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The map label for this gene is ctaC [H]

Identifier: 220916781

GI number: 220916781

Start: 1867546

End: 1868559

Strand: Direct

Name: ctaC [H]

Synonym: A2cp1_1676

Alternate gene names: 220916781

Gene position: 1867546-1868559 (Clockwise)

Preceding gene: 220916780

Following gene: 220916782

Centisome position: 37.13

GC content: 72.09

Gene sequence:

>1014_bases
GTGACCGAGCTGCCCATCCGCACCCTCCACCTCCTCGCCGGGGCAGGCCCCGGCTACCTCCCCGCGCGCGCGTCCAGCGT
GGCGGACGGGGTGGACCAGGTCTTCCTGTTCCTCTTCTGGGTGAGCGCCTTCTTCCTCGCGCTCATCATCCTCCTCACCA
TCGTCTTCGTGCTGCGGTACCGCCGCCGCCCGGCGCGGCTGCACCCGGAGCCCTCGCCGGCGCACAGCACGCGGCTCGAG
CTGGTGTGGACCATCATCCCGCTGGCGCTCGTCATGGCGCTGTTCGTCATGTCCACCCGCACCTGGATCCAGATGACCTC
GGCGGACCCCGGGGCGGATCCGGTGCGCGTGCAGGTGACCGGGCGCAAGTGGTCGTGGTGGTTCGACCACCCGGGTGGCA
AGGGCGCGAACGAGCTGCACGTGGTGGCCGGGCGGCCGGTGGAGCTGGTCCTCTCCGCCACCGACGTGATCCACTCGCTG
TACGTCCCGGAGTTCCGCCTGAAGCAGGACGCGGTCCCCGGGCGTTTCACCCGGCTCGCCTTCACGCCCACCGTGCCGGG
CAGCTACCCCATCCTCTGCGCCGAGTACTGCGGCACCGACCACTCCCGCATGCTGTCCACCGTGGTGGTCCACGCCGACC
AGGCCTCGTTCGACGCCTGGGCCAGGGAGGGCCTCCCGGCCGACGCCACGCTCGCCGACCTCGGCAAGCAGGTGTTCGCG
GAGAAGGGCTGCGCCGCCTGCCACAGCGTGGACGGGGCGCGGGGCGTCGGCCCGTCGGTCCGCGGGCTGTGGAAGCGCCA
CGAGAAGCTGGCGGACGGCACCACCGCGCTGGTGGACGAGGAGTACCTGCGCGAGTCGCTGGTGAAGCCGGGCGCGAAGG
TGGTCGCCGGATACCCGAACATCATGCCGCCCATGCCGCTGGAGGAGCGCGAGCTGAAGGCCGTCGCCGCGTACCTCGAG
ACGCTCGCCGTCGAGGGCGGCGCGCCGGCGAAGGGCGAGGAGACGAAGCGATGA

Upstream 100 bases:

>100_bases
AGGTGATGCGCGCGGCGGGCGGGGTGGTCGGGCTCTTCCTCGTCTCCTTCGTCGGCGTCCACGTCGCGCGCGATCGTCGG
CGCCGAATCAGGAACGCACC

Downstream 100 bases:

>100_bases
GCAGCACCGCGGCAGTGGCCGTGCGCGCGCCGGCGCACGAGACCGGGAGCTACCTCGAGCACGGGCGCGGCGTCCGCTCC
TGGCTCTTCACCCTGGACCA

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTELPIRTLHLLAGAGPGYLPARASSVADGVDQVFLFLFWVSAFFLALIILLTIVFVLRYRRRPARLHPEPSPAHSTRLE
LVWTIIPLALVMALFVMSTRTWIQMTSADPGADPVRVQVTGRKWSWWFDHPGGKGANELHVVAGRPVELVLSATDVIHSL
YVPEFRLKQDAVPGRFTRLAFTPTVPGSYPILCAEYCGTDHSRMLSTVVVHADQASFDAWAREGLPADATLADLGKQVFA
EKGCAACHSVDGARGVGPSVRGLWKRHEKLADGTTALVDEEYLRESLVKPGAKVVAGYPNIMPPMPLEERELKAVAAYLE
TLAVEGGAPAKGEETKR

Sequences:

>Translated_337_residues
MTELPIRTLHLLAGAGPGYLPARASSVADGVDQVFLFLFWVSAFFLALIILLTIVFVLRYRRRPARLHPEPSPAHSTRLE
LVWTIIPLALVMALFVMSTRTWIQMTSADPGADPVRVQVTGRKWSWWFDHPGGKGANELHVVAGRPVELVLSATDVIHSL
YVPEFRLKQDAVPGRFTRLAFTPTVPGSYPILCAEYCGTDHSRMLSTVVVHADQASFDAWAREGLPADATLADLGKQVFA
EKGCAACHSVDGARGVGPSVRGLWKRHEKLADGTTALVDEEYLRESLVKPGAKVVAGYPNIMPPMPLEERELKAVAAYLE
TLAVEGGAPAKGEETKR
>Mature_336_residues
TELPIRTLHLLAGAGPGYLPARASSVADGVDQVFLFLFWVSAFFLALIILLTIVFVLRYRRRPARLHPEPSPAHSTRLEL
VWTIIPLALVMALFVMSTRTWIQMTSADPGADPVRVQVTGRKWSWWFDHPGGKGANELHVVAGRPVELVLSATDVIHSLY
VPEFRLKQDAVPGRFTRLAFTPTVPGSYPILCAEYCGTDHSRMLSTVVVHADQASFDAWAREGLPADATLADLGKQVFAE
KGCAACHSVDGARGVGPSVRGLWKRHEKLADGTTALVDEEYLRESLVKPGAKVVAGYPNIMPPMPLEERELKAVAAYLET
LAVEGGAPAKGEETKR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=184, Percent_Identity=29.3478260869565, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1786635, Length=236, Percent_Identity=27.9661016949153, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 36825; Mature: 36694

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPIRTLHLLAGAGPGYLPARASSVADGVDQVFLFLFWVSAFFLALIILLTIVFVLRY
CCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRPARLHPEPSPAHSTRLELVWTIIPLALVMALFVMSTRTWIQMTSADPGADPVRVQVT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEE
GRKWSWWFDHPGGKGANELHVVAGRPVELVLSATDVIHSLYVPEFRLKQDAVPGRFTRLA
CCEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEE
FTPTVPGSYPILCAEYCGTDHSRMLSTVVVHADQASFDAWAREGLPADATLADLGKQVFA
ECCCCCCCCCEEEHHHCCCCHHHHHHHHHEECCCHHHHHHHHCCCCCCHHHHHHHHHHHH
EKGCAACHSVDGARGVGPSVRGLWKRHEKLADGTTALVDEEYLRESLVKPGAKVVAGYPN
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCC
IMPPMPLEERELKAVAAYLETLAVEGGAPAKGEETKR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TELPIRTLHLLAGAGPGYLPARASSVADGVDQVFLFLFWVSAFFLALIILLTIVFVLRY
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRPARLHPEPSPAHSTRLELVWTIIPLALVMALFVMSTRTWIQMTSADPGADPVRVQVT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEE
GRKWSWWFDHPGGKGANELHVVAGRPVELVLSATDVIHSLYVPEFRLKQDAVPGRFTRLA
CCEEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEE
FTPTVPGSYPILCAEYCGTDHSRMLSTVVVHADQASFDAWAREGLPADATLADLGKQVFA
ECCCCCCCCCEEEHHHCCCCHHHHHHHHHEECCCHHHHHHHHCCCCCCHHHHHHHHHHHH
EKGCAACHSVDGARGVGPSVRGLWKRHEKLADGTTALVDEEYLRESLVKPGAKVVAGYPN
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCC
IMPPMPLEERELKAVAAYLETLAVEGGAPAKGEETKR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383492; 8387368; 8905231 [H]