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The map label for this gene is trpB [H]

Identifier: 220931970

GI number: 220931970

Start: 1224857

End: 1226053

Strand: Direct

Name: trpB [H]

Synonym: Hore_11310

Alternate gene names: 220931970

Gene position: 1224857-1226053 (Clockwise)

Preceding gene: 220931969

Following gene: 220931972

Centisome position: 47.51

GC content: 39.1

Gene sequence:

>1197_bases
ATGGCTTTAGATGTTAGACAACTGGAAGATGGTTTTTTTGGTAATTTTGGGGGGAGATATGTTCCGGAAAAATTAGTTCC
GGTTCTTGAAGAACTTAAAAAGGCATTTTTAAAATATAAGGATGATGAAAATTTTAATAAAGAGCTGGATTACTATTTAA
AAGAATATGTAGGGAGGGCTAACCCCCTGTATTTTGCTGAAAAATTATCAAAAAAATTAAATGGGGCCAGAATTTATTTA
AAGAGGGAAGATTTAAACCATACTGGTGCTCATAAAATTAATAATTGTATTGGTCAGGGGTTACTGGCCAAAAGAATGGG
TAAAAATAGGATTATTGCTGAAACTGGAGCAGGTCAACATGGGGTGGCAACTGCAACTGCCTGTGCTTTACTAGGTATGG
ACTGTGTTATTTATATGGGTGAAAAAGATACCAAACGGCAGGCCTTAAATGTATTCAGGATGGAGCTGTTGGGGGCTAAG
GTTGTCCCTGTTAAGACGGGAAGCCGTACTTTAAAAGATGCAGTTGATGAGGCCTTAAAAGATCTGATTGAAAACTATGA
TAATACTTTTTATATGCTCGGGTCAGCGGTAGGTCCTGATCCCTATCCTACAATAGTTAGACATTTTCAGTCTGTTATCG
GCAAGGAAGCTAAAAAACAGATAATTGAAAAAGAAGGTCGTCTGCCTGACTATATAATTGCCTGTGTCGGTGGTGGAAGT
AATGCTATTGGTCTGTTTTATCCCTTTATTGAAGATAAGGAGGTTAATATAATTGGAGTAGAACCGGGAGGAAAGGGCTC
AGAACCGGGGCAAAATGCAGCTCCCTTAAATTTTGGTGAGCCCGGTGTCTTACATGGTTTTATGTGCTATATGCTTAAAG
ATAAAAAAGGAAATGTTGCTTCTACCCATTCAATAGCAGCAGGACTTGATTATCCTGGTGTAGGACCGGAACATAGCTAT
TTAAAAGAAACAGGTCGGGCCCGGTATACAACCATAAATGATGAAGAAGCCCTTAAGGCTTTTAATCTTCTGTCACAGGT
TGAAGGTATTATTCCGGCCCTGGAAAGTTCCCACGCCGTTGCCCAGGCTATAAAGCTGGCTCCAGAATTAGATAAAAACC
AGATTATTATTGTTAATCTTTCAGGCCGGGGAGATAAAGATGTCCATCAGATTGCTGGTTTAATGGACAAAATTTAA

Upstream 100 bases:

>100_bases
CGAGGTTAGGTGAGGAGAGTATTTTGCTATATATTTTTTCAGGTACCTATAACCTTACTCACATGAGTAGGGTTTTTTTA
ATTTTAAGGAGGAGATATTA

Downstream 100 bases:

>100_bases
ATAGTTATATAGTTTATTAATAATTGTTTTACAGATTAAAAGTAATCTGTAGTATTTATTTACTTAAGCAAATTAAATAA
AGTATATTAAGGGAGCATGG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MALDVRQLEDGFFGNFGGRYVPEKLVPVLEELKKAFLKYKDDENFNKELDYYLKEYVGRANPLYFAEKLSKKLNGARIYL
KREDLNHTGAHKINNCIGQGLLAKRMGKNRIIAETGAGQHGVATATACALLGMDCVIYMGEKDTKRQALNVFRMELLGAK
VVPVKTGSRTLKDAVDEALKDLIENYDNTFYMLGSAVGPDPYPTIVRHFQSVIGKEAKKQIIEKEGRLPDYIIACVGGGS
NAIGLFYPFIEDKEVNIIGVEPGGKGSEPGQNAAPLNFGEPGVLHGFMCYMLKDKKGNVASTHSIAAGLDYPGVGPEHSY
LKETGRARYTTINDEEALKAFNLLSQVEGIIPALESSHAVAQAIKLAPELDKNQIIIVNLSGRGDKDVHQIAGLMDKI

Sequences:

>Translated_398_residues
MALDVRQLEDGFFGNFGGRYVPEKLVPVLEELKKAFLKYKDDENFNKELDYYLKEYVGRANPLYFAEKLSKKLNGARIYL
KREDLNHTGAHKINNCIGQGLLAKRMGKNRIIAETGAGQHGVATATACALLGMDCVIYMGEKDTKRQALNVFRMELLGAK
VVPVKTGSRTLKDAVDEALKDLIENYDNTFYMLGSAVGPDPYPTIVRHFQSVIGKEAKKQIIEKEGRLPDYIIACVGGGS
NAIGLFYPFIEDKEVNIIGVEPGGKGSEPGQNAAPLNFGEPGVLHGFMCYMLKDKKGNVASTHSIAAGLDYPGVGPEHSY
LKETGRARYTTINDEEALKAFNLLSQVEGIIPALESSHAVAQAIKLAPELDKNQIIIVNLSGRGDKDVHQIAGLMDKI
>Mature_397_residues
ALDVRQLEDGFFGNFGGRYVPEKLVPVLEELKKAFLKYKDDENFNKELDYYLKEYVGRANPLYFAEKLSKKLNGARIYLK
REDLNHTGAHKINNCIGQGLLAKRMGKNRIIAETGAGQHGVATATACALLGMDCVIYMGEKDTKRQALNVFRMELLGAKV
VPVKTGSRTLKDAVDEALKDLIENYDNTFYMLGSAVGPDPYPTIVRHFQSVIGKEAKKQIIEKEGRLPDYIIACVGGGSN
AIGLFYPFIEDKEVNIIGVEPGGKGSEPGQNAAPLNFGEPGVLHGFMCYMLKDKKGNVASTHSIAAGLDYPGVGPEHSYL
KETGRARYTTINDEEALKAFNLLSQVEGIIPALESSHAVAQAIKLAPELDKNQIIIVNLSGRGDKDVHQIAGLMDKI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=381, Percent_Identity=56.4304461942257, Blast_Score=443, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321412, Length=387, Percent_Identity=55.0387596899225, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43623; Mature: 43492

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDVRQLEDGFFGNFGGRYVPEKLVPVLEELKKAFLKYKDDENFNKELDYYLKEYVGRA
CCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
NPLYFAEKLSKKLNGARIYLKREDLNHTGAHKINNCIGQGLLAKRMGKNRIIAETGAGQH
CCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
GVATATACALLGMDCVIYMGEKDTKRQALNVFRMELLGAKVVPVKTGSRTLKDAVDEALK
CHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHH
DLIENYDNTFYMLGSAVGPDPYPTIVRHFQSVIGKEAKKQIIEKEGRLPDYIIACVGGGS
HHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
NAIGLFYPFIEDKEVNIIGVEPGGKGSEPGQNAAPLNFGEPGVLHGFMCYMLKDKKGNVA
CCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCC
STHSIAAGLDYPGVGPEHSYLKETGRARYTTINDEEALKAFNLLSQVEGIIPALESSHAV
CHHHHHCCCCCCCCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQAIKLAPELDKNQIIIVNLSGRGDKDVHQIAGLMDKI
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ALDVRQLEDGFFGNFGGRYVPEKLVPVLEELKKAFLKYKDDENFNKELDYYLKEYVGRA
CCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
NPLYFAEKLSKKLNGARIYLKREDLNHTGAHKINNCIGQGLLAKRMGKNRIIAETGAGQH
CCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
GVATATACALLGMDCVIYMGEKDTKRQALNVFRMELLGAKVVPVKTGSRTLKDAVDEALK
CHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHH
DLIENYDNTFYMLGSAVGPDPYPTIVRHFQSVIGKEAKKQIIEKEGRLPDYIIACVGGGS
HHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
NAIGLFYPFIEDKEVNIIGVEPGGKGSEPGQNAAPLNFGEPGVLHGFMCYMLKDKKGNVA
CCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCC
STHSIAAGLDYPGVGPEHSYLKETGRARYTTINDEEALKAFNLLSQVEGIIPALESSHAV
CHHHHHCCCCCCCCCCCHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHH
AQAIKLAPELDKNQIIIVNLSGRGDKDVHQIAGLMDKI
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA