRVRLTGAIAKHLTDVTIHVSLTHEGDI
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCEEEEEEEEEECCCCH
AAAVVILEVL
HHHHHEEECC
>Mature Secondary Structure 
GIVGVGIDLVSIPDFAEQVSQPGTVFMTIFTPGERRDASVKSSSAVCHLAARWAVKEAV
CEEECCEEEEECCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
IKAWSGSRFAQRPMLPENIHRDIEVVNDMWGRPRVRLTGAIAKHLTDVTIHVSLTHEGDI
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCEEEEEEEEEECCCCH
AAAVVILEVL
HHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA