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The map label for this gene is nadB1 [H]

Identifier: 220918794

GI number: 220918794

Start: 4125893

End: 4127500

Strand: Direct

Name: nadB1 [H]

Synonym: A2cp1_3706

Alternate gene names: 220918794

Gene position: 4125893-4127500 (Clockwise)

Preceding gene: 220918790

Following gene: 220918803

Centisome position: 82.04

GC content: 71.58

Gene sequence:

>1608_bases
ATGACCACACTGCCTGCACGAGAGAACGTGGACTTCCTGGTCCTTGGTGGTGGTGTCGCGGGGCTGACCTTCGCGCTCGA
GGCGGCCGATCACGGATCGGTGCTGGTGCTGACGAAGCGGCAGCGCTCGGAGGGCTCGACGCAGTACGCGCAGGGGGGCA
TCGCGGGCGTGCTGGGCGCGGACGACGCGCCGGAGCTGCACGTCCAGGACACCCTGGTCGCCGGCGCCGGGCTGTGCAAG
CGCGAGGCGGTCGAGGTCACGGTCCGCGAGGGACCGGACCGGCTGCGCTGGCTCATCGGCATCGGCGTCGAGTTCGACCG
CGAGGCCCCCGACAAGCTCCACCTCACCCGCGAGGGCGGCCACTCGCGGCGTCGCATCGCGCACGCGAAGGACACCACCG
GCCGCGAGGTGGAGCGGGCGCTGCTCGCCGCCTGCGACGCGAAGGGCATCCGGATCGTCGAGGACCAGGTCGCGATCGAC
GTCATCACGAGCGGCAAGCTCGGCCTGGGCGGCCCGAACCGCGCGCTCGGCGCCTACGTGCTCGACCGCGCCTCCGGCGA
CATCACCACGGTGACGGCGGGCGTGACGGTGCTCGCCACCGGCGGCGGCGGGAAGGTCTACCTCTACACCTCGAACCCGG
ACGTCGCGACGGGCGACGGGGTGGCGATGGCGTACCGGGCCGGCGCGACCATCGCGAACATGGAGTTCTTCCAGTTCCAC
CCCACCTGCCTGTTCCACCCGCAGGCGAAGAGCTTCCTCATCTCCGAGGCGTGCCGCGGCGAGGGCGGCATCCTCCGCAA
CGGCGCCGGCGAGGCGTTCATGTCGCGCTACGATCCGCGCAAGGAGCTGGCGCCGCGCGACATCGTGGCCCGCTCCATCG
ACGCCGAGATGAAGCGGCGCGGCGACGAGAGCGCGTTCCTCGACATGACGCACCTGCCGAAGAGCTTCCTCATCGAGCAC
TTCCCGAACATCTACGCCACCTGCAAGGAGTTCGGGATCGACATGGCGGTGCAGCCGATCCCGGTGGTGCCGGCGGCGCA
CTACATGTGCGGCGGCGTGGTGACCGACCTCATGGGCCGCACCTCGCTGCCGCGGCTGTTCGCGATCGGCGAGACGTCCT
GCACCGGCCTGCACGGCGCGAACCGGCTCGCCTCCAACTCGCTGCTGGAGGGGCTGGTGTTCGGGCGCCGCGCCGCGCTG
AGCGCCGTGGACGAGCTCGGCCACGTGGGCGGCACGCTCCCGACGATCCCGGACTGGAACCCCGGGGCCGCGCTCGCGCC
CGAGGAAGGCGTGGTGGTCACGCACAACTGGGACGAGGTCCGCCGGCTGATGTGGAACTACGTCGGCATCGTCCGCACGC
AGAAGCGCCTGGAGCGCGCGCGCACCCGGCTCGCGCTGCTGCGCGCGGAGATCCGCGAGTACTACTGGGAGTACCGGCTC
ACCCCGGACCTGGTGGAGCTGCGGAACCTCGCCGACGTGGCGATGCTGATCGTGGAGTGCGCGCGGCAGCGCAAGGAGTC
GCGCGGCCTCCACTACCTGCTCGACCACCCGAAGCCCGACGACCGCTGGCTGCGCGACACGGTGATCACGCGCGGCGATC
TCGAGTGA

Upstream 100 bases:

>100_bases
ACCTGGCGAGGTAGGGACGGACGGACATCGTCGAAAAAGTTACCAGCAGCACGCTCGGCCGGACAACTTTATTCCCGGAG
CGCGTGCTACATCAAACGCC

Downstream 100 bases:

>100_bases
GCGGCCGCGCCGGTCCGCGCCCGGGCCCGCGCGCGCGGGCCCGCGGCGCGCCGCAGGCCGCCTACAGGTCGGGATCCGAC
TCGAGCCGCGACGGCTCGGG

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MTTLPARENVDFLVLGGGVAGLTFALEAADHGSVLVLTKRQRSEGSTQYAQGGIAGVLGADDAPELHVQDTLVAGAGLCK
REAVEVTVREGPDRLRWLIGIGVEFDREAPDKLHLTREGGHSRRRIAHAKDTTGREVERALLAACDAKGIRIVEDQVAID
VITSGKLGLGGPNRALGAYVLDRASGDITTVTAGVTVLATGGGGKVYLYTSNPDVATGDGVAMAYRAGATIANMEFFQFH
PTCLFHPQAKSFLISEACRGEGGILRNGAGEAFMSRYDPRKELAPRDIVARSIDAEMKRRGDESAFLDMTHLPKSFLIEH
FPNIYATCKEFGIDMAVQPIPVVPAAHYMCGGVVTDLMGRTSLPRLFAIGETSCTGLHGANRLASNSLLEGLVFGRRAAL
SAVDELGHVGGTLPTIPDWNPGAALAPEEGVVVTHNWDEVRRLMWNYVGIVRTQKRLERARTRLALLRAEIREYYWEYRL
TPDLVELRNLADVAMLIVECARQRKESRGLHYLLDHPKPDDRWLRDTVITRGDLE

Sequences:

>Translated_535_residues
MTTLPARENVDFLVLGGGVAGLTFALEAADHGSVLVLTKRQRSEGSTQYAQGGIAGVLGADDAPELHVQDTLVAGAGLCK
REAVEVTVREGPDRLRWLIGIGVEFDREAPDKLHLTREGGHSRRRIAHAKDTTGREVERALLAACDAKGIRIVEDQVAID
VITSGKLGLGGPNRALGAYVLDRASGDITTVTAGVTVLATGGGGKVYLYTSNPDVATGDGVAMAYRAGATIANMEFFQFH
PTCLFHPQAKSFLISEACRGEGGILRNGAGEAFMSRYDPRKELAPRDIVARSIDAEMKRRGDESAFLDMTHLPKSFLIEH
FPNIYATCKEFGIDMAVQPIPVVPAAHYMCGGVVTDLMGRTSLPRLFAIGETSCTGLHGANRLASNSLLEGLVFGRRAAL
SAVDELGHVGGTLPTIPDWNPGAALAPEEGVVVTHNWDEVRRLMWNYVGIVRTQKRLERARTRLALLRAEIREYYWEYRL
TPDLVELRNLADVAMLIVECARQRKESRGLHYLLDHPKPDDRWLRDTVITRGDLE
>Mature_534_residues
TTLPARENVDFLVLGGGVAGLTFALEAADHGSVLVLTKRQRSEGSTQYAQGGIAGVLGADDAPELHVQDTLVAGAGLCKR
EAVEVTVREGPDRLRWLIGIGVEFDREAPDKLHLTREGGHSRRRIAHAKDTTGREVERALLAACDAKGIRIVEDQVAIDV
ITSGKLGLGGPNRALGAYVLDRASGDITTVTAGVTVLATGGGGKVYLYTSNPDVATGDGVAMAYRAGATIANMEFFQFHP
TCLFHPQAKSFLISEACRGEGGILRNGAGEAFMSRYDPRKELAPRDIVARSIDAEMKRRGDESAFLDMTHLPKSFLIEHF
PNIYATCKEFGIDMAVQPIPVVPAAHYMCGGVVTDLMGRTSLPRLFAIGETSCTGLHGANRLASNSLLEGLVFGRRAALS
AVDELGHVGGTLPTIPDWNPGAALAPEEGVVVTHNWDEVRRLMWNYVGIVRTQKRLERARTRLALLRAEIREYYWEYRLT
PDLVELRNLADVAMLIVECARQRKESRGLHYLLDHPKPDDRWLRDTVITRGDLE

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=537, Percent_Identity=32.2160148975791, Blast_Score=215, Evalue=1e-55,
Organism=Escherichia coli, GI1788928, Length=523, Percent_Identity=52.9636711281071, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI1790597, Length=543, Percent_Identity=32.0441988950276, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1786942, Length=566, Percent_Identity=33.0388692579505, Blast_Score=217, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17550100, Length=561, Percent_Identity=31.0160427807487, Blast_Score=207, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17505833, Length=518, Percent_Identity=31.0810810810811, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71986328, Length=462, Percent_Identity=28.7878787878788, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322701, Length=527, Percent_Identity=31.3092979127135, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6322416, Length=544, Percent_Identity=31.4338235294118, Blast_Score=219, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320788, Length=484, Percent_Identity=27.6859504132231, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322511, Length=479, Percent_Identity=26.7223382045929, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17137288, Length=530, Percent_Identity=32.0754716981132, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24655642, Length=530, Percent_Identity=32.0754716981132, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24655647, Length=530, Percent_Identity=32.0754716981132, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24663005, Length=519, Percent_Identity=30.0578034682081, Blast_Score=185, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 58279; Mature: 58148

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLPARENVDFLVLGGGVAGLTFALEAADHGSVLVLTKRQRSEGSTQYAQGGIAGVLGA
CCCCCCCCCCCEEEECCCCEEEEEEEEECCCCCEEEEEECCCCCCCCHHHCCCEEEEECC
DDAPELHVQDTLVAGAGLCKREAVEVTVREGPDRLRWLIGIGVEFDREAPDKLHLTREGG
CCCCCEEEHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCEECCCCCCEEEEECCCC
HSRRRIAHAKDTTGREVERALLAACDAKGIRIVEDQVAIDVITSGKLGLGGPNRALGAYV
CCHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCCCCCCCHHHHHHH
LDRASGDITTVTAGVTVLATGGGGKVYLYTSNPDVATGDGVAMAYRAGATIANMEFFQFH
HCCCCCCEEEEEECEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCEEECCEEEEEC
PTCLFHPQAKSFLISEACRGEGGILRNGAGEAFMSRYDPRKELAPRDIVARSIDAEMKRR
CEEEECCCHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCHHHCCCHHHHHHHHHHHHHHC
GDESAFLDMTHLPKSFLIEHFPNIYATCKEFGIDMAVQPIPVVPAAHYMCGGVVTDLMGR
CCCCCEEEHHHCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
TSLPRLFAIGETSCTGLHGANRLASNSLLEGLVFGRRAALSAVDELGHVGGTLPTIPDWN
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGAALAPEEGVVVTHNWDEVRRLMWNYVGIVRTQKRLERARTRLALLRAEIREYYWEYRL
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TPDLVELRNLADVAMLIVECARQRKESRGLHYLLDHPKPDDRWLRDTVITRGDLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTLPARENVDFLVLGGGVAGLTFALEAADHGSVLVLTKRQRSEGSTQYAQGGIAGVLGA
CCCCCCCCCCEEEECCCCEEEEEEEEECCCCCEEEEEECCCCCCCCHHHCCCEEEEECC
DDAPELHVQDTLVAGAGLCKREAVEVTVREGPDRLRWLIGIGVEFDREAPDKLHLTREGG
CCCCCEEEHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCEECCCCCCEEEEECCCC
HSRRRIAHAKDTTGREVERALLAACDAKGIRIVEDQVAIDVITSGKLGLGGPNRALGAYV
CCHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCEEEEEEECCCCCCCCCCHHHHHHH
LDRASGDITTVTAGVTVLATGGGGKVYLYTSNPDVATGDGVAMAYRAGATIANMEFFQFH
HCCCCCCEEEEEECEEEEEECCCCEEEEEECCCCCCCCCCEEEEEECCCEEECCEEEEEC
PTCLFHPQAKSFLISEACRGEGGILRNGAGEAFMSRYDPRKELAPRDIVARSIDAEMKRR
CEEEECCCHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCHHHCCCHHHHHHHHHHHHHHC
GDESAFLDMTHLPKSFLIEHFPNIYATCKEFGIDMAVQPIPVVPAAHYMCGGVVTDLMGR
CCCCCEEEHHHCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
TSLPRLFAIGETSCTGLHGANRLASNSLLEGLVFGRRAALSAVDELGHVGGTLPTIPDWN
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PGAALAPEEGVVVTHNWDEVRRLMWNYVGIVRTQKRLERARTRLALLRAEIREYYWEYRL
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TPDLVELRNLADVAMLIVECARQRKESRGLHYLLDHPKPDDRWLRDTVITRGDLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]