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The map label for this gene is gcvT [H]

Identifier: 220917813

GI number: 220917813

Start: 2993328

End: 2994410

Strand: Direct

Name: gcvT [H]

Synonym: A2cp1_2714

Alternate gene names: 220917813

Gene position: 2993328-2994410 (Clockwise)

Preceding gene: 220917812

Following gene: 220917814

Centisome position: 59.52

GC content: 72.76

Gene sequence:

>1083_bases
ATGGCCCTGCGCACGCCCCTTCACGACACGCACGTCCGCGCAGGCGCACGGATCGTGGAGTTCGCCGGCTGGCAGATGCC
GGTCCAGTACTCGGGCATCCTCGCCGAGCACGAGACCGTCCGCACCCGCGTCGGCCTGTTCGACGTCTCGCACATGGGCG
AGGTCGTGTTCCGCGGCCCGCGGGCGATCGCGGCGCTCGGCCGCCTGTTCACGAACGACCTCTCCAAGGTCGCCGACGGC
CAGGCGCAGTACGGCTGCCTGTGCCGCGACTCCGGCGGCATCGTGGACGACGTGGTGGTCTACCGCCGCTCCGCCGAGGA
CCTGCTCGTCTGCGTCAACGCCGGCAACCGGCAGAAGGACTTCGAGTGGCTGGCGGGCCACGCCGCCGGCGCCGACGTCC
GCAACGAGTCGGACGACTGGGCGCAGCTCGCGCTCCAGGGGCCGCTCGCCGCCCAGCTCCTGCAGCGGCTCACCACCGTG
AACCTCTCGGCGATGCGCAGCTACCGCTTCGGCGAGGGCGAGGTGGCCGGCGTCCGCTGCATCGTGGCCCGCACCGGCTA
CACCGGCGAGGACGGCTTCGAGCTGTTCTGCCGCTCCGACCTGGGCCCGCGGCTCTGGGACGCGCTCATGGAGGCGGGCG
TGCCCGAGCGCATCGCCCCCTGCGGCCTCGGCGCCCGCGACTCGCTGCGGCTCGAGATGGCGTACCGCCTCTACGGCTCG
GACATGGACGAGACCACCACGCCGCTCGAGGCCGGGCTGGCCTGGGTGGTGAAGCTCGACAAGGGCGACTTCATCGGCCG
CGAGGCGCTGCTCAAGCAGAAGGAGCAGGGGCTCTCGCGCAAGCTGGTGGGGTTCCAGCTCACCGACGCGGGCATCCCGC
GGCACGGCTACCCGGTGCTGCAGGACGGCCGCAAGGTGGGGGACGTGACCAGCGGGACCAAGAGCCCGTCGCTCGGCACC
GCCATCGGGCTCGCCTACGTGCCCCCCGCGCTCGCCGCCGAGGGCTCCACCTTCGCAGTCGAGATCCGCGGCCGGGCCGC
GGCGGCCAAGGCCGTGAAGACGCCGTTCTACACTCGGAAGTGA

Upstream 100 bases:

>100_bases
TGCTCGGGCGCGCCGGGCGCGAAATCCCGCGTCCTGGCGCGCTTGACCCCCGGGTCAGCCCCGATAGAATCCGCCCGCCC
ATCCCCACCCGAGGCGCCCA

Downstream 100 bases:

>100_bases
CGGAGACGACCATGGAAATCCCCGAGGACCTCAGGTACACGCGCGAGCACGAGTGGGCGCGCCGCAAGGGCAGCGCGATC
GTGGTCGGCATCACCGACTT

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MALRTPLHDTHVRAGARIVEFAGWQMPVQYSGILAEHETVRTRVGLFDVSHMGEVVFRGPRAIAALGRLFTNDLSKVADG
QAQYGCLCRDSGGIVDDVVVYRRSAEDLLVCVNAGNRQKDFEWLAGHAAGADVRNESDDWAQLALQGPLAAQLLQRLTTV
NLSAMRSYRFGEGEVAGVRCIVARTGYTGEDGFELFCRSDLGPRLWDALMEAGVPERIAPCGLGARDSLRLEMAYRLYGS
DMDETTTPLEAGLAWVVKLDKGDFIGREALLKQKEQGLSRKLVGFQLTDAGIPRHGYPVLQDGRKVGDVTSGTKSPSLGT
AIGLAYVPPALAAEGSTFAVEIRGRAAAAKAVKTPFYTRK

Sequences:

>Translated_360_residues
MALRTPLHDTHVRAGARIVEFAGWQMPVQYSGILAEHETVRTRVGLFDVSHMGEVVFRGPRAIAALGRLFTNDLSKVADG
QAQYGCLCRDSGGIVDDVVVYRRSAEDLLVCVNAGNRQKDFEWLAGHAAGADVRNESDDWAQLALQGPLAAQLLQRLTTV
NLSAMRSYRFGEGEVAGVRCIVARTGYTGEDGFELFCRSDLGPRLWDALMEAGVPERIAPCGLGARDSLRLEMAYRLYGS
DMDETTTPLEAGLAWVVKLDKGDFIGREALLKQKEQGLSRKLVGFQLTDAGIPRHGYPVLQDGRKVGDVTSGTKSPSLGT
AIGLAYVPPALAAEGSTFAVEIRGRAAAAKAVKTPFYTRK
>Mature_359_residues
ALRTPLHDTHVRAGARIVEFAGWQMPVQYSGILAEHETVRTRVGLFDVSHMGEVVFRGPRAIAALGRLFTNDLSKVADGQ
AQYGCLCRDSGGIVDDVVVYRRSAEDLLVCVNAGNRQKDFEWLAGHAAGADVRNESDDWAQLALQGPLAAQLLQRLTTVN
LSAMRSYRFGEGEVAGVRCIVARTGYTGEDGFELFCRSDLGPRLWDALMEAGVPERIAPCGLGARDSLRLEMAYRLYGSD
MDETTTPLEAGLAWVVKLDKGDFIGREALLKQKEQGLSRKLVGFQLTDAGIPRHGYPVLQDGRKVGDVTSGTKSPSLGTA
IGLAYVPPALAAEGSTFAVEIRGRAAAAKAVKTPFYTRK

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=363, Percent_Identity=36.6391184573003, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI257796258, Length=349, Percent_Identity=36.676217765043, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI24797151, Length=359, Percent_Identity=32.8690807799443, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI257796254, Length=358, Percent_Identity=33.2402234636872, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI257796256, Length=297, Percent_Identity=36.026936026936, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI194306651, Length=364, Percent_Identity=28.021978021978, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI197927446, Length=361, Percent_Identity=27.7008310249307, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI21361378, Length=361, Percent_Identity=27.7008310249307, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1789272, Length=371, Percent_Identity=40.9703504043127, Blast_Score=253, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17560118, Length=370, Percent_Identity=37.2972972972973, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI71994052, Length=346, Percent_Identity=26.5895953757225, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994045, Length=346, Percent_Identity=26.878612716763, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32563613, Length=340, Percent_Identity=25.5882352941176, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6320222, Length=380, Percent_Identity=33.6842105263158, Blast_Score=176, Evalue=5e-45,
Organism=Drosophila melanogaster, GI20129441, Length=371, Percent_Identity=37.466307277628, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI28571104, Length=338, Percent_Identity=27.810650887574, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI20130091, Length=392, Percent_Identity=24.7448979591837, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 38971; Mature: 38840

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRTPLHDTHVRAGARIVEFAGWQMPVQYSGILAEHETVRTRVGLFDVSHMGEVVFRGP
CCCCCCCCHHHHHCCCEEEEECCCCCCEECCCCHHHHHHHHHHHCEEEHHHHHHHHCCCC
RAIAALGRLFTNDLSKVADGQAQYGCLCRDSGGIVDDVVVYRRSAEDLLVCVNAGNRQKD
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCCC
FEWLAGHAAGADVRNESDDWAQLALQGPLAAQLLQRLTTVNLSAMRSYRFGEGEVAGVRC
HHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEE
IVARTGYTGEDGFELFCRSDLGPRLWDALMEAGVPERIAPCGLGARDSLRLEMAYRLYGS
EEEECCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCEEHEEEEEHHCC
DMDETTTPLEAGLAWVVKLDKGDFIGREALLKQKEQGLSRKLVGFQLTDAGIPRHGYPVL
CCCCCCCHHHCCEEEEEEECCCCCCCHHHHHHHHHHCHHHHHCEEEEECCCCCCCCCCHH
QDGRKVGDVTSGTKSPSLGTAIGLAYVPPALAAEGSTFAVEIRGRAAAAKAVKTPFYTRK
HCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCEEEEEECCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ALRTPLHDTHVRAGARIVEFAGWQMPVQYSGILAEHETVRTRVGLFDVSHMGEVVFRGP
CCCCCCCHHHHHCCCEEEEECCCCCCEECCCCHHHHHHHHHHHCEEEHHHHHHHHCCCC
RAIAALGRLFTNDLSKVADGQAQYGCLCRDSGGIVDDVVVYRRSAEDLLVCVNAGNRQKD
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCCC
FEWLAGHAAGADVRNESDDWAQLALQGPLAAQLLQRLTTVNLSAMRSYRFGEGEVAGVRC
HHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEE
IVARTGYTGEDGFELFCRSDLGPRLWDALMEAGVPERIAPCGLGARDSLRLEMAYRLYGS
EEEECCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCEEHEEEEEHHCC
DMDETTTPLEAGLAWVVKLDKGDFIGREALLKQKEQGLSRKLVGFQLTDAGIPRHGYPVL
CCCCCCCHHHCCEEEEEEECCCCCCCHHHHHHHHHHCHHHHHCEEEEECCCCCCCCCCHH
QDGRKVGDVTSGTKSPSLGTAIGLAYVPPALAAEGSTFAVEIRGRAAAAKAVKTPFYTRK
HCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCEEEEEECCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA