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The map label for this gene is insF1 [C]

Identifier: 220931293

GI number: 220931293

Start: 483550

End: 484425

Strand: Reverse

Name: insF1 [C]

Synonym: Hore_04480

Alternate gene names: 220931293

Gene position: 484425-483550 (Counterclockwise)

Preceding gene: 220931294

Following gene: 220931288

Centisome position: 18.79

GC content: 34.13

Gene sequence:

>876_bases
ATGTATCCCGGTCAGGATATTACAGCTGGGTTAAAAAGAAAACCTGGCAAAAGAGAGTTAACAAATAAAAAGTTAAAGTT
GAAGATAGCTGAAATATACTGGCAGACCAGGGGAAGGTATGGTAGCCCCCGGATACATAAACAGCTTAAAAAAGAGGGTT
ATCATTATAATATTAAGCGTATTGAACGACTAATGAGGGTAATGGGATTAAAAGCAATACAGAAAAGAAAGTTTAAAAGG
ACAACTAATTCTGACAATAATCTCCCTTTAAAAAATAATCTTCTCAAACGTAATTTTAGCGTTACCCAACCTGATAAAGT
CTGGGTATCAGACATAACATATATTCCAACAAAAGAAGGCTGGCTTTATCTTTCAGTAGTGATTGACCTCTATTCTCGCA
GGGTTGTTGGTTGGTCAATGGACAATCATATGACAAAAAGGTTAGTGATTGATGCATTGGAAATGGCCGTACTAAATCGT
AATCCCTCCAGGGGATTAATTTTTCATTCTGACAGAGGTAGTCAGTATGCCAGCCATGATTTTCAAAAAACACTGTGGAA
ATACGGTATTATTTCATCAATGAGCCGCAAAGGTGATTGCTGGGACAATGCAGTAGCTGAAAGTTTTTTTGCAACACTAA
AAACAGAATTGATTTTCCACAACAAGTTTGTAAGTCTATTTAACTCTAACATTTTCTCAAAAGTAAATCATTACTATCTG
GCAAAATTCATATTTTTCCACTTCCACCTGCAATATTTATTGTCCACTACTGAGTGGAAATACCCGATAGTTACCTTTAT
AATTTCATATAAGTTGAATGGTAAACTTTCTCTTGCTGGTTTTTATTTTAAAAATAAAAATATACTAAAAATCTAA

Upstream 100 bases:

>100_bases
AAAAGCAGTGCGCATCTTCTTAAAGGAACCGAAATGATATATGGTTTCATCCGAGAACACAGTAATGAATTTGCTGTGGA
GAATATGTATCAGGTTTTAA

Downstream 100 bases:

>100_bases
TGCACGTCCATTAATTCTTAACCATTTCTGTTTCTCTCTATAATCCGTAATCACAGTTTCAACAAGCTCCCAGAAATTAA
CTGAATGATCGGGATGTATT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MYPGQDITAGLKRKPGKRELTNKKLKLKIAEIYWQTRGRYGSPRIHKQLKKEGYHYNIKRIERLMRVMGLKAIQKRKFKR
TTNSDNNLPLKNNLLKRNFSVTQPDKVWVSDITYIPTKEGWLYLSVVIDLYSRRVVGWSMDNHMTKRLVIDALEMAVLNR
NPSRGLIFHSDRGSQYASHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKFVSLFNSNIFSKVNHYYL
AKFIFFHFHLQYLLSTTEWKYPIVTFIISYKLNGKLSLAGFYFKNKNILKI

Sequences:

>Translated_291_residues
MYPGQDITAGLKRKPGKRELTNKKLKLKIAEIYWQTRGRYGSPRIHKQLKKEGYHYNIKRIERLMRVMGLKAIQKRKFKR
TTNSDNNLPLKNNLLKRNFSVTQPDKVWVSDITYIPTKEGWLYLSVVIDLYSRRVVGWSMDNHMTKRLVIDALEMAVLNR
NPSRGLIFHSDRGSQYASHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKFVSLFNSNIFSKVNHYYL
AKFIFFHFHLQYLLSTTEWKYPIVTFIISYKLNGKLSLAGFYFKNKNILKI
>Mature_291_residues
MYPGQDITAGLKRKPGKRELTNKKLKLKIAEIYWQTRGRYGSPRIHKQLKKEGYHYNIKRIERLMRVMGLKAIQKRKFKR
TTNSDNNLPLKNNLLKRNFSVTQPDKVWVSDITYIPTKEGWLYLSVVIDLYSRRVVGWSMDNHMTKRLVIDALEMAVLNR
NPSRGLIFHSDRGSQYASHDFQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKFVSLFNSNIFSKVNHYYL
AKFIFFHFHLQYLLSTTEWKYPIVTFIISYKLNGKLSLAGFYFKNKNILKI

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=203, Percent_Identity=37.4384236453202, Blast_Score=151, Evalue=5e-37,
Organism=Escherichia coli, GI1788405, Length=207, Percent_Identity=43.4782608695652, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1787263, Length=207, Percent_Identity=43.4782608695652, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1786753, Length=207, Percent_Identity=43.4782608695652, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1786570, Length=207, Percent_Identity=43.4782608695652, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1786490, Length=207, Percent_Identity=43.4782608695652, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789981, Length=204, Percent_Identity=39.2156862745098, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34385; Mature: 34385

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPGQDITAGLKRKPGKRELTNKKLKLKIAEIYWQTRGRYGSPRIHKQLKKEGYHYNIKR
CCCCCCCHHHHHCCCCCHHHCCCHHEEEHHHHHHHHCCCCCCHHHHHHHHHCCCEECHHH
IERLMRVMGLKAIQKRKFKRTTNSDNNLPLKNNLLKRNFSVTQPDKVWVSDITYIPTKEG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECEEECCCCCC
WLYLSVVIDLYSRRVVGWSMDNHMTKRLVIDALEMAVLNRNPSRGLIFHSDRGSQYASHD
CCHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
FQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKFVSLFNSNIFSKVNHYYL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKFIFFHFHLQYLLSTTEWKYPIVTFIISYKLNGKLSLAGFYFKNKNILKI
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCEEEEEEEEEECCCEECC
>Mature Secondary Structure
MYPGQDITAGLKRKPGKRELTNKKLKLKIAEIYWQTRGRYGSPRIHKQLKKEGYHYNIKR
CCCCCCCHHHHHCCCCCHHHCCCHHEEEHHHHHHHHCCCCCCHHHHHHHHHCCCEECHHH
IERLMRVMGLKAIQKRKFKRTTNSDNNLPLKNNLLKRNFSVTQPDKVWVSDITYIPTKEG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECEEECCCCCC
WLYLSVVIDLYSRRVVGWSMDNHMTKRLVIDALEMAVLNRNPSRGLIFHSDRGSQYASHD
CCHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHH
FQKTLWKYGIISSMSRKGDCWDNAVAESFFATLKTELIFHNKFVSLFNSNIFSKVNHYYL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKFIFFHFHLQYLLSTTEWKYPIVTFIISYKLNGKLSLAGFYFKNKNILKI
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCEEEEEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]