BacMap

Definition	Halothermothrix orenii H 168 chromosome, complete genome.
Accession	NC_011899
Length	2,578,146

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The map label for this gene is yhdH [H]

Identifier: 220932923

GI number: 220932923

Start: 2265533

End: 2266846

Strand: Direct

Name: yhdH [H]

Synonym: Hore_20910

Alternate gene names: 220932923

Gene position: 2265533-2266846 (Clockwise)

Preceding gene: 220932922

Following gene: 220932924

Centisome position: 87.87

GC content: 43.68

Gene sequence:

>1314_bases
ATGAATCAAAGAGAAACATGGACCGGTAGAATTGGATTTATTCTGGCCTGTGTTGGTGCTGCGATAGGACTGGGTAATAT
ATGGATGTTTTCATGGAGGCTTGGGGCATATGGAGGTGCTGCCTTTTTAGTTCCCTATTTTATCTTTGTATTTGGACTGG
CCAGCACCGGATTAATGGAGGAATTCGCCTTCGGGAGAAGCCAGCAGAAAGGGGCCATAGGAGCCTTCGAAAATGTCTTT
AAAGATAAAAACCCTTCTCTGGGGGCAACCCTCGGAACCTTACCTGTTCTAGGTGTAAGTGGAGTTTTTATCTTCTATAT
TATCGTAGTTGGCTGGATATTAAAATATTTTGTCCTGGCTTTAACTAATTCCTTTGTCGGTATGGATATTGCAAACTACT
TTGGTCAGTTTGCCGGTAATAGTGCCAGTATCCTGTGGCATGCCCTGGCTGTAATTTTAACTCTGGCAATAGTTAAACTT
GGTGTTCAAAAGGGTATTGAAAAAACCAATAAATTTATGATGCCTACCCTGTTTATTCTATTAATCATCCTGATGATCAG
ATCCTTAACCCTGGGTGGTGCCATGGAAGGTGTTAAATTCATGCTGGTTCCAGACTGGTCAAAGCTATTACAGCCGGTTA
CCTGGGTAATGGCTCTGGGACAGGCCTTTTTTACCGTATCCCTGGGTGGAGCTGCTATGCTGGTTTACGGTAGTTATCTG
AGAAAAGATGAAGATATTCCATCTTCAGCCCTGCAGACAGTTGCTTTTAATACCAGTGCTTCCCTGCTGGCTGCCTTTGT
CATTATCCCGGCTGTCTTTGCCTTCGGTCTTGACCCTCAGGCAGGACCACCACTTCTTTTTATAACCCTGCCTAACATTT
TCAAGGCAATGCCGGGTGGATATATCTTTGGTGTCCTCTTCTTCTTAAGTATCGTATTTGCCGCTATATCATCTGCTGTA
AACCTTATGGAAGTACCTGTTGAAGCCATGATGGACAGATTAAATTTAAGCAGGGGAAAAAGCACCCTGATAGTCGCTTT
ACTTGGTTTTATTATAGGGTTACCCCTGGATACAAACATGGCCTGGTTTGGTAAATTTGCTGATTTTGTCACCATCTATC
TGGTGCCTATCGGGGCCGTTTTAGCAGCCTTCGTCTTTTTCTGGGTTTACGGTGTTTCTAAAGCCAGGCAGGAAATTAAC
CGGGGTTCTTCACGACCCCTGGGTAAATGGTGGGAACCTTTCGCTAAATATGTATTTGTGGCTGTAGCTCTAATTGTGCT
GATTCTCGGTGTTGTATATGGTGGTATTGGTTAA

Upstream 100 bases:

>100_bases
CAATATGGTTATGCCCCATTAATCTATCCCCACGGTTCGGTTTTATTTTTATTAATATTTTTTAAAATTATCAAAAAAAT
TAGAGTAGGGAGGAAAATTA

Downstream 100 bases:

>100_bases
AATTAAAAATGCTGGCCGTTCAATTAAAACGGCCGGCATTTATTATACAAAAACCTGAATTAATTCTGGTTTTTTCAATA
ACTGGCTTTGTTTTTTTTAA

Product: sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNQRETWTGRIGFILACVGAAIGLGNIWMFSWRLGAYGGAAFLVPYFIFVFGLASTGLMEEFAFGRSQQKGAIGAFENVF
KDKNPSLGATLGTLPVLGVSGVFIFYIIVVGWILKYFVLALTNSFVGMDIANYFGQFAGNSASILWHALAVILTLAIVKL
GVQKGIEKTNKFMMPTLFILLIILMIRSLTLGGAMEGVKFMLVPDWSKLLQPVTWVMALGQAFFTVSLGGAAMLVYGSYL
RKDEDIPSSALQTVAFNTSASLLAAFVIIPAVFAFGLDPQAGPPLLFITLPNIFKAMPGGYIFGVLFFLSIVFAAISSAV
NLMEVPVEAMMDRLNLSRGKSTLIVALLGFIIGLPLDTNMAWFGKFADFVTIYLVPIGAVLAAFVFFWVYGVSKARQEIN
RGSSRPLGKWWEPFAKYVFVAVALIVLILGVVYGGIG

Sequences:

>Translated_437_residues
MNQRETWTGRIGFILACVGAAIGLGNIWMFSWRLGAYGGAAFLVPYFIFVFGLASTGLMEEFAFGRSQQKGAIGAFENVF
KDKNPSLGATLGTLPVLGVSGVFIFYIIVVGWILKYFVLALTNSFVGMDIANYFGQFAGNSASILWHALAVILTLAIVKL
GVQKGIEKTNKFMMPTLFILLIILMIRSLTLGGAMEGVKFMLVPDWSKLLQPVTWVMALGQAFFTVSLGGAAMLVYGSYL
RKDEDIPSSALQTVAFNTSASLLAAFVIIPAVFAFGLDPQAGPPLLFITLPNIFKAMPGGYIFGVLFFLSIVFAAISSAV
NLMEVPVEAMMDRLNLSRGKSTLIVALLGFIIGLPLDTNMAWFGKFADFVTIYLVPIGAVLAAFVFFWVYGVSKARQEIN
RGSSRPLGKWWEPFAKYVFVAVALIVLILGVVYGGIG
>Mature_437_residues
MNQRETWTGRIGFILACVGAAIGLGNIWMFSWRLGAYGGAAFLVPYFIFVFGLASTGLMEEFAFGRSQQKGAIGAFENVF
KDKNPSLGATLGTLPVLGVSGVFIFYIIVVGWILKYFVLALTNSFVGMDIANYFGQFAGNSASILWHALAVILTLAIVKL
GVQKGIEKTNKFMMPTLFILLIILMIRSLTLGGAMEGVKFMLVPDWSKLLQPVTWVMALGQAFFTVSLGGAAMLVYGSYL
RKDEDIPSSALQTVAFNTSASLLAAFVIIPAVFAFGLDPQAGPPLLFITLPNIFKAMPGGYIFGVLFFLSIVFAAISSAV
NLMEVPVEAMMDRLNLSRGKSTLIVALLGFIIGLPLDTNMAWFGKFADFVTIYLVPIGAVLAAFVFFWVYGVSKARQEIN
RGSSRPLGKWWEPFAKYVFVAVALIVLILGVVYGGIG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=493, Percent_Identity=26.7748478701826, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI4507043, Length=386, Percent_Identity=27.720207253886, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7657587, Length=461, Percent_Identity=25.3796095444685, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI21361581, Length=457, Percent_Identity=24.507658643326, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4507041, Length=496, Percent_Identity=23.7903225806452, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI134304856, Length=460, Percent_Identity=23.9130434782609, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI171184408, Length=416, Percent_Identity=26.4423076923077, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI171184406, Length=416, Percent_Identity=26.4423076923077, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI171184404, Length=416, Percent_Identity=26.4423076923077, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI197276623, Length=349, Percent_Identity=26.647564469914, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI54607094, Length=349, Percent_Identity=26.647564469914, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI51468073, Length=297, Percent_Identity=26.2626262626263, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI194018524, Length=298, Percent_Identity=27.5167785234899, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI11181770, Length=294, Percent_Identity=27.5510204081633, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI33354281, Length=299, Percent_Identity=26.7558528428094, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI58219014, Length=299, Percent_Identity=26.7558528428094, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI67782317, Length=504, Percent_Identity=22.8174603174603, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI67782313, Length=504, Percent_Identity=22.8174603174603, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI67782315, Length=504, Percent_Identity=22.8174603174603, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI5032097, Length=466, Percent_Identity=25.7510729613734, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI289191351, Length=492, Percent_Identity=22.5609756097561, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4557046, Length=492, Percent_Identity=22.5609756097561, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI289191377, Length=492, Percent_Identity=22.5609756097561, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI218563756, Length=464, Percent_Identity=25.8620689655172, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI300360519, Length=420, Percent_Identity=23.0952380952381, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI92859670, Length=305, Percent_Identity=25.5737704918033, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI12408638, Length=275, Percent_Identity=24.3636363636364, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI197276625, Length=114, Percent_Identity=35.0877192982456, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI289191353, Length=307, Percent_Identity=23.1270358306189, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI21361693, Length=116, Percent_Identity=31.0344827586207, Blast_Score=66, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=440, Percent_Identity=26.3636363636364, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17555248, Length=483, Percent_Identity=24.4306418219462, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25146584, Length=499, Percent_Identity=24.6492985971944, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI133952791, Length=238, Percent_Identity=31.9327731092437, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71998244, Length=397, Percent_Identity=23.4256926952141, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI212642127, Length=426, Percent_Identity=22.0657276995305, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI115534083, Length=471, Percent_Identity=22.9299363057325, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17569475, Length=416, Percent_Identity=22.8365384615385, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24762620, Length=486, Percent_Identity=25.7201646090535, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI45551183, Length=436, Percent_Identity=25.4587155963303, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24654186, Length=526, Percent_Identity=23.9543726235741, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45550877, Length=431, Percent_Identity=25.2900232018561, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281365034, Length=476, Percent_Identity=23.109243697479, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17136952, Length=466, Percent_Identity=24.0343347639485, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281364394, Length=381, Percent_Identity=25.4593175853018, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574704, Length=381, Percent_Identity=25.4593175853018, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136950, Length=381, Percent_Identity=25.4593175853018, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574702, Length=381, Percent_Identity=25.4593175853018, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19921936, Length=460, Percent_Identity=24.7826086956522, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45551088, Length=454, Percent_Identity=23.7885462555066, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24652942, Length=454, Percent_Identity=23.7885462555066, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24661428, Length=456, Percent_Identity=24.5614035087719, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281364136, Length=478, Percent_Identity=25.3138075313808, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24639514, Length=416, Percent_Identity=25.2403846153846, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221329674, Length=398, Percent_Identity=25.3768844221106, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24639516, Length=302, Percent_Identity=27.4834437086093, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24582567, Length=453, Percent_Identity=25.1655629139073, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281363702, Length=478, Percent_Identity=23.0125523012552, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24655079, Length=295, Percent_Identity=25.7627118644068, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI19921352, Length=271, Percent_Identity=26.9372693726937, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24584353, Length=271, Percent_Identity=26.9372693726937, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24639853, Length=303, Percent_Identity=27.3927392739274, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281363700, Length=299, Percent_Identity=23.7458193979933, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582569, Length=276, Percent_Identity=27.536231884058, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 47341; Mature: 47341

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]