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The map label for this gene is argF [H]

Identifier: 220917976

GI number: 220917976

Start: 3177555

End: 3178484

Strand: Reverse

Name: argF [H]

Synonym: A2cp1_2877

Alternate gene names: 220917976

Gene position: 3178484-3177555 (Counterclockwise)

Preceding gene: 220917977

Following gene: 220917975

Centisome position: 63.2

GC content: 73.66

Gene sequence:

>930_bases
ATGGCCACCTCGCCCCGCGAGAAGCGCGACTTCCTCCGCATCACCGACCTGGATCGCTCGGAGCTGCTCGAGCTGGTGGA
GCGCGCCGCGGAGTGGAAGCTCCTCGGCAAGGGCGGCCCGCGGCCGCTGGAGCGGCGCACCGTCGGCCTGGTGTTCGAGA
AGGCCTCCACCCGCACCCGCGTCTCGTTCGAGGTGGCGGCGCACCAGCTCGGCGCGGGGTCGATCATGCTGTCGCCGCGC
GACACGCAGCTCGGGCGAGGAGAGCCGATCCGCGACACGGCCCGCGTGCTGTCGCGCTACCTGGACTGCCTGGTGGTGCG
CACGTACGGGCACGAGAAGATCGAGGAGATGGCGCGCTACGCCGGCGTGCCGGTGGTGAACGCGCTCACCGACGCGTCGC
ACCCGTGCCAGGTGCTGGCCGACCTGCTCACGGTCACCGAGCGCTTCGGCTCGGACGCGCTCACCAAGCCCGGCCTGCGG
GTGGCGTGGGTGGGCGACGGCAACAACATGGCCAACAGCTGGCTGGAGGCCTGCGTGCTGCTCGGGTTCGAGCTGCACCT
CGCCTGCCCGGCGGGCTACGACCCGGACCCGGCGCTGCTCGCCCGCGCGGCCGGGCGGGCGAAGGTGTTCCGCTCGCCGG
CCGAGGCGGTGGCGGGCGCGCACGTGGTGAACACCGACGTCTGGGCCAGCATGGGCCAGGAGCAGGAGGCGGAGGAGCGC
CGCCGCCGCTTCGAGGGGTTCATCGTGGACGGGCCGCTGATGGCGCGGGCGCGGCCGAACGCGGTGGTGCTCCACTGCCT
GCCGGCGCACCGCGGCGAGGAGATCACCGACGAGGTGCTGGAGGGCCCGCAGTCTGCGGTCTTCGACGAGGCCGAGAACC
GGCTGCACGCCCAGAAGGCCCTGCTCGAGCTGCTGCTCGCCGGCCGGTGA

Upstream 100 bases:

>100_bases
GGCCCCGCCGCTCACCCTGACCGCCGCCGAGGCCGACCTGGCCGTGGAGCGGCTCGGCGCGGCCCTGGCGGCGGCGCCCG
CGAAGCCCTGAGAGGACCCC

Downstream 100 bases:

>100_bases
CTGGCCGCCCGGACGGGCCCCGGCGCGTGTCCGGGGCCCGTGGGGCGGGCGCGCACGGAGCGGATTTGACCCCCTGCGGT
CCCGGTCGTTAATCTCGGGG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MATSPREKRDFLRITDLDRSELLELVERAAEWKLLGKGGPRPLERRTVGLVFEKASTRTRVSFEVAAHQLGAGSIMLSPR
DTQLGRGEPIRDTARVLSRYLDCLVVRTYGHEKIEEMARYAGVPVVNALTDASHPCQVLADLLTVTERFGSDALTKPGLR
VAWVGDGNNMANSWLEACVLLGFELHLACPAGYDPDPALLARAAGRAKVFRSPAEAVAGAHVVNTDVWASMGQEQEAEER
RRRFEGFIVDGPLMARARPNAVVLHCLPAHRGEEITDEVLEGPQSAVFDEAENRLHAQKALLELLLAGR

Sequences:

>Translated_309_residues
MATSPREKRDFLRITDLDRSELLELVERAAEWKLLGKGGPRPLERRTVGLVFEKASTRTRVSFEVAAHQLGAGSIMLSPR
DTQLGRGEPIRDTARVLSRYLDCLVVRTYGHEKIEEMARYAGVPVVNALTDASHPCQVLADLLTVTERFGSDALTKPGLR
VAWVGDGNNMANSWLEACVLLGFELHLACPAGYDPDPALLARAAGRAKVFRSPAEAVAGAHVVNTDVWASMGQEQEAEER
RRRFEGFIVDGPLMARARPNAVVLHCLPAHRGEEITDEVLEGPQSAVFDEAENRLHAQKALLELLLAGR
>Mature_308_residues
ATSPREKRDFLRITDLDRSELLELVERAAEWKLLGKGGPRPLERRTVGLVFEKASTRTRVSFEVAAHQLGAGSIMLSPRD
TQLGRGEPIRDTARVLSRYLDCLVVRTYGHEKIEEMARYAGVPVVNALTDASHPCQVLADLLTVTERFGSDALTKPGLRV
AWVGDGNNMANSWLEACVLLGFELHLACPAGYDPDPALLARAAGRAKVFRSPAEAVAGAHVVNTDVWASMGQEQEAEERR
RRFEGFIVDGPLMARARPNAVVLHCLPAHRGEEITDEVLEGPQSAVFDEAENRLHAQKALLELLLAGR

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=296, Percent_Identity=37.8378378378378, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI18105007, Length=275, Percent_Identity=29.8181818181818, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=40, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1790703, Length=324, Percent_Identity=39.8148148148148, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI2367364, Length=316, Percent_Identity=31.6455696202532, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193204318, Length=327, Percent_Identity=25.6880733944954, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=328, Percent_Identity=34.1463414634146, Blast_Score=206, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6322331, Length=318, Percent_Identity=27.0440251572327, Blast_Score=92, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24642586, Length=314, Percent_Identity=28.0254777070064, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 33959; Mature: 33828

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSPREKRDFLRITDLDRSELLELVERAAEWKLLGKGGPRPLERRTVGLVFEKASTRTR
CCCCCCCHHCCEEECCCCHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHEEECCCCCCE
VSFEVAAHQLGAGSIMLSPRDTQLGRGEPIRDTARVLSRYLDCLVVRTYGHEKIEEMARY
EHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AGVPVVNALTDASHPCQVLADLLTVTERFGSDALTKPGLRVAWVGDGNNMANSWLEACVL
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
LGFELHLACPAGYDPDPALLARAAGRAKVFRSPAEAVAGAHVVNTDVWASMGQEQEAEER
HHHHEEEECCCCCCCCHHHHHHHCCHHHHHCCHHHHHHCCHHCCHHHHHHCCCHHHHHHH
RRRFEGFIVDGPLMARARPNAVVLHCLPAHRGEEITDEVLEGPQSAVFDEAENRLHAQKA
HHHHCCEEECCCEEECCCCCEEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHH
LLELLLAGR
HHHHHHCCC
>Mature Secondary Structure 
ATSPREKRDFLRITDLDRSELLELVERAAEWKLLGKGGPRPLERRTVGLVFEKASTRTR
CCCCCCHHCCEEECCCCHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHEEECCCCCCE
VSFEVAAHQLGAGSIMLSPRDTQLGRGEPIRDTARVLSRYLDCLVVRTYGHEKIEEMARY
EHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AGVPVVNALTDASHPCQVLADLLTVTERFGSDALTKPGLRVAWVGDGNNMANSWLEACVL
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
LGFELHLACPAGYDPDPALLARAAGRAKVFRSPAEAVAGAHVVNTDVWASMGQEQEAEER
HHHHEEEECCCCCCCCHHHHHHHCCHHHHHCCHHHHHHCCHHCCHHHHHHCCCHHHHHHH
RRRFEGFIVDGPLMARARPNAVVLHCLPAHRGEEITDEVLEGPQSAVFDEAENRLHAQKA
HHHHCCEEECCCEEECCCCCEEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHH
LLELLLAGR
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA