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The map label for this gene is argD [H]

Identifier: 220917977

GI number: 220917977

Start: 3178494

End: 3179699

Strand: Reverse

Name: argD [H]

Synonym: A2cp1_2878

Alternate gene names: 220917977

Gene position: 3179699-3178494 (Counterclockwise)

Preceding gene: 220917978

Following gene: 220917976

Centisome position: 63.22

GC content: 74.54

Gene sequence:

>1206_bases
ATGACACGCAACGAGTCGATCGCCCAGCGCGCGCAGCAGGTGCTCACGCCCAACTACCGGCAGCAGCCGGTGGCCATCGC
GCGCGGCGAGGGCGTCCGCGTCTGGGACGCCGACGGCAACGAGTACCTGGACTTCCTCGGCGGCGTGGCGGTGGACGCGC
TCGGCCACTGCCACCCCGCGCTGGTGAAGGCGCTCGAGGAGCAGGCCCGCACCGTCTGGCACGTGTCGAACCACTACTAC
ATCCCGCGCCAGGTCGAGCTCGCCGAGGCGCTGCTGGCGGTCACGCCCTGGGCGTCGCGGGCGTTCTTCTGCAACAGCGG
CGGCGAGGCGAACGAGGCGGTGCTGAAGCTCGCGCGCAAGTTCCACCACGACCGCGGCCACCCCGAGCGGAACGTCATCG
TCTCCTGCCACGACTCGTTCCACGGTCGGTCGCTCTTCACGGTCACCGTGGGCGGCCAGCCGAAGTACCAGGCCGGCTTC
GCGCCGCTCGTCCCCGGCGTCCGCCACGTGAAGTACGGCGACCTCGCCGCGCTCGAGGCGGCGCTCGACGACACCGTGGC
GGCGTTCATGGTCGAGCCGATCATGGGCGAGTCCGGCGTGGTCCCGCCGCCGGAGGGCTACCTGCGCGCCGTGCGCGAGC
TGACGCGGAAGAAGGGCGTGCTGCTGTGCCTCGACGAGGTGCAGACCGGCATGGGCCGCACCGGCAAGTTCTGGGCGCAC
GAGTGGGAGGGGATCACGCCCGACCTCATGTCCAGCGCCAAGGCGCTCGGCGGCGGGTTCCCCATCGGCGCGATGCTCGC
CACCGAGGAGGTCGGCCAGCACCTCACCCCCGGCAGCCACGGCACCACCTACGGCGGCAACCCGCTCGCCTGCGCGGTGG
CCCTGGCCGTGCTGGCCGAGCTGCGGGGCGGCGTGCTGGAGCGCTCGCGCGAGGTCGCGGCGCGGCTCCGCGCGGGGCTG
GAGGCGCTCGCCTCCGGCGGCCGGGTGGCACGGGTCCGCGGCAGGGGCATGCTGCTCGGCGTGATCGTGCAGGGGGTCGC
GGCCGCCGAGGTGATGAAGGCCGCCCGCGCGCAGGGGCTCCTCGTGAACGCCATCGGCGACGACGTGCTGCGCCTGGCCC
CGCCGCTCACCCTGACCGCCGCCGAGGCCGACCTGGCCGTGGAGCGGCTCGGCGCGGCCCTGGCGGCGGCGCCCGCGAAG
CCCTGA

Upstream 100 bases:

>100_bases
GACCTGTCGCGCTACATCCTGTGAGGCGCACGCCCGGGCGCGCCCGACCGGGCGCTCGCGGATCTGGAACTCTCCGCCGC
CCGGCTGCTATAAGCGCGGA

Downstream 100 bases:

>100_bases
GAGGACCCCATGGCCACCTCGCCCCGCGAGAAGCGCGACTTCCTCCGCATCACCGACCTGGATCGCTCGGAGCTGCTCGA
GCTGGTGGAGCGCGCCGCGG

Product: acetylornithine and succinylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTRNESIAQRAQQVLTPNYRQQPVAIARGEGVRVWDADGNEYLDFLGGVAVDALGHCHPALVKALEEQARTVWHVSNHYY
IPRQVELAEALLAVTPWASRAFFCNSGGEANEAVLKLARKFHHDRGHPERNVIVSCHDSFHGRSLFTVTVGGQPKYQAGF
APLVPGVRHVKYGDLAALEAALDDTVAAFMVEPIMGESGVVPPPEGYLRAVRELTRKKGVLLCLDEVQTGMGRTGKFWAH
EWEGITPDLMSSAKALGGGFPIGAMLATEEVGQHLTPGSHGTTYGGNPLACAVALAVLAELRGGVLERSREVAARLRAGL
EALASGGRVARVRGRGMLLGVIVQGVAAAEVMKAARAQGLLVNAIGDDVLRLAPPLTLTAAEADLAVERLGAALAAAPAK
P

Sequences:

>Translated_401_residues
MTRNESIAQRAQQVLTPNYRQQPVAIARGEGVRVWDADGNEYLDFLGGVAVDALGHCHPALVKALEEQARTVWHVSNHYY
IPRQVELAEALLAVTPWASRAFFCNSGGEANEAVLKLARKFHHDRGHPERNVIVSCHDSFHGRSLFTVTVGGQPKYQAGF
APLVPGVRHVKYGDLAALEAALDDTVAAFMVEPIMGESGVVPPPEGYLRAVRELTRKKGVLLCLDEVQTGMGRTGKFWAH
EWEGITPDLMSSAKALGGGFPIGAMLATEEVGQHLTPGSHGTTYGGNPLACAVALAVLAELRGGVLERSREVAARLRAGL
EALASGGRVARVRGRGMLLGVIVQGVAAAEVMKAARAQGLLVNAIGDDVLRLAPPLTLTAAEADLAVERLGAALAAAPAK
P
>Mature_400_residues
TRNESIAQRAQQVLTPNYRQQPVAIARGEGVRVWDADGNEYLDFLGGVAVDALGHCHPALVKALEEQARTVWHVSNHYYI
PRQVELAEALLAVTPWASRAFFCNSGGEANEAVLKLARKFHHDRGHPERNVIVSCHDSFHGRSLFTVTVGGQPKYQAGFA
PLVPGVRHVKYGDLAALEAALDDTVAAFMVEPIMGESGVVPPPEGYLRAVRELTRKKGVLLCLDEVQTGMGRTGKFWAHE
WEGITPDLMSSAKALGGGFPIGAMLATEEVGQHLTPGSHGTTYGGNPLACAVALAVLAELRGGVLERSREVAARLRAGLE
ALASGGRVARVRGRGMLLGVIVQGVAAAEVMKAARAQGLLVNAIGDDVLRLAPPLTLTAAEADLAVERLGAALAAAPAKP

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=399, Percent_Identity=37.34335839599, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=31.2785388127854, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=39.9328859060403, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI37574042, Length=419, Percent_Identity=29.1169451073986, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=30.607476635514, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI226442705, Length=419, Percent_Identity=27.9236276849642, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI226442709, Length=384, Percent_Identity=29.1666666666667, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI188536080, Length=456, Percent_Identity=25.219298245614, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38679950, Length=456, Percent_Identity=25.219298245614, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38679946, Length=456, Percent_Identity=25.219298245614, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788044, Length=387, Percent_Identity=47.0284237726098, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1789759, Length=389, Percent_Identity=44.7300771208226, Blast_Score=320, Evalue=7e-89,
Organism=Escherichia coli, GI145693181, Length=381, Percent_Identity=40.9448818897638, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789016, Length=418, Percent_Identity=32.2966507177034, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787560, Length=399, Percent_Identity=34.8370927318296, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786349, Length=376, Percent_Identity=30.3191489361702, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786991, Length=400, Percent_Identity=29.25, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=38.3631713554987, Blast_Score=268, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=31.4814814814815, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI25144274, Length=261, Percent_Identity=40.6130268199234, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=28.7037037037037, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17541228, Length=454, Percent_Identity=28.4140969162996, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71981843, Length=174, Percent_Identity=34.4827586206897, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71992985, Length=125, Percent_Identity=32, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=391, Percent_Identity=38.1074168797954, Blast_Score=251, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=401, Percent_Identity=33.9152119700748, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6321456, Length=425, Percent_Identity=24.9411764705882, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357415, Length=397, Percent_Identity=38.0352644836272, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI28574759, Length=449, Percent_Identity=32.0712694877506, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI161085790, Length=454, Percent_Identity=31.7180616740088, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI21356575, Length=432, Percent_Identity=31.712962962963, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=25.4716981132075, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=25.4716981132075, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=25.4716981132075, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42503; Mature: 42372

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRNESIAQRAQQVLTPNYRQQPVAIARGEGVRVWDADGNEYLDFLGGVAVDALGHCHPA
CCCCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHH
LVKALEEQARTVWHVSNHYYIPRQVELAEALLAVTPWASRAFFCNSGGEANEAVLKLARK
HHHHHHHHHHHEEEECCEEECCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
FHHDRGHPERNVIVSCHDSFHGRSLFTVTVGGQPKYQAGFAPLVPGVRHVKYGDLAALEA
HHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHCCCCHHCCCCHHHHHHH
ALDDTVAAFMVEPIMGESGVVPPPEGYLRAVRELTRKKGVLLCLDEVQTGMGRTGKFWAH
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHCCCCCCCCCCC
EWEGITPDLMSSAKALGGGFPIGAMLATEEVGQHLTPGSHGTTYGGNPLACAVALAVLAE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
LRGGVLERSREVAARLRAGLEALASGGRVARVRGRGMLLGVIVQGVAAAEVMKAARAQGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCE
LVNAIGDDVLRLAPPLTLTAAEADLAVERLGAALAAAPAKP
EEEHHCCHHHHHCCCCEEEECHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TRNESIAQRAQQVLTPNYRQQPVAIARGEGVRVWDADGNEYLDFLGGVAVDALGHCHPA
CCCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHH
LVKALEEQARTVWHVSNHYYIPRQVELAEALLAVTPWASRAFFCNSGGEANEAVLKLARK
HHHHHHHHHHHEEEECCEEECCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
FHHDRGHPERNVIVSCHDSFHGRSLFTVTVGGQPKYQAGFAPLVPGVRHVKYGDLAALEA
HHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHCCCCHHCCCCHHHHHHH
ALDDTVAAFMVEPIMGESGVVPPPEGYLRAVRELTRKKGVLLCLDEVQTGMGRTGKFWAH
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHCCCCCCCCCCC
EWEGITPDLMSSAKALGGGFPIGAMLATEEVGQHLTPGSHGTTYGGNPLACAVALAVLAE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
LRGGVLERSREVAARLRAGLEALASGGRVARVRGRGMLLGVIVQGVAAAEVMKAARAQGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCE
LVNAIGDDVLRLAPPLTLTAAEADLAVERLGAALAAAPAKP
EEEHHCCHHHHHCCCCEEEECHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]