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The map label for this gene is pgsA [H]

Identifier: 220931907

GI number: 220931907

Start: 1153470

End: 1153982

Strand: Direct

Name: pgsA [H]

Synonym: Hore_10650

Alternate gene names: 220931907

Gene position: 1153470-1153982 (Clockwise)

Preceding gene: 220931906

Following gene: 220931908

Centisome position: 44.74

GC content: 32.75

Gene sequence:

>513_bases
GTGAATATACTACCAAATTTACTAACCCTGGTCAGAATAGTATTAATTCCTGTATATATTAATTATTTTATAAGTGGTGA
TTATATCACTGCTGCAGTAATATTTTCTATATCAGGATTATCTGATTTTTTTGATGGTTTTCTGGCGAGAAGATACAATG
TAACAAGCAAGCTGGGGAGGATTTTGGACCCTCTGGCAGACAAACTTACTATTATAAGTATTTTGTTTTTACTGGTTACG
GTTGATATTATCCCTGAACTGGCTGCTATTGTTATTTTAACCAGAGAGATACTGGTATTATTGGGTTCAGGGATAGCATA
TGTTTTAGGAATAGATATGATTAATCCCAGTATCCTCGGGAAAATATCAGTTTTTTTATTATATGTCACCCTGGCCGGTA
AGCTTTTTGATATAAAATATATTGATATTATTCTTATATACATAGTTATTCCCTTAAATGTAATATCAGCAATAGGATAC
ACCATAACGGCGGTTAAAAAGGTCAGGGCCTAA

Upstream 100 bases:

>100_bases
GATAAATCATACAATATTATAACCAAGGATATAAAAGGAGGAACACTAATAACTGAAGAAGAATATAACAGCTAATTGAA
TTGAAACGGAGGAGTTTCCG

Downstream 100 bases:

>100_bases
AAATTAAAAATGTTTAAATCTGGATATTAATTTATATAGAGAATTATGGATAATTGTGGAATATAAATTATGCATTAAAG
ACGGTTTTGGAAAAAACCGT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MNILPNLLTLVRIVLIPVYINYFISGDYITAAVIFSISGLSDFFDGFLARRYNVTSKLGRILDPLADKLTIISILFLLVT
VDIIPELAAIVILTREILVLLGSGIAYVLGIDMINPSILGKISVFLLYVTLAGKLFDIKYIDIILIYIVIPLNVISAIGY
TITAVKKVRA

Sequences:

>Translated_170_residues
MNILPNLLTLVRIVLIPVYINYFISGDYITAAVIFSISGLSDFFDGFLARRYNVTSKLGRILDPLADKLTIISILFLLVT
VDIIPELAAIVILTREILVLLGSGIAYVLGIDMINPSILGKISVFLLYVTLAGKLFDIKYIDIILIYIVIPLNVISAIGY
TITAVKKVRA
>Mature_170_residues
MNILPNLLTLVRIVLIPVYINYFISGDYITAAVIFSISGLSDFFDGFLARRYNVTSKLGRILDPLADKLTIISILFLLVT
VDIIPELAAIVILTREILVLLGSGIAYVLGIDMINPSILGKISVFLLYVTLAGKLFDIKYIDIILIYIVIPLNVISAIGY
TITAVKKVRA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=120, Percent_Identity=38.3333333333333, Blast_Score=71, Evalue=4e-13,
Organism=Homo sapiens, GI10092647, Length=120, Percent_Identity=38.3333333333333, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1788220, Length=168, Percent_Identity=32.7380952380952, Blast_Score=83, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320059, Length=104, Percent_Identity=40.3846153846154, Blast_Score=64, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24650130, Length=103, Percent_Identity=38.8349514563107, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650126, Length=103, Percent_Identity=38.8349514563107, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650128, Length=103, Percent_Identity=38.8349514563107, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 18718; Mature: 18718

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILPNLLTLVRIVLIPVYINYFISGDYITAAVIFSISGLSDFFDGFLARRYNVTSKLGR
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDPLADKLTIISILFLLVTVDIIPELAAIVILTREILVLLGSGIAYVLGIDMINPSILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHH
KISVFLLYVTLAGKLFDIKYIDIILIYIVIPLNVISAIGYTITAVKKVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNILPNLLTLVRIVLIPVYINYFISGDYITAAVIFSISGLSDFFDGFLARRYNVTSKLGR
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDPLADKLTIISILFLLVTVDIIPELAAIVILTREILVLLGSGIAYVLGIDMINPSILG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHH
KISVFLLYVTLAGKLFDIKYIDIILIYIVIPLNVISAIGYTITAVKKVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA