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The map label for this gene is ilvE [H]

Identifier: 220917938

GI number: 220917938

Start: 3137741

End: 3138664

Strand: Reverse

Name: ilvE [H]

Synonym: A2cp1_2839

Alternate gene names: 220917938

Gene position: 3138664-3137741 (Counterclockwise)

Preceding gene: 220917943

Following gene: 220917937

Centisome position: 62.41

GC content: 78.9

Gene sequence:

>924_bases
ATGGCGACGCTGGTGAACCTGGACGGCGCGCTGGTCGCGCCGGCGGACGCGAAGGTCTCGGTGCTCGACCGCGGCTTCCT
GTACGGCGACAGCGTGTACGAGGTGGTGCGCACGTACGGTGGACGGCCGTTCGAGCTCGACGCGCACCTCGCGCGGCTGG
CGCGCTCGGCGGAGCGCACCGGGCTCGCGCCGCGATGGGACGGGCCGCGCACCGCGCGCGAGATCGCGCGCACGCTGGAG
GCCGCGCAGTCGCTGGGCGCGCCGCCCGCGCCCGCCGATGCTGCGCCGTGGAACGCGGGCGAGTGGTACGTGCGCGTGGT
GATGACGCGCGGCGCGGGGGAGATCGGGCTCGACCCCGCGCTCGCCGTGGATCCTCGGGCCGTGGTCATCGTCGCGCCGC
TCGCGGCGCCGCCGGCGCGCGCGTACGCCGAGGGCGTGACGGTGGCGATCGCGAGCGTGCGGCGCGCCTCACCCGCCGCG
GTGGACCCGGCCGCCAAGACCGGCGCGCACCTCTCGCACGTGCTCGCGGTGCGCGAGGCGCGCGCCGCGGGCGCGCACGA
GGCGCTCCTGCTCGACGACGCGGGGATGGTCACCGAGGGCTCGTCCTCCAACGTGTTCGCCGTCGTCGGCGGGCGCCTCC
GGACGCCGCCGCTGGCGGCCGGGATCCTGGAGGGCGTGACGCGGGGGGTGGTGCTCCGGCTCGCGCGCGAGGCGGGCGTG
CCGGTGGAGGAGGCGCCGCTCGGCGTGGACGCGCTGGAGTCGGCCGCCGAGGCCTTCCTCACCTCGACCATGCGCGAGAT
CCTGCCGGTGGTGCGGGTGGGCGCGCGGCCGATCGGGACCGGGCGGCCCGGCGCGGTCACCGAGCGGCTGCACCGGGCCT
TCCGCCGCCTCGCGGGCGGGCCGCCGGGCCTCGGCCCGCCGTGA

Upstream 100 bases:

>100_bases
AAAACGTCCACGATCACGCGGGCTTTTCACGGTGCGTCCGCGACCCGGACGCGGCGCGTCGGCCGCGCGCGCGGCGGCGA
CGGGGCGGTATGGTGAGGGC

Downstream 100 bases:

>100_bases
ACGTCCCGCCGCCGAGGGGTTCGCGCGCGGCGGCCGGCTCGTCGTAAGCTGGCGCGCTCATGGGCCGACTCCTCGCCGTG
CTCCTCGCCGTCGCGCTCGC

Product: class IV aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MATLVNLDGALVAPADAKVSVLDRGFLYGDSVYEVVRTYGGRPFELDAHLARLARSAERTGLAPRWDGPRTAREIARTLE
AAQSLGAPPAPADAAPWNAGEWYVRVVMTRGAGEIGLDPALAVDPRAVVIVAPLAAPPARAYAEGVTVAIASVRRASPAA
VDPAAKTGAHLSHVLAVREARAAGAHEALLLDDAGMVTEGSSSNVFAVVGGRLRTPPLAAGILEGVTRGVVLRLAREAGV
PVEEAPLGVDALESAAEAFLTSTMREILPVVRVGARPIGTGRPGAVTERLHRAFRRLAGGPPGLGPP

Sequences:

>Translated_307_residues
MATLVNLDGALVAPADAKVSVLDRGFLYGDSVYEVVRTYGGRPFELDAHLARLARSAERTGLAPRWDGPRTAREIARTLE
AAQSLGAPPAPADAAPWNAGEWYVRVVMTRGAGEIGLDPALAVDPRAVVIVAPLAAPPARAYAEGVTVAIASVRRASPAA
VDPAAKTGAHLSHVLAVREARAAGAHEALLLDDAGMVTEGSSSNVFAVVGGRLRTPPLAAGILEGVTRGVVLRLAREAGV
PVEEAPLGVDALESAAEAFLTSTMREILPVVRVGARPIGTGRPGAVTERLHRAFRRLAGGPPGLGPP
>Mature_306_residues
ATLVNLDGALVAPADAKVSVLDRGFLYGDSVYEVVRTYGGRPFELDAHLARLARSAERTGLAPRWDGPRTAREIARTLEA
AQSLGAPPAPADAAPWNAGEWYVRVVMTRGAGEIGLDPALAVDPRAVVIVAPLAAPPARAYAEGVTVAIASVRRASPAAV
DPAAKTGAHLSHVLAVREARAAGAHEALLLDDAGMVTEGSSSNVFAVVGGRLRTPPLAAGILEGVTRGVVLRLAREAGVP
VEEAPLGVDALESAAEAFLTSTMREILPVVRVGARPIGTGRPGAVTERLHRAFRRLAGGPPGLGPP

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=305, Percent_Identity=31.4754098360656, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787338, Length=256, Percent_Identity=25.390625, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 31634; Mature: 31502

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLVNLDGALVAPADAKVSVLDRGFLYGDSVYEVVRTYGGRPFELDAHLARLARSAERT
CCEEEECCCCEECCCCCEEEHHHCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHC
GLAPRWDGPRTAREIARTLEAAQSLGAPPAPADAAPWNAGEWYVRVVMTRGAGEIGLDPA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC
LAVDPRAVVIVAPLAAPPARAYAEGVTVAIASVRRASPAAVDPAAKTGAHLSHVLAVREA
EEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RAAGAHEALLLDDAGMVTEGSSSNVFAVVGGRLRTPPLAAGILEGVTRGVVLRLAREAGV
HHCCCCCEEEEECCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PVEEAPLGVDALESAAEAFLTSTMREILPVVRVGARPIGTGRPGAVTERLHRAFRRLAGG
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
PPGLGPP
CCCCCCC
>Mature Secondary Structure 
ATLVNLDGALVAPADAKVSVLDRGFLYGDSVYEVVRTYGGRPFELDAHLARLARSAERT
CEEEECCCCEECCCCCEEEHHHCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHC
GLAPRWDGPRTAREIARTLEAAQSLGAPPAPADAAPWNAGEWYVRVVMTRGAGEIGLDPA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC
LAVDPRAVVIVAPLAAPPARAYAEGVTVAIASVRRASPAAVDPAAKTGAHLSHVLAVREA
EEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RAAGAHEALLLDDAGMVTEGSSSNVFAVVGGRLRTPPLAAGILEGVTRGVVLRLAREAGV
HHCCCCCEEEEECCCCEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PVEEAPLGVDALESAAEAFLTSTMREILPVVRVGARPIGTGRPGAVTERLHRAFRRLAGG
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
PPGLGPP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]