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The map label for this gene is gap1 [H]

Identifier: 220917525

GI number: 220917525

Start: 2683310

End: 2684311

Strand: Reverse

Name: gap1 [H]

Synonym: A2cp1_2425

Alternate gene names: 220917525

Gene position: 2684311-2683310 (Counterclockwise)

Preceding gene: 220917526

Following gene: 220917524

Centisome position: 53.37

GC content: 66.17

Gene sequence:

>1002_bases
ATGGCGCGTATCGCAATCAACGGCTTCGGTCGCATCGGTCGCTGCATCGTTCGCGCTGCCATCGAGCGCGGGGAGAAGGA
CCTGGAGTTCGTCTCCATCAACGACCTCACCGACACGAAGACCCTGGCCCACCTGCTGAAGTACGACTCCGTGCACGGCG
TCCTGAACGCCGACGTGAAGGCCACGGACAAGGGCATCGTGGTGAACGGCAAGGAGATCCAGGTCACGGCCATCAAGTCG
CCGGCCGACCTGCCGCATACCGCGAACAAGGTGGACCTGGTGCTGGAGTGCACCGGCCTGTTCACCGAGCGCGCCAAGGC
CGAGGGCCACCTCCAGGCCGGCGGGCCGCGGGTGCTGATCTCGGCGCCGGCGAAGGGCCCGGACATCACCATCGCCTACG
GCATCAACCACCAGCAGCTCGACCTCGCGAAGCACAAGATCATCTCGAACGCGTCCTGCACCACCAACTGCCTCACGCCG
GTGGCGAAGGTCCTGCTCGAGTCGTTCGGCATCAAGCGCGGCCTGATGACGACGATCCACTCGTACACGAACGACCAGAA
CCTGCTCGACCTGCCGCACAAGGACCTGCGCCGGGCCCGCGCCGCCGCGCTGTCGATGATCCCGTCGACCACCGGCGCCG
CCAAGGCGGTCGCCGAGGTGATCCCGGCGCTGAAGGGCAAGCTGCACGGCACCGCGGTGCGCGTGCCCACGCCGAACGTC
TCCCTGGTGGACCTCACGGTGGAGCTGGAGAAGAGCGCCACCGCCGAGGAGATCAACGCGGAGTTCAAGAAGGCGGCCGA
GGGCGCGCTGAAGGGCGTGCTCGAGTACTCCGAGGCGCCGACCGTCTCGGTGGACTACAACCACAACCCGCACTCGTCGA
TCTTCGACGCCACCAACACCTTCGTCATCGACGGCAACTTCGCGAAGGTGTTCGCCTGGTACGACAACGAGTGGGGCTTC
TCGAACCGCATGGTGGACGTGGCGAAGCTCGTCACGAAGTGA

Upstream 100 bases:

>100_bases
GCTTTTTTTCCGGCTCCATCCCACCTCGTTTCCGTTGACTCCCCATGTCGCGGAAAGTAGCTTAGGCCACCTTTTTCAAC
CCCCAGGAGGAGGGCGGCGC

Downstream 100 bases:

>100_bases
GAGCCGCCATGGCGCTCAGGACCATCGACGCCCTCGAGCTCGCGGGCAAGCGGGTCTTCATCCGCGTGGACTTCAACGTC
CCGCTCGACCCGCAGGGCAG

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MARIAINGFGRIGRCIVRAAIERGEKDLEFVSINDLTDTKTLAHLLKYDSVHGVLNADVKATDKGIVVNGKEIQVTAIKS
PADLPHTANKVDLVLECTGLFTERAKAEGHLQAGGPRVLISAPAKGPDITIAYGINHQQLDLAKHKIISNASCTTNCLTP
VAKVLLESFGIKRGLMTTIHSYTNDQNLLDLPHKDLRRARAAALSMIPSTTGAAKAVAEVIPALKGKLHGTAVRVPTPNV
SLVDLTVELEKSATAEEINAEFKKAAEGALKGVLEYSEAPTVSVDYNHNPHSSIFDATNTFVIDGNFAKVFAWYDNEWGF
SNRMVDVAKLVTK

Sequences:

>Translated_333_residues
MARIAINGFGRIGRCIVRAAIERGEKDLEFVSINDLTDTKTLAHLLKYDSVHGVLNADVKATDKGIVVNGKEIQVTAIKS
PADLPHTANKVDLVLECTGLFTERAKAEGHLQAGGPRVLISAPAKGPDITIAYGINHQQLDLAKHKIISNASCTTNCLTP
VAKVLLESFGIKRGLMTTIHSYTNDQNLLDLPHKDLRRARAAALSMIPSTTGAAKAVAEVIPALKGKLHGTAVRVPTPNV
SLVDLTVELEKSATAEEINAEFKKAAEGALKGVLEYSEAPTVSVDYNHNPHSSIFDATNTFVIDGNFAKVFAWYDNEWGF
SNRMVDVAKLVTK
>Mature_332_residues
ARIAINGFGRIGRCIVRAAIERGEKDLEFVSINDLTDTKTLAHLLKYDSVHGVLNADVKATDKGIVVNGKEIQVTAIKSP
ADLPHTANKVDLVLECTGLFTERAKAEGHLQAGGPRVLISAPAKGPDITIAYGINHQQLDLAKHKIISNASCTTNCLTPV
AKVLLESFGIKRGLMTTIHSYTNDQNLLDLPHKDLRRARAAALSMIPSTTGAAKAVAEVIPALKGKLHGTAVRVPTPNVS
LVDLTVELEKSATAEEINAEFKKAAEGALKGVLEYSEAPTVSVDYNHNPHSSIFDATNTFVIDGNFAKVFAWYDNEWGFS
NRMVDVAKLVTK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=47.0948012232416, Blast_Score=295, Evalue=3e-80,
Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=45.619335347432, Blast_Score=285, Evalue=3e-77,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=49.6987951807229, Blast_Score=320, Evalue=9e-89,
Organism=Escherichia coli, GI1789295, Length=326, Percent_Identity=46.319018404908, Blast_Score=306, Evalue=9e-85,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=46.8468468468468, Blast_Score=300, Evalue=9e-82,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=46.8468468468468, Blast_Score=298, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=45.5357142857143, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=45.5357142857143, Blast_Score=282, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=48.3582089552239, Blast_Score=311, Evalue=7e-86,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=47.7611940298507, Blast_Score=305, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=47.1641791044776, Blast_Score=301, Evalue=1e-82,
Organism=Drosophila melanogaster, GI85725000, Length=334, Percent_Identity=46.4071856287425, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI22023983, Length=334, Percent_Identity=46.4071856287425, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI17933600, Length=334, Percent_Identity=46.1077844311377, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI18110149, Length=334, Percent_Identity=46.1077844311377, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI19922412, Length=329, Percent_Identity=44.6808510638298, Blast_Score=273, Evalue=2e-73,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35869; Mature: 35738

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIAINGFGRIGRCIVRAAIERGEKDLEFVSINDLTDTKTLAHLLKYDSVHGVLNADVK
CCEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCE
ATDKGIVVNGKEIQVTAIKSPADLPHTANKVDLVLECTGLFTERAKAEGHLQAGGPRVLI
ECCCCEEEECCEEEEEEECCCCCCCCCCCCEEEEEEECHHHHHHHCCCCEEECCCCEEEE
SAPAKGPDITIAYGINHQQLDLAKHKIISNASCTTNCLTPVAKVLLESFGIKRGLMTTIH
ECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
SYTNDQNLLDLPHKDLRRARAAALSMIPSTTGAAKAVAEVIPALKGKLHGTAVRVPTPNV
HHCCCCCEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCC
SLVDLTVELEKSATAEEINAEFKKAAEGALKGVLEYSEAPTVSVDYNHNPHSSIFDATNT
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCE
FVIDGNFAKVFAWYDNEWGFSNRMVDVAKLVTK
EEEECCEEEEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
ARIAINGFGRIGRCIVRAAIERGEKDLEFVSINDLTDTKTLAHLLKYDSVHGVLNADVK
CEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCE
ATDKGIVVNGKEIQVTAIKSPADLPHTANKVDLVLECTGLFTERAKAEGHLQAGGPRVLI
ECCCCEEEECCEEEEEEECCCCCCCCCCCCEEEEEEECHHHHHHHCCCCEEECCCCEEEE
SAPAKGPDITIAYGINHQQLDLAKHKIISNASCTTNCLTPVAKVLLESFGIKRGLMTTIH
ECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
SYTNDQNLLDLPHKDLRRARAAALSMIPSTTGAAKAVAEVIPALKGKLHGTAVRVPTPNV
HHCCCCCEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCC
SLVDLTVELEKSATAEEINAEFKKAAEGALKGVLEYSEAPTVSVDYNHNPHSSIFDATNT
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCE
FVIDGNFAKVFAWYDNEWGFSNRMVDVAKLVTK
EEEECCEEEEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA