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The map label for this gene is gtaB [H]

Identifier: 220918713

GI number: 220918713

Start: 4041564

End: 4042433

Strand: Direct

Name: gtaB [H]

Synonym: A2cp1_3621

Alternate gene names: 220918713

Gene position: 4041564-4042433 (Clockwise)

Preceding gene: 220918712

Following gene: 220918714

Centisome position: 80.36

GC content: 70.92

Gene sequence:

>870_bases
ATGGCGCCCAAGAAGATCCGCAAGGCCGTGATCCCCGCCGCGGGCCTCGGCACCCGGTTCCTCCCCGCCACCAAGGCGGT
CCCGAAGGAGCTGCTCCCGATCGTCGACACGCCGACCATCCAGTACATCGTGGCGGAGGCGGTCGCGGCCGGCGTCCGGG
ACATCATCCTCATCTGCGCGCGCGGCAAGGACTCGATCGTCGACCACTTCGACATCGCCGCGGAGCTGGAGGACCGGCTC
GAGAAGGCGGGCAAGCGCGAGCTGCGCAGGCAGATGCGCGAGATCGCCCAGATGGCGAACGTGCTCACCATCCGCCAGCA
GGAGCCGCTCGGGCTCGGGCACGCGGTGCTGTGCGCCCGCGACGCCATCGGCGACGAGCCGTTCGTGGTGATGCTGGGCG
ACGACATCATCGACGCGCAGGTGCCCGGCGCGAAGCAGCTCGCCGACTGCTGGGAGCGGCACGGGCTCGGCACGGTGGCG
CTCATGGAGGTGCCGCGCGAGGACACGCACATGTACGGCATCGCCGCGGGCCAGGCGATGGACCCGCGCACCGTGCGCAT
CGACCGGCTGGTCGAGAAGCCCAAGGCGGATCCGCCCTCGAACCTGGCGGTGATCGGCCGCTACGTCCTGCCCCCGCGCA
TCTTCGAGATCCTCGAGCGCGTGAAGCCGGGCGTGGGCGGCGAGATCCAGCTCACCGACGCGCTGGCGGTGCTGGCGCGC
GAGGAGGGGCTGCTGGGCTACCAGTTCGAGGGCGAGCGCTACGACGCGGGCGACCGCTTCGGCTACCTGAAGGCCAACAT
CCTCTACGCGATGAAGCGCCCCGAGCTGGCGGGGCCGCTGCGCGCGCTCATGAAGGAGCTCGTCAAGTGA

Upstream 100 bases:

>100_bases
AGACCGAGGCGGAGCGCGTGGAGCGGCCGAGATAGCGCCCGGCCCGGGGCGGTGCTCACCGGTGGTGCCTGGCCCGGGGC
CGGGCTAGATTGGCGGCACC

Downstream 100 bases:

>100_bases
ACCTCCGCCGCCTGGCCGCGGCCGCCGCGCTCGCGGCGGCGATGCCCTCGCTCGCCTACGTCCTCCACACCTCCGCCGTG
CTGCGGCGCATGGGCGAGAA

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MAPKKIRKAVIPAAGLGTRFLPATKAVPKELLPIVDTPTIQYIVAEAVAAGVRDIILICARGKDSIVDHFDIAAELEDRL
EKAGKRELRRQMREIAQMANVLTIRQQEPLGLGHAVLCARDAIGDEPFVVMLGDDIIDAQVPGAKQLADCWERHGLGTVA
LMEVPREDTHMYGIAAGQAMDPRTVRIDRLVEKPKADPPSNLAVIGRYVLPPRIFEILERVKPGVGGEIQLTDALAVLAR
EEGLLGYQFEGERYDAGDRFGYLKANILYAMKRPELAGPLRALMKELVK

Sequences:

>Translated_289_residues
MAPKKIRKAVIPAAGLGTRFLPATKAVPKELLPIVDTPTIQYIVAEAVAAGVRDIILICARGKDSIVDHFDIAAELEDRL
EKAGKRELRRQMREIAQMANVLTIRQQEPLGLGHAVLCARDAIGDEPFVVMLGDDIIDAQVPGAKQLADCWERHGLGTVA
LMEVPREDTHMYGIAAGQAMDPRTVRIDRLVEKPKADPPSNLAVIGRYVLPPRIFEILERVKPGVGGEIQLTDALAVLAR
EEGLLGYQFEGERYDAGDRFGYLKANILYAMKRPELAGPLRALMKELVK
>Mature_288_residues
APKKIRKAVIPAAGLGTRFLPATKAVPKELLPIVDTPTIQYIVAEAVAAGVRDIILICARGKDSIVDHFDIAAELEDRLE
KAGKRELRRQMREIAQMANVLTIRQQEPLGLGHAVLCARDAIGDEPFVVMLGDDIIDAQVPGAKQLADCWERHGLGTVAL
MEVPREDTHMYGIAAGQAMDPRTVRIDRLVEKPKADPPSNLAVIGRYVLPPRIFEILERVKPGVGGEIQLTDALAVLARE
EGLLGYQFEGERYDAGDRFGYLKANILYAMKRPELAGPLRALMKELVK

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=280, Percent_Identity=26.4285714285714, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI11761619, Length=280, Percent_Identity=26.4285714285714, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787488, Length=290, Percent_Identity=43.7931034482759, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1788355, Length=294, Percent_Identity=41.4965986394558, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1790224, Length=236, Percent_Identity=29.6610169491525, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320148, Length=265, Percent_Identity=27.1698113207547, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 31755; Mature: 31623

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPKKIRKAVIPAAGLGTRFLPATKAVPKELLPIVDTPTIQYIVAEAVAAGVRDIILICA
CCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEE
RGKDSIVDHFDIAAELEDRLEKAGKRELRRQMREIAQMANVLTIRQQEPLGLGHAVLCAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
DAIGDEPFVVMLGDDIIDAQVPGAKQLADCWERHGLGTVALMEVPREDTHMYGIAAGQAM
HHCCCCCEEEEECCCEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCC
DPRTVRIDRLVEKPKADPPSNLAVIGRYVLPPRIFEILERVKPGVGGEIQLTDALAVLAR
CCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
EEGLLGYQFEGERYDAGDRFGYLKANILYAMKRPELAGPLRALMKELVK
HCCCEEEEECCCEECCCCCCCHHHHHEEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
APKKIRKAVIPAAGLGTRFLPATKAVPKELLPIVDTPTIQYIVAEAVAAGVRDIILICA
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEE
RGKDSIVDHFDIAAELEDRLEKAGKRELRRQMREIAQMANVLTIRQQEPLGLGHAVLCAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
DAIGDEPFVVMLGDDIIDAQVPGAKQLADCWERHGLGTVALMEVPREDTHMYGIAAGQAM
HHCCCCCEEEEECCCEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCC
DPRTVRIDRLVEKPKADPPSNLAVIGRYVLPPRIFEILERVKPGVGGEIQLTDALAVLAR
CCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
EEGLLGYQFEGERYDAGDRFGYLKANILYAMKRPELAGPLRALMKELVK
HCCCEEEEECCCEECCCCCCCHHHHHEEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]