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The map label for this gene is yqjQ [H]

Identifier: 221229614

GI number: 221229614

Start: 528630

End: 529436

Strand: Reverse

Name: yqjQ [H]

Synonym: MLBr_00429

Alternate gene names: 221229614

Gene position: 529436-528630 (Counterclockwise)

Preceding gene: 221229616

Following gene: 221229613

Centisome position: 16.2

GC content: 60.22

Gene sequence:

>807_bases
ATGCCGATACCAGCACCCAGCCCCGAAGCGCGTGCCGTTGTGACCGGAGCTTCACAGAACATCGGCGAAGCGCTAGCCAC
CGAACTGGCCGCGCATGGACACAGCCTAATCGTGATCGCGCGGCGCGAAGACGTACTCGTCGACCTGGCAGCCCGTTTGG
CCGACAAATATCGTGTCGCAGTCGAAGTGCGACCGGCAGATCTCACCGACCCGTCTGAACGAGTGAAACTGGCCGATGAA
TTGACCGTGCGGCCCATTTCGATCCTGTGCGCCAACGCAGGTACAGCAACTTTCGGTCCGGTCTCTGCACTCGACCCGGC
AGGTGAAAAAGCTCAGGTCCAGCTGAATGCCGTAGCAGTGCACGACCTTACGTTAGCGGTACTGCCGGGCATGATCGAGC
GCAAGGCCGGTGGGATATTGATTTCCGGCTCGGCTGCCGGCAATTCACCGATCCCCTACAACGCCACTTATGCTGCTACC
AAGGCGTTCGCTAACACCTTCAGCGAATCGCTACGTGGGGAACTGCACGGCTCCGGCGTGCACGTCACGCTGCTGGCGCC
AGGCCCGGTACGCACTGAACTTCCCGATCACGACGAAGCATCGCTCGTGGAAAAATTGGTACCCGATTTCCTTTGGATCT
CGACAGAGCACACCGCGCGGCTTTCGCTGGATGCCTTGGAGCGCAACAAGATGCGCGTTGTCCCTGGGTTGACATCGAAA
GCCATGTCAGTGGCCAGTAGGTACGCCCCACGCGCCATCGTAGCGTCGATTGTGGGCAACTTCTACAAGAAGCTCGGCGG
CGGGTAG

Upstream 100 bases:

>100_bases
TGATTCATGCCCGGAACTTTACGGGGAGTGCACCCCACGGCGACCCCCGTTGCGCCCGACTCCGCCGCGCTTGCGATCGC
TGTATGTCTACCATTGGCGC

Downstream 100 bases:

>100_bases
ACGTTACTTGCGACGGCACTACCGGTAGTGTCGAACAGGGTGCGGATGAATTCGCGTATGGTCGGTCACGAAGGCACTCT
TCCCGGTCGGGTACTTCAGA

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLAARLADKYRVAVEVRPADLTDPSERVKLADE
LTVRPISILCANAGTATFGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAAT
KAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDHDEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSK
AMSVASRYAPRAIVASIVGNFYKKLGGG

Sequences:

>Translated_268_residues
MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLAARLADKYRVAVEVRPADLTDPSERVKLADE
LTVRPISILCANAGTATFGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAAT
KAFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDHDEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSK
AMSVASRYAPRAIVASIVGNFYKKLGGG
>Mature_267_residues
PIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLAARLADKYRVAVEVRPADLTDPSERVKLADEL
TVRPISILCANAGTATFGPVSALDPAGEKAQVQLNAVAVHDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATK
AFANTFSESLRGELHGSGVHVTLLAPGPVRTELPDHDEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSKA
MSVASRYAPRAIVASIVGNFYKKLGGG

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=187, Percent_Identity=34.7593582887701, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI226371731, Length=186, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=30.0518134715026, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI7706318, Length=204, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4557649, Length=204, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI223718074, Length=192, Percent_Identity=31.7708333333333, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7657478, Length=109, Percent_Identity=34.8623853211009, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=34.7826086956522, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786701, Length=204, Percent_Identity=30.3921568627451, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=34.7368421052632, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787335, Length=201, Percent_Identity=28.8557213930348, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212646214, Length=208, Percent_Identity=31.25, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25152911, Length=206, Percent_Identity=32.0388349514563, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560176, Length=261, Percent_Identity=27.9693486590038, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559552, Length=208, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557668, Length=208, Percent_Identity=28.3653846153846, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=209, Percent_Identity=29.1866028708134, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=35.2331606217617, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=195, Percent_Identity=28.7179487179487, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=35.0253807106599, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=33.8541666666667, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=33.8541666666667, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574402, Length=192, Percent_Identity=32.8125, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24584744, Length=192, Percent_Identity=32.8125, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24584752, Length=191, Percent_Identity=35.0785340314136, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24649181, Length=187, Percent_Identity=31.5508021390374, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24580925, Length=191, Percent_Identity=30.3664921465969, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=30.0518134715026, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24641388, Length=220, Percent_Identity=30, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28074; Mature: 27943

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLAARLADKYRVA
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCEEEE
VEVRPADLTDPSERVKLADELTVRPISILCANAGTATFGPVSALDPAGEKAQVQLNAVAV
EEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEE
HDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATKAFANTFSESLRGELHGSGV
HHHHHHHHCHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCE
HVTLLAPGPVRTELPDHDEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSK
EEEEECCCCCCCCCCCCCHHHHHHHHCCHHEEEECCCCCEEEHHHHCCCCEEECCCCHHH
AMSVASRYAPRAIVASIVGNFYKKLGGG
HHHHHHHHCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PIPAPSPEARAVVTGASQNIGEALATELAAHGHSLIVIARREDVLVDLAARLADKYRVA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCEEEE
VEVRPADLTDPSERVKLADELTVRPISILCANAGTATFGPVSALDPAGEKAQVQLNAVAV
EEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEE
HDLTLAVLPGMIERKAGGILISGSAAGNSPIPYNATYAATKAFANTFSESLRGELHGSGV
HHHHHHHHCHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCE
HVTLLAPGPVRTELPDHDEASLVEKLVPDFLWISTEHTARLSLDALERNKMRVVPGLTSK
EEEEECCCCCCCCCCCCCHHHHHHHHCCHHEEEECCCCCEEEHHHHCCCCEEECCCCHHH
AMSVASRYAPRAIVASIVGNFYKKLGGG
HHHHHHHHCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]