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The map label for this gene is yafC [C]

Identifier: 220916849

GI number: 220916849

Start: 1949435

End: 1950442

Strand: Direct

Name: yafC [C]

Synonym: A2cp1_1745

Alternate gene names: 220916849

Gene position: 1949435-1950442 (Clockwise)

Preceding gene: 220916848

Following gene: 220916850

Centisome position: 38.76

GC content: 80.85

Gene sequence:

>1008_bases
ATGATCGCGGCTGACGCGAGCCTGGACGACCTCCGGCTGCTCGTGGAGGTGGTGGCGACCGGCGGCCTCACGGCGGCGGC
GGCGCGCCTCGGCCTGCGCAAGTCCACCGTGAGCCGCCGGCTCGCCGCGCTCGAGGAGCGCCTCGGCGTCCGGCTCCTGG
AGCGGAACGCGCGCCGGCTGCGGCTCACCGAGGCGGGCCGCGCGTACCACGCCCGCGCCGCGCGGCTCGTGGCCGAGGCC
CGCGCGCTCGACCGGGAGACCGCCGAGGCCCGCGGCGCGCCGCAGGGCACGCTGCGGATCGCGACGCCGGCCCTGCTCGG
CGAGCTGCTCGCGCCCGCGGTGGCCGAGCTGCTGCTCCGCCACCCGCGCCTGGGGGTCGAGCTCGCGCTCGCGCCGCCGC
ACGTGGACCTGCTCGCGGAGGAGCACGACCTGGCGCTGCGCACCGGCCCGCTCGCCGACTCCTCCCTGGTGGCGCGCCGC
CTCGGGACCCTGCGCACCGGCTGCTACGCGAGCCCCGCCTACCTGGCTCGCCGCGGCACGCCGGCCACGCCGGACGCGCT
GCGCGACGAGGCGGAGGCGCACGATTGCATCCTGCTCGCCGAGGCCGGCACCGACGAGATCTGGTTCTTCGGCGCGGGCG
CCACGGCGCGGACGGTGCGCCCCGCCGGCCGCCTGCGCGTGCCCAGCGTGCACGCCGGGCAGCTCGCCGCCCGCGCCGGG
CTCGGCGTGGTGCGCCTGCCGGCGGCGCTCGTCGCGGACGACGTGCGGTCCGGGCGGCTCGTGGCGGTGCTCGAGGCGGA
GACGCCGCCGGGCATGCCGGTCCACGCGGTCTACCCGAGCGGCCGGCACCTCGCGCCCAAGGTGCGCGCCTTCCTCGAGC
TGGTGTCGGGCGGCGCCGCGGCGCTGCCGTGGGATCCGCCGGGGCGCGCGCCGGCCGTGGGGCCGGGGGACGCCGCGGAA
CGCAGCGTTCCGGCGCGGCCGGTCGCCCCGGCGCGCCGCCGCGGGTAG

Upstream 100 bases:

>100_bases
CGCCGCGCGCCGCGCGGCGTCCCCGATTCCGGCCCGGGGCTCCGCGCCGGGCGCGGTCGCGCCGGCCGCCGCCGAGCGGG
CGGGGTGACGCCCTCGCGCC

Downstream 100 bases:

>100_bases
ATCCGGTCCGCGCGGCGGCCGGGCACTCCGCCCGGCGGCGCGGGCGGAGGCGGCCATGGCGAGCGGCGTGATGGACATCG
GGGACGCGGAGTTCGAGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MIAADASLDDLRLLVEVVATGGLTAAAARLGLRKSTVSRRLAALEERLGVRLLERNARRLRLTEAGRAYHARAARLVAEA
RALDRETAEARGAPQGTLRIATPALLGELLAPAVAELLLRHPRLGVELALAPPHVDLLAEEHDLALRTGPLADSSLVARR
LGTLRTGCYASPAYLARRGTPATPDALRDEAEAHDCILLAEAGTDEIWFFGAGATARTVRPAGRLRVPSVHAGQLAARAG
LGVVRLPAALVADDVRSGRLVAVLEAETPPGMPVHAVYPSGRHLAPKVRAFLELVSGGAAALPWDPPGRAPAVGPGDAAE
RSVPARPVAPARRRG

Sequences:

>Translated_335_residues
MIAADASLDDLRLLVEVVATGGLTAAAARLGLRKSTVSRRLAALEERLGVRLLERNARRLRLTEAGRAYHARAARLVAEA
RALDRETAEARGAPQGTLRIATPALLGELLAPAVAELLLRHPRLGVELALAPPHVDLLAEEHDLALRTGPLADSSLVARR
LGTLRTGCYASPAYLARRGTPATPDALRDEAEAHDCILLAEAGTDEIWFFGAGATARTVRPAGRLRVPSVHAGQLAARAG
LGVVRLPAALVADDVRSGRLVAVLEAETPPGMPVHAVYPSGRHLAPKVRAFLELVSGGAAALPWDPPGRAPAVGPGDAAE
RSVPARPVAPARRRG
>Mature_335_residues
MIAADASLDDLRLLVEVVATGGLTAAAARLGLRKSTVSRRLAALEERLGVRLLERNARRLRLTEAGRAYHARAARLVAEA
RALDRETAEARGAPQGTLRIATPALLGELLAPAVAELLLRHPRLGVELALAPPHVDLLAEEHDLALRTGPLADSSLVARR
LGTLRTGCYASPAYLARRGTPATPDALRDEAEAHDCILLAEAGTDEIWFFGAGATARTVRPAGRLRVPSVHAGQLAARAG
LGVVRLPAALVADDVRSGRLVAVLEAETPPGMPVHAVYPSGRHLAPKVRAFLELVSGGAAALPWDPPGRAPAVGPGDAAE
RSVPARPVAPARRRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=308, Percent_Identity=32.4675324675325, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=32.5259515570934, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=29.616724738676, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=29.4915254237288, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787589, Length=286, Percent_Identity=29.020979020979, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787128, Length=301, Percent_Identity=28.2392026578073, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=31.2925170068027, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790011, Length=297, Percent_Identity=23.9057239057239, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788481, Length=292, Percent_Identity=26.7123287671233, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=31.9327731092437, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35108; Mature: 35108

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAADASLDDLRLLVEVVATGGLTAAAARLGLRKSTVSRRLAALEERLGVRLLERNARRL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RLTEAGRAYHARAARLVAEARALDRETAEARGAPQGTLRIATPALLGELLAPAVAELLLR
EEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
HPRLGVELALAPPHVDLLAEEHDLALRTGPLADSSLVARRLGTLRTGCYASPAYLARRGT
CCCCCEEEEECCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCC
PATPDALRDEAEAHDCILLAEAGTDEIWFFGAGATARTVRPAGRLRVPSVHAGQLAARAG
CCCHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCEECCCCCEECCCCCHHHHHHHHC
LGVVRLPAALVADDVRSGRLVAVLEAETPPGMPVHAVYPSGRHLAPKVRAFLELVSGGAA
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCE
ALPWDPPGRAPAVGPGDAAERSVPARPVAPARRRG
ECCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHCCC
>Mature Secondary Structure
MIAADASLDDLRLLVEVVATGGLTAAAARLGLRKSTVSRRLAALEERLGVRLLERNARRL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
RLTEAGRAYHARAARLVAEARALDRETAEARGAPQGTLRIATPALLGELLAPAVAELLLR
EEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
HPRLGVELALAPPHVDLLAEEHDLALRTGPLADSSLVARRLGTLRTGCYASPAYLARRGT
CCCCCEEEEECCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCC
PATPDALRDEAEAHDCILLAEAGTDEIWFFGAGATARTVRPAGRLRVPSVHAGQLAARAG
CCCHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCEECCCCCEECCCCCHHHHHHHHC
LGVVRLPAALVADDVRSGRLVAVLEAETPPGMPVHAVYPSGRHLAPKVRAFLELVSGGAA
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCE
ALPWDPPGRAPAVGPGDAAERSVPARPVAPARRRG
ECCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]