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The map label for this gene is yyaL [H]

Identifier: 220931972

GI number: 220931972

Start: 1226903

End: 1228978

Strand: Direct

Name: yyaL [H]

Synonym: Hore_11330

Alternate gene names: 220931972

Gene position: 1226903-1228978 (Clockwise)

Preceding gene: 220931970

Following gene: 220931974

Centisome position: 47.59

GC content: 35.5

Gene sequence:

>2076_bases
ATGATAGAATATACAAAAAGTAAATATACAAACAGGTTGATAAATGAAAAAAGCCCATATCTGCTTCAACATGCTCACAA
CCCGGTTGATTGGTATCCCTGGGGTAATGATGCCTTTATGAAGGCTAAAAGTGAAGATAAACCCATATTCCTTTCAATTG
GTTATTCAACGTGTCACTGGTGTCATGTCATGGAGAGGGAATCCTTTAAAGATGAAGAGGTAGCCAGGTTATTAAATGAG
AACTTCATATCGATTAAAGTTGATCGGGAAGAACGTCCTGATATTGATGCTGTATATATGAATGTATGTCAGGCATTGAC
AGGAAGTGGAGGCTGGCCTTTAACTATATTGTTAACCCCTGATAAAAAGCCTTTTTTTGGCGGGACCTATATTCCCAAAA
ACAGTAGAGGCGGAAGAATGGGTTTGATTGATCTTTTATCAAGAGTTACAGAATTATGGTCTAAGAATAATGAAAAAATT
ATAAAAAATGCAGATAAAATAACTTCAAGTATTCAAAGAAGTATGACCGATGATTCCTATAAGGGACATAAAGAAACATC
TCTTGGTAAAAATACCCTTGAGAAGGCATTTGATGATCTGAAAGTTGTTTTTGATGTTGAATACGGTGGATTTGGAACAG
CCCCCAAATTTCCAATTCCACATCAACTAATATTCTTACTCCATTACTGGTATAGAACAGGTAATGATATGGCTCTCTAT
ATGGTTGAAAAAACCCTTACAGCTATGAGGTGTGGTGGCATATTTGACCACATAGGGTATGGCTTTCATAGATATTCGAC
TGATCGCAAGTGGATACTTCCCCATTTTGAAAAAATGCTTTATGACCAGGCTTTACTTACATATAGTTATTCAGAGGCCT
ATTTAGCGACTGAAAATAAAAAGTTTTTAACAACTATCAAAGAAATAATTGACTATGTAAGAAGAGAGTTAAAGTCTGAC
AGGGGTGGTTTTTACTCTGCTCAGGATGCAGAAAGTGAAGGTGTTGAAGGGAAATACTATACATGGAGTGTTAAAGAAAT
AGAAAATATACTTGGCAAACAGGCTGACCGTTTTATAGAAACATATAGCCTGAAATCTGATGGTAATTTTATTGATGAAG
CAACCGGTAAAAAAACAGGGAAAAATGTACTTTATTTAAGGAATTATAAGGAAGAGGTAGAGGAGTTAAAAAAGGAAAGA
GAAAAATTGTTTAAGGTGCGGCAGAGAAGAAGACCACCTTTTAAAGATGATAAAATTTTAACTGACTGGAATGGTTTAAT
GATTGCTGGACTGGCCAGGGCAGGGCAGGCAACCGGGGAGATAGAATATATAACAATGGCCCGGGAGGCAGCTGACTTTA
TAATAAATAATTTATATTCCAGTGATAACCGCTTATACCACAGATTCCGTAAAGGTGAGGTCTCTATAAAAGGGAATTTA
AATGATTATGCCTTTTTTATCTGGGGTCTTCTGGAGCTTTACCAGGATACATTTGAGGTTAAATACTTAAAAAAAGCCTT
GAAATTAATAGACCAACAGCTTAATTACTTCTGGGATAATAAAAATGGTGGTTTTTATTTTACTCCTGATGATGAAGAGG
AGATTCTGGTAAGGCAGAAAGAAATATATGATGGGGCCACACCCTCCGGTAATTCAGTTTCTATATGGAATTTATATAGA
ATAGGCCATTTGACCGGAAACAGTGACTATGAAGAGATAGCAGAAAATATTTTAAGGGTTTTCTCTGATAAAATAAAAAA
TGATCCAGCTTCTTATAGCATGGCCCTGATTGGATTAAATTCATTGCTTGGTCCCGGGTATGATGTCGTTGTTGTTGGTG
ATAAAAATAAAGCAAAAACCCATAAAATACTTTATTCCCTCAAAAATGAATATATCCCAAATGTAAATACCCTGTTTAAA
CCTGCTCATAATGGGAAGATATTAACTGAACTGGGTCCCTTTATTGAAAATTACCATATGATTAATAATCTCCCCACCAT
TTATGTGTGTAAAGATTACTCCTGTCGCAGGCCAACCAATAATGTTGATGAGGCAATAAGTATGTTAAAAAAATAG

Upstream 100 bases:

>100_bases
AAGTTTAGGTTTTCTCAATACTGCCAGATAAAAATATAAAATTAACCATATTTATTATTACCTTATTATTAAAATAATAA
ATTTATAGGGGTGGTTTAAA

Downstream 100 bases:

>100_bases
ATGTAAAGCAGAAACAGGGCAAAATAGATCAATAGACAGGTAAATTAAAAACTAACCAGTATTCCCCCAAGGTCTGCATA
ACCTGAAATGGTTGGACCCA

Product: putative glutamate--cysteine ligase/putative amino acid ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MIEYTKSKYTNRLINEKSPYLLQHAHNPVDWYPWGNDAFMKAKSEDKPIFLSIGYSTCHWCHVMERESFKDEEVARLLNE
NFISIKVDREERPDIDAVYMNVCQALTGSGGWPLTILLTPDKKPFFGGTYIPKNSRGGRMGLIDLLSRVTELWSKNNEKI
IKNADKITSSIQRSMTDDSYKGHKETSLGKNTLEKAFDDLKVVFDVEYGGFGTAPKFPIPHQLIFLLHYWYRTGNDMALY
MVEKTLTAMRCGGIFDHIGYGFHRYSTDRKWILPHFEKMLYDQALLTYSYSEAYLATENKKFLTTIKEIIDYVRRELKSD
RGGFYSAQDAESEGVEGKYYTWSVKEIENILGKQADRFIETYSLKSDGNFIDEATGKKTGKNVLYLRNYKEEVEELKKER
EKLFKVRQRRRPPFKDDKILTDWNGLMIAGLARAGQATGEIEYITMAREAADFIINNLYSSDNRLYHRFRKGEVSIKGNL
NDYAFFIWGLLELYQDTFEVKYLKKALKLIDQQLNYFWDNKNGGFYFTPDDEEEILVRQKEIYDGATPSGNSVSIWNLYR
IGHLTGNSDYEEIAENILRVFSDKIKNDPASYSMALIGLNSLLGPGYDVVVVGDKNKAKTHKILYSLKNEYIPNVNTLFK
PAHNGKILTELGPFIENYHMINNLPTIYVCKDYSCRRPTNNVDEAISMLKK

Sequences:

>Translated_691_residues
MIEYTKSKYTNRLINEKSPYLLQHAHNPVDWYPWGNDAFMKAKSEDKPIFLSIGYSTCHWCHVMERESFKDEEVARLLNE
NFISIKVDREERPDIDAVYMNVCQALTGSGGWPLTILLTPDKKPFFGGTYIPKNSRGGRMGLIDLLSRVTELWSKNNEKI
IKNADKITSSIQRSMTDDSYKGHKETSLGKNTLEKAFDDLKVVFDVEYGGFGTAPKFPIPHQLIFLLHYWYRTGNDMALY
MVEKTLTAMRCGGIFDHIGYGFHRYSTDRKWILPHFEKMLYDQALLTYSYSEAYLATENKKFLTTIKEIIDYVRRELKSD
RGGFYSAQDAESEGVEGKYYTWSVKEIENILGKQADRFIETYSLKSDGNFIDEATGKKTGKNVLYLRNYKEEVEELKKER
EKLFKVRQRRRPPFKDDKILTDWNGLMIAGLARAGQATGEIEYITMAREAADFIINNLYSSDNRLYHRFRKGEVSIKGNL
NDYAFFIWGLLELYQDTFEVKYLKKALKLIDQQLNYFWDNKNGGFYFTPDDEEEILVRQKEIYDGATPSGNSVSIWNLYR
IGHLTGNSDYEEIAENILRVFSDKIKNDPASYSMALIGLNSLLGPGYDVVVVGDKNKAKTHKILYSLKNEYIPNVNTLFK
PAHNGKILTELGPFIENYHMINNLPTIYVCKDYSCRRPTNNVDEAISMLKK
>Mature_691_residues
MIEYTKSKYTNRLINEKSPYLLQHAHNPVDWYPWGNDAFMKAKSEDKPIFLSIGYSTCHWCHVMERESFKDEEVARLLNE
NFISIKVDREERPDIDAVYMNVCQALTGSGGWPLTILLTPDKKPFFGGTYIPKNSRGGRMGLIDLLSRVTELWSKNNEKI
IKNADKITSSIQRSMTDDSYKGHKETSLGKNTLEKAFDDLKVVFDVEYGGFGTAPKFPIPHQLIFLLHYWYRTGNDMALY
MVEKTLTAMRCGGIFDHIGYGFHRYSTDRKWILPHFEKMLYDQALLTYSYSEAYLATENKKFLTTIKEIIDYVRRELKSD
RGGFYSAQDAESEGVEGKYYTWSVKEIENILGKQADRFIETYSLKSDGNFIDEATGKKTGKNVLYLRNYKEEVEELKKER
EKLFKVRQRRRPPFKDDKILTDWNGLMIAGLARAGQATGEIEYITMAREAADFIINNLYSSDNRLYHRFRKGEVSIKGNL
NDYAFFIWGLLELYQDTFEVKYLKKALKLIDQQLNYFWDNKNGGFYFTPDDEEEILVRQKEIYDGATPSGNSVSIWNLYR
IGHLTGNSDYEEIAENILRVFSDKIKNDPASYSMALIGLNSLLGPGYDVVVVGDKNKAKTHKILYSLKNEYIPNVNTLFK
PAHNGKILTELGPFIENYHMINNLPTIYVCKDYSCRRPTNNVDEAISMLKK

Specific function: Unknown

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To C.elegans B0495.5 [H]

Homologues:

Organism=Homo sapiens, GI31542723, Length=730, Percent_Identity=38.7671232876712, Blast_Score=515, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI25147430, Length=734, Percent_Identity=36.2397820163488, Blast_Score=436, Evalue=1e-122,
Organism=Drosophila melanogaster, GI20129985, Length=733, Percent_Identity=36.8349249658936, Blast_Score=460, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819
- InterPro:   IPR004879
- InterPro:   IPR005198
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03190 DUF255; PF07221 GlcNAc_2-epim; PF03663 Glyco_hydro_76 [H]

EC number: NA

Molecular weight: Translated: 80026; Mature: 80026

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYTKSKYTNRLINEKSPYLLQHAHNPVDWYPWGNDAFMKAKSEDKPIFLSIGYSTCHW
CCCCCHHHHHHHHHCCCCCHHHHHCCCCCCEEECCCCCEEECCCCCCCEEEEECCCHHHH
CHVMERESFKDEEVARLLNENFISIKVDREERPDIDAVYMNVCQALTGSGGWPLTILLTP
HHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
DKKPFFGGTYIPKNSRGGRMGLIDLLSRVTELWSKNNEKIIKNADKITSSIQRSMTDDSY
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
KGHKETSLGKNTLEKAFDDLKVVFDVEYGGFGTAPKFPIPHQLIFLLHYWYRTGNDMALY
CCCCHHHCCHHHHHHHHCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
MVEKTLTAMRCGGIFDHIGYGFHRYSTDRKWILPHFEKMLYDQALLTYSYSEAYLATENK
EHHHHHHHHHHCCHHHHHCCCCEEECCCCCEECHHHHHHHHHHHHHHEECCCEEEEECCH
KFLTTIKEIIDYVRRELKSDRGGFYSAQDAESEGVEGKYYTWSVKEIENILGKQADRFIE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
TYSLKSDGNFIDEATGKKTGKNVLYLRNYKEEVEELKKEREKLFKVRQRRRPPFKDDKIL
HHEECCCCCCHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
TDWNGLMIAGLARAGQATGEIEYITMAREAADFIINNLYSSDNRLYHRFRKGEVSIKGNL
ECCCCCCEEHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCC
NDYAFFIWGLLELYQDTFEVKYLKKALKLIDQQLNYFWDNKNGGFYFTPDDEEEILVRQK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCHHHHHHHH
EIYDGATPSGNSVSIWNLYRIGHLTGNSDYEEIAENILRVFSDKIKNDPASYSMALIGLN
HHHCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHEEHEEEHH
SLLGPGYDVVVVGDKNKAKTHKILYSLKNEYIPNVNTLFKPAHNGKILTELGPFIENYHM
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEHHHHHHHHHHHHH
INNLPTIYVCKDYSCRRPTNNVDEAISMLKK
HCCCCEEEEECCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MIEYTKSKYTNRLINEKSPYLLQHAHNPVDWYPWGNDAFMKAKSEDKPIFLSIGYSTCHW
CCCCCHHHHHHHHHCCCCCHHHHHCCCCCCEEECCCCCEEECCCCCCCEEEEECCCHHHH
CHVMERESFKDEEVARLLNENFISIKVDREERPDIDAVYMNVCQALTGSGGWPLTILLTP
HHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECC
DKKPFFGGTYIPKNSRGGRMGLIDLLSRVTELWSKNNEKIIKNADKITSSIQRSMTDDSY
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
KGHKETSLGKNTLEKAFDDLKVVFDVEYGGFGTAPKFPIPHQLIFLLHYWYRTGNDMALY
CCCCHHHCCHHHHHHHHCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
MVEKTLTAMRCGGIFDHIGYGFHRYSTDRKWILPHFEKMLYDQALLTYSYSEAYLATENK
EHHHHHHHHHHCCHHHHHCCCCEEECCCCCEECHHHHHHHHHHHHHHEECCCEEEEECCH
KFLTTIKEIIDYVRRELKSDRGGFYSAQDAESEGVEGKYYTWSVKEIENILGKQADRFIE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
TYSLKSDGNFIDEATGKKTGKNVLYLRNYKEEVEELKKEREKLFKVRQRRRPPFKDDKIL
HHEECCCCCCHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
TDWNGLMIAGLARAGQATGEIEYITMAREAADFIINNLYSSDNRLYHRFRKGEVSIKGNL
ECCCCCCEEHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCC
NDYAFFIWGLLELYQDTFEVKYLKKALKLIDQQLNYFWDNKNGGFYFTPDDEEEILVRQK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCHHHHHHHH
EIYDGATPSGNSVSIWNLYRIGHLTGNSDYEEIAENILRVFSDKIKNDPASYSMALIGLN
HHHCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHEEHEEEHH
SLLGPGYDVVVVGDKNKAKTHKILYSLKNEYIPNVNTLFKPAHNGKILTELGPFIENYHM
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEHHHHHHHHHHHHH
INNLPTIYVCKDYSCRRPTNNVDEAISMLKK
HCCCCEEEEECCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]