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The map label for this gene is ahpF [C]

Identifier: 220917996

GI number: 220917996

Start: 3205421

End: 3206092

Strand: Direct

Name: ahpF [C]

Synonym: A2cp1_2897

Alternate gene names: 220917996

Gene position: 3205421-3206092 (Clockwise)

Preceding gene: 220917992

Following gene: 220917997

Centisome position: 63.73

GC content: 73.21

Gene sequence:

>672_bases
ATGGCGCTCATCGGGAAGGACGACGCGGAGCAGATCCGCGCGGAGCTGGAAGGCGCGCTGCAGGGCGACGTCAAGCTGAC
GCTCGTCGGCCCGAGCGCCCTCGCCCCGCCGGCGCGGGATCTCACCCCGCAGATCCGCCAGCTGCTGGAGGAGGTGGCGG
CGCTGTCGCCCAAGCTCGCGTTCGAGTACCTCGACCTGCCCACCCCCGAACAGCGCGAGGCGCTCGGGCTGGCGACGGAC
GAGGCCGGTCCGCTCACGCTCCTCTCCGGCGCGGCGCGCGGGCGCGTGCGCTACCTCGGGGCGCCCGCCGGCCACGAGTT
CCCGAACCTCGTGAACGGCATCATCGACGTGTCGCGCGGCGAGTCCGGGCTGTCGCCCGCCTCGCGCGAGGCGCTCGCCC
GGATCTCACGGCCGGTGCACATCAAGGTGTTCTTCACGCCCACTTGACCGTACTGCCCCCAGGCGGCCGGTCTGGCCCAT
GCCATCGCGGTGGAGAGCGCCCACGTCGTCGCCGACGCCATCGAGGCCCAGGAGTTCCCCGACCTCGCGGCGCGGTACCA
GGTCATGGGCGTGCCCAAGACGATCGTGAACGACGTCGAGGAGTTCGTCGGCGCCGTCCCGGAGGACGAGTTCGTGGCGC
ACGTGCTCCGGGCGGCCGGCGTGCCGGCCTGA

Upstream 100 bases:

>100_bases
CGCCCGGCGCGGACCACCGCCGAGCGCCCGGGCGCGTGCGCCGGCGCCGGCCCGGCGCTAGGTATGGACGCTCGCGGCCC
GGAGGCCGCGCGGAGGCCGC

Downstream 100 bases:

>100_bases
CCGGCCGAGGACGGCGCCCGCGGCGCGACGCTCGCGCACCCTCGCGCGTGCCGCCTTGGTGCGTGCCGCGATCGCGCGTC
GCGCGGTCGCGCGGGTGGCC

Product: glutaredoxin-like domain-containing protein

Products: an alcohol; H2O; NAD [C]

Alternate protein names: Glutaredoxin-Like Domain-Containing Protein; Glutaredoxin-Like Protein; FAD-Dependent Pyridine Nucleotide-Disulphide Oxidoreductase; Protein-Disulfide Oxidoreductase; Glutaredoxin-Related Protein; AhpF Family Protein/Thioredoxin Reductase; Protein Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase F Subunit; Redoxin-Like Protein; Alkyl Hydroperoxide Reductase Subunit F Related Protein; Dehydrogenase Selenocysteine-Containing; Dehydrogenase Selenocysteine-Containing Protein; Thioredoxin Reductase; Glutaredoxin Related Protein

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MALIGKDDAEQIRAELEGALQGDVKLTLVGPSALAPPARDLTPQIRQLLEEVAALSPKLAFEYLDLPTPEQREALGLATD
EAGPLTLLSGAARGRVRYLGAPAGHEFPNLVNGIIDVSRGESGLSPASREALARISRPVHIKVFFTPTUPYCPQAAGLAH
AIAVESAHVVADAIEAQEFPDLAARYQVMGVPKTIVNDVEEFVGAVPEDEFVAHVLRAAGVPA

Sequences:

>Translated_223_residues
MALIGKDDAEQIRAELEGALQGDVKLTLVGPSALAPPARDLTPQIRQLLEEVAALSPKLAFEYLDLPTPEQREALGLATD
EAGPLTLLSGAARGRVRYLGAPAGHEFPNLVNGIIDVSRGESGLSPASREALARISRPVHIKVFFTPT*PYCPQAAGLAH
AIAVESAHVVADAIEAQEFPDLAARYQVMGVPKTIVNDVEEFVGAVPEDEFVAHVLRAAGVPA
>Mature_222_residues
ALIGKDDAEQIRAELEGALQGDVKLTLVGPSALAPPARDLTPQIRQLLEEVAALSPKLAFEYLDLPTPEQREALGLATDE
AGPLTLLSGAARGRVRYLGAPAGHEFPNLVNGIIDVSRGESGLSPASREALARISRPVHIKVFFTPT*PYCPQAAGLAHA
IAVESAHVVADAIEAQEFPDLAARYQVMGVPKTIVNDVEEFVGAVPEDEFVAHVLRAAGVPA

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.4.- [C]

Molecular weight: Translated: 23402; Mature: 23271

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIGKDDAEQIRAELEGALQGDVKLTLVGPSALAPPARDLTPQIRQLLEEVAALSPKLA
CCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCCCCHHHHHHHHHHHHCCHHHH
FEYLDLPTPEQREALGLATDEAGPLTLLSGAARGRVRYLGAPAGHEFPNLVNGIIDVSRG
HHHCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCC
ESGLSPASREALARISRPVHIKVFFTPTPYCPQAAGLAHAIAVESAHVVADAIEAQEFPD
CCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
LAARYQVMGVPKTIVNDVEEFVGAVPEDEFVAHVLRAAGVPA
HHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALIGKDDAEQIRAELEGALQGDVKLTLVGPSALAPPARDLTPQIRQLLEEVAALSPKLA
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCCCCCHHHHHHHHHHHHCCHHHH
FEYLDLPTPEQREALGLATDEAGPLTLLSGAARGRVRYLGAPAGHEFPNLVNGIIDVSRG
HHHCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCC
ESGLSPASREALARISRPVHIKVFFTPTPYCPQAAGLAHAIAVESAHVVADAIEAQEFPD
CCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
LAARYQVMGVPKTIVNDVEEFVGAVPEDEFVAHVLRAAGVPA
HHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ROOH; Proton; NADH [C]

Specific reaction: ROOH + Proton + NADH = an alcohol + H2O + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA