Click here to switch to the map view.

The map label for this gene is emrK [H]

Identifier: 220917477

GI number: 220917477

Start: 2636194

End: 2637240

Strand: Reverse

Name: emrK [H]

Synonym: A2cp1_2377

Alternate gene names: 220917477

Gene position: 2637240-2636194 (Counterclockwise)

Preceding gene: 220917478

Following gene: 220917476

Centisome position: 52.44

GC content: 77.65

Gene sequence:

>1047_bases
ATGACCCCTCCCGCCGATCCCAGGCTCCACGAGGTCCCGAGCTCCCCCGCGCCGGCGGCCGCCCCGGCGCGTCCGGGCGG
CCGGCGCCGCGTGCTCGTGGGCGCCGTCCTGGCCGCGCTGCTCGTCGCGATCGCGCTCGGCGCGCACGCGCTCCTCACCC
GCGGCGAGGAGAGCACCGACGACGCGCAGGTGGAGGCCGACGTCGTCGCCATCGCGCCGCGGGTGGCCGGCCCGGTGGCC
GAGGTGCTGGTCGCGGACAACGCCCAGGTGCGGCAGGGCCAGCCGCTCGTGCGCGTCGACCCGGCCGACTACGAGGTGCG
CGTCCGCCAGGCCGAGGCCGAGCTGGCGACGGCCCAGGCGCAGGCGGCGGCCGCGGAGGCGCAGGTGTCGGTCGCGCGCG
CCGGGGTGACGCGCGCGGAGGCCGAGTCGGAGAAGGCGGCGCTCGACCTGCGCCGCGCCGAGGAGCTGAAGGCTGGCGAC
GCCATCGCGGCCGAGCGCTACGACGCCACGCGCATCGCCGGCGCCACCGCCCGCGCCGGCGCCGGCGCGAACCGGGCGCA
GTACGCGGCCGCGCTGGCCAGCGGCGAGCTGGCCAGGGCCCGGGTGAAGGCGGCGCAGGCCGCGGTGGACCTGGCGCGCC
TGCAGCGCTCCTACACCGAGGTGCGCGCGCCCGCCTCCGGCCGCGTCTCGCGCCTGGCCGCGCGGGTGGGGCAGATCGTG
CAACCGGGCCAGAGCCTCGGTCAGCTCGTGCCCGACCGGACCTACGTGATCGCGAACTTCAAGGAGACGCAGACCGGCGA
GATCCGCCCCGGCCAGCCGGTGGACGTGGAGATCGACGCGTACGGCGGGCGCACGCTCCACGGCAAGGTGGAGAGCATCT
CCGGCGGGACCGGCGCGCGCTTCGCGCTCCTGCCGCCGGACAACGCGTCCGGGAACTTCGTCAAGGTGGTCGAGCGCGTG
CCGGTGCGGATCGCCTGGGACGCGGTGCCGGCCGATCTTCCCCTGCGCGCCGGCCTCTCCGCGTTCGTGACGGTGCATAC
CAGGTAG

Upstream 100 bases:

>100_bases
CCGGCGTCCTGTTCCTGTGCGTGCTCCCGCTCCTCTACTTCCTCAAGGTGAACCGGCACGGACCGCGCGAGAAGGTCCAC
GTCGAGATGGAGATGTGACC

Downstream 100 bases:

>100_bases
AACGAGGGCTGCGCCCGGCTGCGCCCTCGCCCCGCCGTCGGAGCCGCCGGCGCCCCACACCCGCCCACCCGCGCGGCGTC
CAGACATCGGCCGATTTCTG

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTPPADPRLHEVPSSPAPAAAPARPGGRRRVLVGAVLAALLVAIALGAHALLTRGEESTDDAQVEADVVAIAPRVAGPVA
EVLVADNAQVRQGQPLVRVDPADYEVRVRQAEAELATAQAQAAAAEAQVSVARAGVTRAEAESEKAALDLRRAEELKAGD
AIAAERYDATRIAGATARAGAGANRAQYAAALASGELARARVKAAQAAVDLARLQRSYTEVRAPASGRVSRLAARVGQIV
QPGQSLGQLVPDRTYVIANFKETQTGEIRPGQPVDVEIDAYGGRTLHGKVESISGGTGARFALLPPDNASGNFVKVVERV
PVRIAWDAVPADLPLRAGLSAFVTVHTR

Sequences:

>Translated_348_residues
MTPPADPRLHEVPSSPAPAAAPARPGGRRRVLVGAVLAALLVAIALGAHALLTRGEESTDDAQVEADVVAIAPRVAGPVA
EVLVADNAQVRQGQPLVRVDPADYEVRVRQAEAELATAQAQAAAAEAQVSVARAGVTRAEAESEKAALDLRRAEELKAGD
AIAAERYDATRIAGATARAGAGANRAQYAAALASGELARARVKAAQAAVDLARLQRSYTEVRAPASGRVSRLAARVGQIV
QPGQSLGQLVPDRTYVIANFKETQTGEIRPGQPVDVEIDAYGGRTLHGKVESISGGTGARFALLPPDNASGNFVKVVERV
PVRIAWDAVPADLPLRAGLSAFVTVHTR
>Mature_347_residues
TPPADPRLHEVPSSPAPAAAPARPGGRRRVLVGAVLAALLVAIALGAHALLTRGEESTDDAQVEADVVAIAPRVAGPVAE
VLVADNAQVRQGQPLVRVDPADYEVRVRQAEAELATAQAQAAAAEAQVSVARAGVTRAEAESEKAALDLRRAEELKAGDA
IAAERYDATRIAGATARAGAGANRAQYAAALASGELARARVKAAQAAVDLARLQRSYTEVRAPASGRVSRLAARVGQIVQ
PGQSLGQLVPDRTYVIANFKETQTGEIRPGQPVDVEIDAYGGRTLHGKVESISGGTGARFALLPPDNASGNFVKVVERVP
VRIAWDAVPADLPLRAGLSAFVTVHTR

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=337, Percent_Identity=34.4213649851632, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789041, Length=351, Percent_Identity=35.042735042735, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1790519, Length=300, Percent_Identity=36.3333333333333, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87081951, Length=319, Percent_Identity=28.8401253918495, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790024, Length=265, Percent_Identity=26.7924528301887, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790012, Length=262, Percent_Identity=26.3358778625954, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 36101; Mature: 35970

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPADPRLHEVPSSPAPAAAPARPGGRRRVLVGAVLAALLVAIALGAHALLTRGEESTD
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DAQVEADVVAIAPRVAGPVAEVLVADNAQVRQGQPLVRVDPADYEVRVRQAEAELATAQA
CCCEEEEEEEECCHHCCHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHH
QAAAAEAQVSVARAGVTRAEAESEKAALDLRRAEELKAGDAIAAERYDATRIAGATARAG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHCCCCCCCC
AGANRAQYAAALASGELARARVKAAQAAVDLARLQRSYTEVRAPASGRVSRLAARVGQIV
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QPGQSLGQLVPDRTYVIANFKETQTGEIRPGQPVDVEIDAYGGRTLHGKVESISGGTGAR
CCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEECEEEECCCCCCCE
FALLPPDNASGNFVKVVERVPVRIAWDAVPADLPLRAGLSAFVTVHTR
EEEECCCCCCCCHHHHHHHCCEEEEECCCCCCCCHHCCCEEEEEEECC
>Mature Secondary Structure 
TPPADPRLHEVPSSPAPAAAPARPGGRRRVLVGAVLAALLVAIALGAHALLTRGEESTD
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DAQVEADVVAIAPRVAGPVAEVLVADNAQVRQGQPLVRVDPADYEVRVRQAEAELATAQA
CCCEEEEEEEECCHHCCHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHH
QAAAAEAQVSVARAGVTRAEAESEKAALDLRRAEELKAGDAIAAERYDATRIAGATARAG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHCCCCCCCC
AGANRAQYAAALASGELARARVKAAQAAVDLARLQRSYTEVRAPASGRVSRLAARVGQIV
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QPGQSLGQLVPDRTYVIANFKETQTGEIRPGQPVDVEIDAYGGRTLHGKVESISGGTGAR
CCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEECEEEECCCCCCCE
FALLPPDNASGNFVKVVERVPVRIAWDAVPADLPLRAGLSAFVTVHTR
EEEECCCCCCCCHHHHHHHCCEEEEECCCCCCCCHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]