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The map label for this gene is atoS [H]

Identifier: 220916851

GI number: 220916851

Start: 1950988

End: 1953540

Strand: Direct

Name: atoS [H]

Synonym: A2cp1_1747

Alternate gene names: 220916851

Gene position: 1950988-1953540 (Clockwise)

Preceding gene: 220916850

Following gene: 220916853

Centisome position: 38.79

GC content: 75.79

Gene sequence:

>2553_bases
GTGAGCGGCGAAGAACAGCGGACCCCGGTCCCGGCCTGGGCGTCGTCGCGGGCGGCCCCGGCGCTGGTGGTGGCGGTCGC
GATCATCGACCTGCTGGCCGTCCTGCTGGTCGGGTCCTCGGTCGAGCAGAGCCGGCTCCACCAGCACGAGCGCGCCACCG
CGGCCACCCAGAACCTGGCCGCCGCGCTGGAGCAGTACCTCGGCGGCATCTTCGAGAAGGTCGAGCTGACGCTGCTCACG
GTGGCCGACGAGTATGCGCGCGAGTCGGCCGCGGGCCGGCTGGACGCGCCGGTGTTCGACGACTTCCTGGCGCGCCAGCG
CGGACGCATCCCGCAGGTCCACGCGCTCGAGGTCTTCGACGCGAACGGGGTGCTGGCGCACGGCCGCGACGCGCCCCCCG
GGGTCATCAGCGACATCTCCGACCGCGAGTACTTCCGGCGGCTGCGGGACGACCCCGGCCTCGGCGTGCTCGTCTCGAGC
CCGCTCGTGGGACGGCTCACCGCCCGCCCGCAGCTGGTCATGGCCCGCGCGCTCCGGCGCGCGGACGGCGGCTTCGCCGG
CGTCGCGGTCGCGAGCGTGCTGCTGGAGGACCTGGCCCACGCGCTGGAGGGCTACGACGTGGGCGCGCGGGGCGTCATCG
TGCTGCGCGATCCCGACCTGGGCGTGGTGGTGCGCCGCCAGAGCTCCGGCGCGCCCATCGCGCTCGGCGACCGCACCGTC
TCGCCCGAGCTGCTGGCGCTGCTCCGCGACGGCCACCGCGCCGCCACCTACTCCGGCGTGGCGGTGGACGGCGTCGAGCG
CACCTTCACGTTCCGGCGGATGGCGCGCACCGGGCACCTCGTCATCGTGGGGCTCGCGTGCGACGACTACCTCGCCGGCT
GGCGCCGCTCCACGCTGCTCGCCACCGCCGTGCTCGCCGCCTTCGGCCTGCTCACCGCCGCCGCGGCCTGGCTGACGCTG
CGCGCCTGGCGCCGGCACCAGGCGGCGGTGCAGGACCTCGCCGAGCAGGAGACCCGCTTCCGCCTGCTGGCCGAGAGCGC
CACCGACGTGATCTGGATGGTGGACGCGGCGCGCCGCCTCACCTACGTGAGCCCGGCGGTGCAGCGCCTGGCAGGGTGGA
CGCCGGAGGAGGCGTGCCGCGTCCGCTGGCCGCGGCTCCTGTCGCGGCCGTCCATCGAGCGGATCCGCTCGGCGCTCGCC
CGGCTCGGCGCGGTGGCGCCGCACGCGCAGCCGTTCGCCGATGCGCTCATCGAGCACGAGGTGGTGGCCAAGGACGGCCG
GCGGGTCCACGCGGAGTCGCGCTTCAGCCTCCTGTGGAGCGCCGACGGGCAGGTGCTCGGCGCCATCGGCGTGACCCGCG
ACGTCACCGAGCGGCGGGAGATGCAGGCGCGGGTCCAGGTCGCGGAGCGCATGGCGTCGCTCGGGACGATGGCGGCCGGC
GTCGCCCACGAGGTGAACAACCCGCTCACCTACGTGTACGGCAACGTGGCGTTCGCGCTGGAGCGGCTGCGGTCGGTGGA
CGTCGCGCGCGGCCGGCAGGGGCCGGTCGACGAGGCGCTCCAGGCGCTGCGCGAGGCGCTGGCCGGCGCCGACCGCGTCC
GCCACATCGTGCGCGACCTGAAGGCGTTCTCGCGCGCCGAGGACGGCCGGCTCGAGCCGGTGGACGTGGGGCAGGTCATC
GAGGGCTGCCTCAAGATGACCGCGACGCTCACCGGCGACCGGGCGCAGGTGAGCGTGCGGCTCGGGCCGGTCCCGCGGGT
CCTGGCGAGCGAGGCGCGGATCGGGCAGGTGATGCTGAACCTGATCGTGAACGCCGCGCACGCCATCCCCGAGGGCGACC
CCGACGCGAACCGCATCGAGGTCTCCACCGCGCTCGCCGCGGACGGGCGCGTCGAGGTGGTGGTGACCGACACCGGCACG
GGCATCGCGCCCGAGGTGCTGCCCCGCATCTTCGACCCGTTCTTCACCACCAAGGGCGTGGGGGAGGGGACGGGGCTGGG
CCTGTCGATCTGCCACGGGATCGTGAAGGGGCTGGACGGCGAGATCGACGTCGAGACGGCGGTGGGACGGGGGAGCCGGT
TCCGCGTGCTGCTCCCGCCGGCGCCGGAAGGCGCCGTGGCCGCGCCGGCGGAGGCGCCCATCGCGCCCGCCGCGCCGCCC
CGGCGGCGGGTGCTGGTGCTCGACGACGATCCGCTGGTGGCGCGCGCCATCGGCCGGACGCTCTCGCGCGACTGCGCGGT
GGACGTGAGCACCGACCCGGTGCAGGCCCTCCGGCGCGTCCACTCGGGCGAGCGCTGGGACGTGATCCTCTGCGACCTGA
TGATGCCCGAGCTCGCCGGGATGGACGTCCACGCGTCCATCCAGGAGATCGATCCCGGCCAGGCGGCGCGCATCGTGTTC
ATGACCGGCGGCGCGTTCACCACCCGGGCGCGCGAGTTCCTGGAGCGCGTCCCGAACGCCCGGCTCGAGAAGCCCCTCGA
CCCGGCCACGCTGGCGCGGGTGCTCGAGGCGGGCGGCCGCGGAGCGCCGGGCGACGGGACGGCCGGACGCTGA

Upstream 100 bases:

>100_bases
GCGCGCCGGCGCAGGTCGGCGCTTCCGACGCCGGCGCCCGGAGGGTACTCTCGCTGCTCGACCGGGGGCGCGTGGCCCCC
GGCGCCCCCGGAGCGCGAGC

Downstream 100 bases:

>100_bases
GGCTCAGGCCGGGCGCAGTCGCCCGAGCAGCACCGGCGCGCACGGGGGCGGCGGGGCCCGCTGGTCCCGGCGCTCCGACT
CCCGCTCCGCCAGCACGGCC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 850; Mature: 849

Protein sequence:

>850_residues
MSGEEQRTPVPAWASSRAAPALVVAVAIIDLLAVLLVGSSVEQSRLHQHERATAATQNLAAALEQYLGGIFEKVELTLLT
VADEYARESAAGRLDAPVFDDFLARQRGRIPQVHALEVFDANGVLAHGRDAPPGVISDISDREYFRRLRDDPGLGVLVSS
PLVGRLTARPQLVMARALRRADGGFAGVAVASVLLEDLAHALEGYDVGARGVIVLRDPDLGVVVRRQSSGAPIALGDRTV
SPELLALLRDGHRAATYSGVAVDGVERTFTFRRMARTGHLVIVGLACDDYLAGWRRSTLLATAVLAAFGLLTAAAAWLTL
RAWRRHQAAVQDLAEQETRFRLLAESATDVIWMVDAARRLTYVSPAVQRLAGWTPEEACRVRWPRLLSRPSIERIRSALA
RLGAVAPHAQPFADALIEHEVVAKDGRRVHAESRFSLLWSADGQVLGAIGVTRDVTERREMQARVQVAERMASLGTMAAG
VAHEVNNPLTYVYGNVAFALERLRSVDVARGRQGPVDEALQALREALAGADRVRHIVRDLKAFSRAEDGRLEPVDVGQVI
EGCLKMTATLTGDRAQVSVRLGPVPRVLASEARIGQVMLNLIVNAAHAIPEGDPDANRIEVSTALAADGRVEVVVTDTGT
GIAPEVLPRIFDPFFTTKGVGEGTGLGLSICHGIVKGLDGEIDVETAVGRGSRFRVLLPPAPEGAVAAPAEAPIAPAAPP
RRRVLVLDDDPLVARAIGRTLSRDCAVDVSTDPVQALRRVHSGERWDVILCDLMMPELAGMDVHASIQEIDPGQAARIVF
MTGGAFTTRAREFLERVPNARLEKPLDPATLARVLEAGGRGAPGDGTAGR

Sequences:

>Translated_850_residues
MSGEEQRTPVPAWASSRAAPALVVAVAIIDLLAVLLVGSSVEQSRLHQHERATAATQNLAAALEQYLGGIFEKVELTLLT
VADEYARESAAGRLDAPVFDDFLARQRGRIPQVHALEVFDANGVLAHGRDAPPGVISDISDREYFRRLRDDPGLGVLVSS
PLVGRLTARPQLVMARALRRADGGFAGVAVASVLLEDLAHALEGYDVGARGVIVLRDPDLGVVVRRQSSGAPIALGDRTV
SPELLALLRDGHRAATYSGVAVDGVERTFTFRRMARTGHLVIVGLACDDYLAGWRRSTLLATAVLAAFGLLTAAAAWLTL
RAWRRHQAAVQDLAEQETRFRLLAESATDVIWMVDAARRLTYVSPAVQRLAGWTPEEACRVRWPRLLSRPSIERIRSALA
RLGAVAPHAQPFADALIEHEVVAKDGRRVHAESRFSLLWSADGQVLGAIGVTRDVTERREMQARVQVAERMASLGTMAAG
VAHEVNNPLTYVYGNVAFALERLRSVDVARGRQGPVDEALQALREALAGADRVRHIVRDLKAFSRAEDGRLEPVDVGQVI
EGCLKMTATLTGDRAQVSVRLGPVPRVLASEARIGQVMLNLIVNAAHAIPEGDPDANRIEVSTALAADGRVEVVVTDTGT
GIAPEVLPRIFDPFFTTKGVGEGTGLGLSICHGIVKGLDGEIDVETAVGRGSRFRVLLPPAPEGAVAAPAEAPIAPAAPP
RRRVLVLDDDPLVARAIGRTLSRDCAVDVSTDPVQALRRVHSGERWDVILCDLMMPELAGMDVHASIQEIDPGQAARIVF
MTGGAFTTRAREFLERVPNARLEKPLDPATLARVLEAGGRGAPGDGTAGR
>Mature_849_residues
SGEEQRTPVPAWASSRAAPALVVAVAIIDLLAVLLVGSSVEQSRLHQHERATAATQNLAAALEQYLGGIFEKVELTLLTV
ADEYARESAAGRLDAPVFDDFLARQRGRIPQVHALEVFDANGVLAHGRDAPPGVISDISDREYFRRLRDDPGLGVLVSSP
LVGRLTARPQLVMARALRRADGGFAGVAVASVLLEDLAHALEGYDVGARGVIVLRDPDLGVVVRRQSSGAPIALGDRTVS
PELLALLRDGHRAATYSGVAVDGVERTFTFRRMARTGHLVIVGLACDDYLAGWRRSTLLATAVLAAFGLLTAAAAWLTLR
AWRRHQAAVQDLAEQETRFRLLAESATDVIWMVDAARRLTYVSPAVQRLAGWTPEEACRVRWPRLLSRPSIERIRSALAR
LGAVAPHAQPFADALIEHEVVAKDGRRVHAESRFSLLWSADGQVLGAIGVTRDVTERREMQARVQVAERMASLGTMAAGV
AHEVNNPLTYVYGNVAFALERLRSVDVARGRQGPVDEALQALREALAGADRVRHIVRDLKAFSRAEDGRLEPVDVGQVIE
GCLKMTATLTGDRAQVSVRLGPVPRVLASEARIGQVMLNLIVNAAHAIPEGDPDANRIEVSTALAADGRVEVVVTDTGTG
IAPEVLPRIFDPFFTTKGVGEGTGLGLSICHGIVKGLDGEIDVETAVGRGSRFRVLLPPAPEGAVAAPAEAPIAPAAPPR
RRVLVLDDDPLVARAIGRTLSRDCAVDVSTDPVQALRRVHSGERWDVILCDLMMPELAGMDVHASIQEIDPGQAARIVFM
TGGAFTTRAREFLERVPNARLEKPLDPATLARVLEAGGRGAPGDGTAGR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=385, Percent_Identity=29.8701298701299, Blast_Score=139, Evalue=9e-34,
Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=33.2046332046332, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788713, Length=419, Percent_Identity=24.582338902148, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI48994928, Length=535, Percent_Identity=22.803738317757, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI145693157, Length=275, Percent_Identity=30.5454545454545, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786600, Length=259, Percent_Identity=28.1853281853282, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=29.0598290598291, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=370, Percent_Identity=26.2162162162162, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=346, Percent_Identity=26.0115606936416, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91075; Mature: 90944

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEEQRTPVPAWASSRAAPALVVAVAIIDLLAVLLVGSSVEQSRLHQHERATAATQNLA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AALEQYLGGIFEKVELTLLTVADEYARESAAGRLDAPVFDDFLARQRGRIPQVHALEVFD
HHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEC
ANGVLAHGRDAPPGVISDISDREYFRRLRDDPGLGVLVSSPLVGRLTARPQLVMARALRR
CCCCEECCCCCCCCHHHCCCHHHHHHHHCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHH
ADGGFAGVAVASVLLEDLAHALEGYDVGARGVIVLRDPDLGVVVRRQSSGAPIALGDRTV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEECCCCCCEEECCCCC
SPELLALLRDGHRAATYSGVAVDGVERTFTFRRMARTGHLVIVGLACDDYLAGWRRSTLL
CHHHHHHHHCCCCCEEECCEEECCHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHH
ATAVLAAFGLLTAAAAWLTLRAWRRHQAAVQDLAEQETRFRLLAESATDVIWMVDAARRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
TYVSPAVQRLAGWTPEEACRVRWPRLLSRPSIERIRSALARLGAVAPHAQPFADALIEHE
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VVAKDGRRVHAESRFSLLWSADGQVLGAIGVTRDVTERREMQARVQVAERMASLGTMAAG
HHHCCCCEEECCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAHEVNNPLTYVYGNVAFALERLRSVDVARGRQGPVDEALQALREALAGADRVRHIVRDL
HHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KAFSRAEDGRLEPVDVGQVIEGCLKMTATLTGDRAQVSVRLGPVPRVLASEARIGQVMLN
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LIVNAAHAIPEGDPDANRIEVSTALAADGRVEVVVTDTGTGIAPEVLPRIFDPFFTTKGV
HHHHHHHHCCCCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCC
GEGTGLGLSICHGIVKGLDGEIDVETAVGRGSRFRVLLPPAPEGAVAAPAEAPIAPAAPP
CCCCCCHHHHHHHHHHCCCCCEEEEHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
RRRVLVLDDDPLVARAIGRTLSRDCAVDVSTDPVQALRRVHSGERWDVILCDLMMPELAG
CCEEEEECCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHCC
MDVHASIQEIDPGQAARIVFMTGGAFTTRAREFLERVPNARLEKPLDPATLARVLEAGGR
CCCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
GAPGDGTAGR
CCCCCCCCCC
>Mature Secondary Structure 
SGEEQRTPVPAWASSRAAPALVVAVAIIDLLAVLLVGSSVEQSRLHQHERATAATQNLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AALEQYLGGIFEKVELTLLTVADEYARESAAGRLDAPVFDDFLARQRGRIPQVHALEVFD
HHHHHHHHHHHHHHHHHEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEC
ANGVLAHGRDAPPGVISDISDREYFRRLRDDPGLGVLVSSPLVGRLTARPQLVMARALRR
CCCCEECCCCCCCCHHHCCCHHHHHHHHCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHH
ADGGFAGVAVASVLLEDLAHALEGYDVGARGVIVLRDPDLGVVVRRQSSGAPIALGDRTV
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEECCCCCCEEECCCCC
SPELLALLRDGHRAATYSGVAVDGVERTFTFRRMARTGHLVIVGLACDDYLAGWRRSTLL
CHHHHHHHHCCCCCEEECCEEECCHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHH
ATAVLAAFGLLTAAAAWLTLRAWRRHQAAVQDLAEQETRFRLLAESATDVIWMVDAARRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHH
TYVSPAVQRLAGWTPEEACRVRWPRLLSRPSIERIRSALARLGAVAPHAQPFADALIEHE
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VVAKDGRRVHAESRFSLLWSADGQVLGAIGVTRDVTERREMQARVQVAERMASLGTMAAG
HHHCCCCEEECCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAHEVNNPLTYVYGNVAFALERLRSVDVARGRQGPVDEALQALREALAGADRVRHIVRDL
HHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KAFSRAEDGRLEPVDVGQVIEGCLKMTATLTGDRAQVSVRLGPVPRVLASEARIGQVMLN
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHH
LIVNAAHAIPEGDPDANRIEVSTALAADGRVEVVVTDTGTGIAPEVLPRIFDPFFTTKGV
HHHHHHHHCCCCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCC
GEGTGLGLSICHGIVKGLDGEIDVETAVGRGSRFRVLLPPAPEGAVAAPAEAPIAPAAPP
CCCCCCHHHHHHHHHHCCCCCEEEEHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCC
RRRVLVLDDDPLVARAIGRTLSRDCAVDVSTDPVQALRRVHSGERWDVILCDLMMPELAG
CCEEEEECCCCHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHCC
MDVHASIQEIDPGQAARIVFMTGGAFTTRAREFLERVPNARLEKPLDPATLARVLEAGGR
CCCCCHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
GAPGDGTAGR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]