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The map label for this gene is ziaR [H]

Identifier: 220933069

GI number: 220933069

Start: 2436433

End: 2436804

Strand: Reverse

Name: ziaR [H]

Synonym: Hore_22370

Alternate gene names: 220933069

Gene position: 2436804-2436433 (Counterclockwise)

Preceding gene: 220933070

Following gene: 220933068

Centisome position: 94.52

GC content: 38.44

Gene sequence:

>372_bases
TTGGACAAAAAAGAAGATTTCCCCTGTGATGTCTGTGAAGTCTTTGACCCCAATACCAAAATAGTTAAGATGCTGAAAGA
TACCCAGATAAATGATGAAATAATTAATAGATTAGCTGAATTATTTAAAACCATGTCTGATCCGACCAGGGTTAAAATTA
TTTATGCCTTGAGGGAGAGGGAGTTATGTGTCTGCGATATATCTGAGTTGTTAAATATGAGTCCTTCAGCTGTTTCCCAT
CAGCTAAGGGTATTGAGGAATATGAATCTTGTTAAGTATCGTAAAGAGGGTCGCTCTGTCTTTTATTCACTGGATGATGA
CCACGTTCTAACCCTGTTTAGCCAGGGTCTGGAACATGTCCTGGAAGAGTAA

Upstream 100 bases:

>100_bases
TGGGTGACCATCCAGATCAGCAAGATAAGGCTGGTATGACTTATTATATATAAGTTATGTTAAAATTACATTTATGGGTA
CAGGAGAGGAGGTCAGGGGT

Downstream 100 bases:

>100_bases
CCCATAATTTGTTACCTGTTTGTTAAAGGTATATAATATACTATAGGGATAGAATAAAGGATAAGATAAAGGAGGGGATT
AAAATTAAATCATACCGCGA

Product: regulatory protein ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MDKKEDFPCDVCEVFDPNTKIVKMLKDTQINDEIINRLAELFKTMSDPTRVKIIYALRERELCVCDISELLNMSPSAVSH
QLRVLRNMNLVKYRKEGRSVFYSLDDDHVLTLFSQGLEHVLEE

Sequences:

>Translated_123_residues
MDKKEDFPCDVCEVFDPNTKIVKMLKDTQINDEIINRLAELFKTMSDPTRVKIIYALRERELCVCDISELLNMSPSAVSH
QLRVLRNMNLVKYRKEGRSVFYSLDDDHVLTLFSQGLEHVLEE
>Mature_123_residues
MDKKEDFPCDVCEVFDPNTKIVKMLKDTQINDEIINRLAELFKTMSDPTRVKIIYALRERELCVCDISELLNMSPSAVSH
QLRVLRNMNLVKYRKEGRSVFYSLDDDHVLTLFSQGLEHVLEE

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14380; Mature: 14380

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKEDFPCDVCEVFDPNTKIVKMLKDTQINDEIINRLAELFKTMSDPTRVKIIYALRER
CCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
ELCVCDISELLNMSPSAVSHQLRVLRNMNLVKYRKEGRSVFYSLDDDHVLTLFSQGLEHV
CCCEECHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
LEE
HCC
>Mature Secondary Structure
MDKKEDFPCDVCEVFDPNTKIVKMLKDTQINDEIINRLAELFKTMSDPTRVKIIYALRER
CCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCC
ELCVCDISELLNMSPSAVSHQLRVLRNMNLVKYRKEGRSVFYSLDDDHVLTLFSQGLEHV
CCCEECHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
LEE
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]