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The map label for this gene is hldE [H]

Identifier: 220917891

GI number: 220917891

Start: 3085673

End: 3086683

Strand: Reverse

Name: hldE [H]

Synonym: A2cp1_2792

Alternate gene names: 220917891

Gene position: 3086683-3085673 (Counterclockwise)

Preceding gene: 220917892

Following gene: 220917890

Centisome position: 61.37

GC content: 76.26

Gene sequence:

>1011_bases
GTGCGCCGCCCCAGGGAACCCGAGCTGCCCTCGCTCGCCAGCCTCCTGCCCCGCTTCGCGGAGAGCGAGGTGGTCGTCGT
CGGCGACTTCGTGGCCGACGAGTACGTGTACGGCGAGACCGAGCGCATCAGCCGCGAGGCGCCGGTGCTCATCGTCCGGT
ACGAGTCGTCCGAGCTGAAGGCGGGCGGGGCGGGCAACGCCGCCGCGAACCTGGCCGCGCTCGGCGTGAAGGTCCGCGCC
GTCGGCGTGGTGGGCGACGACGGGCTGGGCAACGCGCTCCTCGAGGAGCTGACCGGACTGGGCGTGGACGTGGCGGGCAT
CCAGCGGGTGCCCGGACGAGAGACCGAGGCCAAGACCCGCATCCTCGCGGGCGGGCGCTCCACCCGGCGCCAGCAGATGA
TCCGCCTGGACCGCGCGCCGCGGGCGCCGCTCCCGGCCACCGCCGAGCGGCGGCTCGTGAAGGACCTGGAGCGGGCCGGG
CGCCGCGCGGGGACGGTGCTGGCGAGCGACTACGGATCGGGCGCGCTGGGCGCGGCCGCCATCGAGGCGCTCCGCCTGCT
GAAGCGCGGCGGTGTGCCGGTGTGCGTGGACTCCCGGTACAGCCTGCGCGCGTTCACCGGCCTCACGATGGTGAAGCCGA
ACGAGGTCGAGCTCGAGACCGCGTCGGGCGTGTCGCTGGCGCAGCCCGGCGGCCTGGAGAAGGCCGCGCGGACGCTGCTG
AAGCGCGTGGACTGCGACGTGCTGCTGGTGACGCGCGGGCGGAACGGGATGTCGGTGTTCCGCCGCGGCGCCCCGCCGGT
CCACGTGCCGGCGCACGGCAGCCAGGACGCGGTGGACGTGACCGGCGCGGGGGACACGGTGGCGGCCACCTTCAGCGCCG
GCCTCGCCGCCGGGGGTGATCCGGTCGCGGCGGCCCGGCTCGCGAACGTGGCCGGCTCGCTGGTGGTGCAGAAGGCGGGC
ACCGCCACCGTCTCGCGCGAGGAGCTCGCGGCGGAGCTGCTCCGGCCGTGA

Upstream 100 bases:

>100_bases
GCCGGCGCGCGCGTGTAGGGCACGCGGGCACCCGGCGCGGGCGGCGCGGCGGCGAGGTGCGCGATTGACGGGCGAAACCC
GCGCGCGGTAGGAAACGCGC

Downstream 100 bases:

>100_bases
GCCGCCTCGCCCGCAAGCGCGTCGCGCTCGAGGATCTCGCCGCGGTGCGCGCCCGCGCCTCCGCGGCCGGGCGCACGGTG
GCGCTCGCGAACGGCGTGTT

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRRPREPELPSLASLLPRFAESEVVVVGDFVADEYVYGETERISREAPVLIVRYESSELKAGGAGNAAANLAALGVKVRA
VGVVGDDGLGNALLEELTGLGVDVAGIQRVPGRETEAKTRILAGGRSTRRQQMIRLDRAPRAPLPATAERRLVKDLERAG
RRAGTVLASDYGSGALGAAAIEALRLLKRGGVPVCVDSRYSLRAFTGLTMVKPNEVELETASGVSLAQPGGLEKAARTLL
KRVDCDVLLVTRGRNGMSVFRRGAPPVHVPAHGSQDAVDVTGAGDTVAATFSAGLAAGGDPVAAARLANVAGSLVVQKAG
TATVSREELAAELLRP

Sequences:

>Translated_336_residues
MRRPREPELPSLASLLPRFAESEVVVVGDFVADEYVYGETERISREAPVLIVRYESSELKAGGAGNAAANLAALGVKVRA
VGVVGDDGLGNALLEELTGLGVDVAGIQRVPGRETEAKTRILAGGRSTRRQQMIRLDRAPRAPLPATAERRLVKDLERAG
RRAGTVLASDYGSGALGAAAIEALRLLKRGGVPVCVDSRYSLRAFTGLTMVKPNEVELETASGVSLAQPGGLEKAARTLL
KRVDCDVLLVTRGRNGMSVFRRGAPPVHVPAHGSQDAVDVTGAGDTVAATFSAGLAAGGDPVAAARLANVAGSLVVQKAG
TATVSREELAAELLRP
>Mature_336_residues
MRRPREPELPSLASLLPRFAESEVVVVGDFVADEYVYGETERISREAPVLIVRYESSELKAGGAGNAAANLAALGVKVRA
VGVVGDDGLGNALLEELTGLGVDVAGIQRVPGRETEAKTRILAGGRSTRRQQMIRLDRAPRAPLPATAERRLVKDLERAG
RRAGTVLASDYGSGALGAAAIEALRLLKRGGVPVCVDSRYSLRAFTGLTMVKPNEVELETASGVSLAQPGGLEKAARTLL
KRVDCDVLLVTRGRNGMSVFRRGAPPVHVPAHGSQDAVDVTGAGDTVAATFSAGLAAGGDPVAAARLANVAGSLVVQKAG
TATVSREELAAELLRP

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=315, Percent_Identity=37.7777777777778, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.-

Molecular weight: Translated: 34950; Mature: 34950

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPREPELPSLASLLPRFAESEVVVVGDFVADEYVYGETERISREAPVLIVRYESSELK
CCCCCCCCCCHHHHHHHHHCCCCEEEEECHHHCCHHCCCHHHHCCCCCEEEEEECCCCCC
AGGAGNAAANLAALGVKVRAVGVVGDDGLGNALLEELTGLGVDVAGIQRVPGRETEAKTR
CCCCCCHHHHHHHHCEEEEEEEEECCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCHHHHE
ILAGGRSTRRQQMIRLDRAPRAPLPATAERRLVKDLERAGRRAGTVLASDYGSGALGAAA
EEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHCEEEEECCCCCCHHHHH
IEALRLLKRGGVPVCVDSRYSLRAFTGLTMVKPNEVELETASGVSLAQPGGLEKAARTLL
HHHHHHHHHCCCCEEECCCCCEEHHCCEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHH
KRVDCDVLLVTRGRNGMSVFRRGAPPVHVPAHGSQDAVDVTGAGDTVAATFSAGLAAGGD
HHCCCCEEEEECCCCCHHHHHCCCCCEEECCCCCCCCEEECCCCCCEEHHHHHCCCCCCC
PVAAARLANVAGSLVVQKAGTATVSREELAAELLRP
HHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MRRPREPELPSLASLLPRFAESEVVVVGDFVADEYVYGETERISREAPVLIVRYESSELK
CCCCCCCCCCHHHHHHHHHCCCCEEEEECHHHCCHHCCCHHHHCCCCCEEEEEECCCCCC
AGGAGNAAANLAALGVKVRAVGVVGDDGLGNALLEELTGLGVDVAGIQRVPGRETEAKTR
CCCCCCHHHHHHHHCEEEEEEEEECCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCHHHHE
ILAGGRSTRRQQMIRLDRAPRAPLPATAERRLVKDLERAGRRAGTVLASDYGSGALGAAA
EEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHCEEEEECCCCCCHHHHH
IEALRLLKRGGVPVCVDSRYSLRAFTGLTMVKPNEVELETASGVSLAQPGGLEKAARTLL
HHHHHHHHHCCCCEEECCCCCEEHHCCEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHH
KRVDCDVLLVTRGRNGMSVFRRGAPPVHVPAHGSQDAVDVTGAGDTVAATFSAGLAAGGD
HHCCCCEEEEECCCCCHHHHHCCCCCEEECCCCCCCCEEECCCCCCEEHHHHHCCCCCCC
PVAAARLANVAGSLVVQKAGTATVSREELAAELLRP
HHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA