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The map label for this gene is cheB [H]

Identifier: 220933089

GI number: 220933089

Start: 2462036

End: 2463097

Strand: Reverse

Name: cheB [H]

Synonym: Hore_22570

Alternate gene names: 220933089

Gene position: 2463097-2462036 (Counterclockwise)

Preceding gene: 220933090

Following gene: 220933088

Centisome position: 95.54

GC content: 40.96

Gene sequence:

>1062_bases
ATGAGTAAAATCAGGGTTTTAGTAATTGATGATTCTCTTATGGTAAGAAAAATATTAACAAACACCCTGGAAAAGGATAA
TAACATTACTGTGGTTGGTACTGCCAGAGACCCCTATGAAGCTGTAAGTAAAATTACCTGTTTAAAACCTGATGTTCTAA
CGCTTGATGTAGAGATGCCCAGAATGAATGGACTTGAGTTCCTTAAAAAGCTTATGTCTTCCCATCCTATGCCAGTTATT
ATGGTGAGCACCCTTACTACCAGAGGAAGTGAAATTACTCTAAAGGCATTAAACGAAGGGGCAGTTGATTTTGTTGCCAA
GCCGTGTATATTTGGTAATAAGGAAAGGCAAATATTTCAACAGGAGATTATTAACAAAGTTAAGGTTGCTGCCAGGGTAG
ATGTGAGGAAATTGACCAGTTTTCGATACAGGACATCTACTGTTAGTAAGAAGGTTAACAAGCTAAGATACAGCAATTTA
CTTTCAAGGTATATCATAGGAATCGGGGCTTCTACTGGTGGGGTGAAGGCGATTAAGTATATTCTACCAGGGTTCCCCAG
GGAATCTCCTGGTATAGTAATTGTACAGCATATGCCAGGCGGGTTTACCAATTCTTTTGCCCGGCTGTTAAATAACATAA
GCACTCTTGATGTAAGGGAGGCTGCAACCGGTGATATTGTCAAACCGGGAACAGCCTTTGTGGCCCCGGGCGGTTATCAT
CTGGAGGTATTAAAAAAAGGGCATAACTTTTATATAAGGCTAAATAAAAATAAAAAAATTCACCACCAGCGCCCTGCTGT
AGATGTAACCTTCAAATCAATGGCAGAATGTGCCGGGAAAAACGCCATCGGTGTCCTGCTTACAGGTATGGGCCAGGATG
GTGCCAGGGGTTTAAAGAAAATCAGGCAAGCAGGTGGTTATACACTTGCCCAGGATAGGGAAACGGCGACCATTTTTGGT
ATGCCCAGAAAAGCTATTGAAATAGGTGCTGTTGACGAAGAGGTTTCAACCGGGGAAATAGTCGATAAGATATTTTTAAA
ATTAAATAATAACCACAGGTAG

Upstream 100 bases:

>100_bases
GATGTTGGGGGGAAACATGGCAGGCAGATATATTTCTGGCCCCGTAAAAATGTCTTTTCACGAAAAATCAAAATGACTGA
AATAAAGGATGTATCAGTTA

Downstream 100 bases:

>100_bases
TCATTAAATCTTTTATAATAAGGGGGTAACAATATGTTTAAATTTTTCAAAGAACGCCTTACAGTCAGGAATAAATTGTT
GACTTTTATACTGGTGCCTT

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSKIRVLVIDDSLMVRKILTNTLEKDNNITVVGTARDPYEAVSKITCLKPDVLTLDVEMPRMNGLEFLKKLMSSHPMPVI
MVSTLTTRGSEITLKALNEGAVDFVAKPCIFGNKERQIFQQEIINKVKVAARVDVRKLTSFRYRTSTVSKKVNKLRYSNL
LSRYIIGIGASTGGVKAIKYILPGFPRESPGIVIVQHMPGGFTNSFARLLNNISTLDVREAATGDIVKPGTAFVAPGGYH
LEVLKKGHNFYIRLNKNKKIHHQRPAVDVTFKSMAECAGKNAIGVLLTGMGQDGARGLKKIRQAGGYTLAQDRETATIFG
MPRKAIEIGAVDEEVSTGEIVDKIFLKLNNNHR

Sequences:

>Translated_353_residues
MSKIRVLVIDDSLMVRKILTNTLEKDNNITVVGTARDPYEAVSKITCLKPDVLTLDVEMPRMNGLEFLKKLMSSHPMPVI
MVSTLTTRGSEITLKALNEGAVDFVAKPCIFGNKERQIFQQEIINKVKVAARVDVRKLTSFRYRTSTVSKKVNKLRYSNL
LSRYIIGIGASTGGVKAIKYILPGFPRESPGIVIVQHMPGGFTNSFARLLNNISTLDVREAATGDIVKPGTAFVAPGGYH
LEVLKKGHNFYIRLNKNKKIHHQRPAVDVTFKSMAECAGKNAIGVLLTGMGQDGARGLKKIRQAGGYTLAQDRETATIFG
MPRKAIEIGAVDEEVSTGEIVDKIFLKLNNNHR
>Mature_352_residues
SKIRVLVIDDSLMVRKILTNTLEKDNNITVVGTARDPYEAVSKITCLKPDVLTLDVEMPRMNGLEFLKKLMSSHPMPVIM
VSTLTTRGSEITLKALNEGAVDFVAKPCIFGNKERQIFQQEIINKVKVAARVDVRKLTSFRYRTSTVSKKVNKLRYSNLL
SRYIIGIGASTGGVKAIKYILPGFPRESPGIVIVQHMPGGFTNSFARLLNNISTLDVREAATGDIVKPGTAFVAPGGYHL
EVLKKGHNFYIRLNKNKKIHHQRPAVDVTFKSMAECAGKNAIGVLLTGMGQDGARGLKKIRQAGGYTLAQDRETATIFGM
PRKAIEIGAVDEEVSTGEIVDKIFLKLNNNHR

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=349, Percent_Identity=45.5587392550143, Blast_Score=317, Evalue=9e-88,
Organism=Escherichia coli, GI87082052, Length=105, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38937; Mature: 38806

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIRVLVIDDSLMVRKILTNTLEKDNNITVVGTARDPYEAVSKITCLKPDVLTLDVEMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHEECCCCEEEEEECCC
RMNGLEFLKKLMSSHPMPVIMVSTLTTRGSEITLKALNEGAVDFVAKPCIFGNKERQIFQ
CCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHCCCCCCCHHHHHHH
QEIINKVKVAARVDVRKLTSFRYRTSTVSKKVNKLRYSNLLSRYIIGIGASTGGVKAIKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHH
ILPGFPRESPGIVIVQHMPGGFTNSFARLLNNISTLDVREAATGDIVKPGTAFVAPGGYH
HCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEHHCCCCCCCCCCCEEECCCCEE
LEVLKKGHNFYIRLNKNKKIHHQRPAVDVTFKSMAECAGKNAIGVLLTGMGQDGARGLKK
EEEEECCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEEEECCCCCHHHHHHH
IRQAGGYTLAQDRETATIFGMPRKAIEIGAVDEEVSTGEIVDKIFLKLNNNHR
HHHHCCCEEECCCCCEEEECCCHHHEEECCCCCCCCHHHHHHHHHHEECCCCC
>Mature Secondary Structure 
SKIRVLVIDDSLMVRKILTNTLEKDNNITVVGTARDPYEAVSKITCLKPDVLTLDVEMP
CCEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHEECCCCEEEEEECCC
RMNGLEFLKKLMSSHPMPVIMVSTLTTRGSEITLKALNEGAVDFVAKPCIFGNKERQIFQ
CCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHCCCCCCCHHHHHHH
QEIINKVKVAARVDVRKLTSFRYRTSTVSKKVNKLRYSNLLSRYIIGIGASTGGVKAIKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHH
ILPGFPRESPGIVIVQHMPGGFTNSFARLLNNISTLDVREAATGDIVKPGTAFVAPGGYH
HCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCEEHHCCCCCCCCCCCEEECCCCEE
LEVLKKGHNFYIRLNKNKKIHHQRPAVDVTFKSMAECAGKNAIGVLLTGMGQDGARGLKK
EEEEECCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEEEECCCCCHHHHHHH
IRQAGGYTLAQDRETATIFGMPRKAIEIGAVDEEVSTGEIVDKIFLKLNNNHR
HHHHCCCEEECCCCCEEEECCCHHHEEECCCCCCCCHHHHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]