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The map label for this gene is 220918282

Identifier: 220918282

GI number: 220918282

Start: 3527644

End: 3528702

Strand: Direct

Name: 220918282

Synonym: A2cp1_3185

Alternate gene names: NA

Gene position: 3527644-3528702 (Clockwise)

Preceding gene: 220918280

Following gene: 220918284

Centisome position: 70.14

GC content: 80.17

Gene sequence:

>1059_bases
ATGGCCCCCTCCCTCGTGATCTACGGCGCCTACGGGTACACCGGCGAGCTGGTCGCGCGCGAGGCGGCCGCCCGCGGCCT
GCCGGTGGTGCTCGCGGGCCGGGACTCGGAGCGCCTGGCCCGCCTCGGCCGCGCGCTCGGCCGCCCGTGGCGCGCGTTCC
CGCTCACCGACCCCGAGGCGCTCCGGGCCGGGCTGCAGGATGCGGGCGCGGTGCTGCATTGCGCCGGCCCCTACGTGGAC
ACCTGGCGGCCCATGGCCGAGGCGTGCCTCGAGCTCCGCGTGCACTACCTCGATCTCGCCGGCGAGGCCGCGGTGTACCG
CGCGCTCGCCGTCATGGGGCTCCACGCGGAGCGGGCCGGCGTGATGCTGCTCTCCGGCGCCGGGTTCGACGTGGTGCCCA
CCGACTGCCTCGCCGCGCACGTGGCCCGGCGCCTCCCCGGCGCCGTCCGCATCGCGATCGCGATCGACGCGCTCGGCCGC
CTCTCGCGCGGCACGGCGCGCACCGTGATGGCGCACGCGGGCGACGCCGACGCCCGGGAGCTGAACCCGCACCAGCCCGC
CGCCCGGAGGTTCGACCTCGGGTCCGGCCGCCTCGAGGCGGTGCAGGTGCCGTGGCCCGAGCGCGTCGCGGTGCCGCGCT
CGACCGGCATCCAGGACGTGGCGGTGTACCTGTGCGCCTCGCAGGCGCGGCGCCTCCTGCTCCGCGCCGTCCCGGCCGTC
GCGCCGCTGCTGGCGCTCCCGGGCGCGCGGGCGCTCGCGGTGCGCCTCCTCTCCGGCGGCGCCGCGGGCCCGGACGCCGA
GGCCCGCGCGCGCGGCCGGAGCCGCGTGTACGCCGAGGCGGTGGACGCGGCCGGCGCACGGGCGGCGTCGCGCCTGGCGC
TGCCCGAGGGCTACGCGTTCACGGCGCACGCCGCGGTGGAGATCGCCGCGCGCGCGCTCGCCGGCTACGCGCCGCCGGGC
TGGCACACCCCGGCGTCCGCCTACGGCCCCGACCTCGTGACCGCGCTCCCGGGCGTGACGCTCGAGGACCTGCCGCTCGC
GCGCCCCGCGAGCCCCTAG

Upstream 100 bases:

>100_bases
CGAGGAGAGGTCGAGCCACAGCCCGCCGTCGCGGGGGATCCACCGGAGAGGTGCCATGATTCCGCATTCTACCCGGGAGA
TCGCTGCTAGGCTCCGCGCC

Downstream 100 bases:

>100_bases
CCCTCCCGGCCTCGCCCGAGCGTCCGCAGCGCCGCGAGCCACAGGCGCGCCTCGCGCCGGCCCAGCCGCGCCCGGCGCAG
CGCGGCGGTGAGATCGCGGA

Product: Saccharopine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAPSLVIYGAYGYTGELVAREAAARGLPVVLAGRDSERLARLGRALGRPWRAFPLTDPEALRAGLQDAGAVLHCAGPYVD
TWRPMAEACLELRVHYLDLAGEAAVYRALAVMGLHAERAGVMLLSGAGFDVVPTDCLAAHVARRLPGAVRIAIAIDALGR
LSRGTARTVMAHAGDADARELNPHQPAARRFDLGSGRLEAVQVPWPERVAVPRSTGIQDVAVYLCASQARRLLLRAVPAV
APLLALPGARALAVRLLSGGAAGPDAEARARGRSRVYAEAVDAAGARAASRLALPEGYAFTAHAAVEIAARALAGYAPPG
WHTPASAYGPDLVTALPGVTLEDLPLARPASP

Sequences:

>Translated_352_residues
MAPSLVIYGAYGYTGELVAREAAARGLPVVLAGRDSERLARLGRALGRPWRAFPLTDPEALRAGLQDAGAVLHCAGPYVD
TWRPMAEACLELRVHYLDLAGEAAVYRALAVMGLHAERAGVMLLSGAGFDVVPTDCLAAHVARRLPGAVRIAIAIDALGR
LSRGTARTVMAHAGDADARELNPHQPAARRFDLGSGRLEAVQVPWPERVAVPRSTGIQDVAVYLCASQARRLLLRAVPAV
APLLALPGARALAVRLLSGGAAGPDAEARARGRSRVYAEAVDAAGARAASRLALPEGYAFTAHAAVEIAARALAGYAPPG
WHTPASAYGPDLVTALPGVTLEDLPLARPASP
>Mature_351_residues
APSLVIYGAYGYTGELVAREAAARGLPVVLAGRDSERLARLGRALGRPWRAFPLTDPEALRAGLQDAGAVLHCAGPYVDT
WRPMAEACLELRVHYLDLAGEAAVYRALAVMGLHAERAGVMLLSGAGFDVVPTDCLAAHVARRLPGAVRIAIAIDALGRL
SRGTARTVMAHAGDADARELNPHQPAARRFDLGSGRLEAVQVPWPERVAVPRSTGIQDVAVYLCASQARRLLLRAVPAVA
PLLALPGARALAVRLLSGGAAGPDAEARARGRSRVYAEAVDAAGARAASRLALPEGYAFTAHAAVEIAARALAGYAPPGW
HTPASAYGPDLVTALPGVTLEDLPLARPASP

Specific function: Involved in the reduction of the double bond between C-4 and C-5 during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis [H]

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=166, Percent_Identity=29.5180722891566, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 36649; Mature: 36517

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSLVIYGAYGYTGELVAREAAARGLPVVLAGRDSERLARLGRALGRPWRAFPLTDPEA
CCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCEECCCCCHHH
LRAGLQDAGAVLHCAGPYVDTWRPMAEACLELRVHYLDLAGEAAVYRALAVMGLHAERAG
HHHCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
VMLLSGAGFDVVPTDCLAAHVARRLPGAVRIAIAIDALGRLSRGTARTVMAHAGDADARE
EEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCHHHHHEEECCCCCHHH
LNPHQPAARRFDLGSGRLEAVQVPWPERVAVPRSTGIQDVAVYLCASQARRLLLRAVPAV
CCCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
APLLALPGARALAVRLLSGGAAGPDAEARARGRSRVYAEAVDAAGARAASRLALPEGYAF
HHHHHCCCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TAHAAVEIAARALAGYAPPGWHTPASAYGPDLVTALPGVTLEDLPLARPASP
EHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
APSLVIYGAYGYTGELVAREAAARGLPVVLAGRDSERLARLGRALGRPWRAFPLTDPEA
CCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCEECCCCCHHH
LRAGLQDAGAVLHCAGPYVDTWRPMAEACLELRVHYLDLAGEAAVYRALAVMGLHAERAG
HHHCHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
VMLLSGAGFDVVPTDCLAAHVARRLPGAVRIAIAIDALGRLSRGTARTVMAHAGDADARE
EEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCHHHHHEEECCCCCHHH
LNPHQPAARRFDLGSGRLEAVQVPWPERVAVPRSTGIQDVAVYLCASQARRLLLRAVPAV
CCCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
APLLALPGARALAVRLLSGGAAGPDAEARARGRSRVYAEAVDAAGARAASRLALPEGYAF
HHHHHCCCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TAHAAVEIAARALAGYAPPGWHTPASAYGPDLVTALPGVTLEDLPLARPASP
EHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]