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The map label for this gene is rnz [H]

Identifier: 220916746

GI number: 220916746

Start: 1831509

End: 1832477

Strand: Direct

Name: rnz [H]

Synonym: A2cp1_1641

Alternate gene names: 220916746

Gene position: 1831509-1832477 (Clockwise)

Preceding gene: 220916744

Following gene: 220916747

Centisome position: 36.42

GC content: 72.86

Gene sequence:

>969_bases
ATGTTGCCGAGGACCTGCCGCCGTCTCGTCCCGCTGCTCTTGCTCGCGGTGGCTCCCGCGGTCGGCGCGCAGGAGATCCG
CGTGACGCTGCTCGGGACGGGGAGGCCCGCGCCGGAGATCGACCGGTTCGGCCCGAGCACGCTCGTGGAGGCCGGAGGGC
ACCGGCTGCTCTTCGACGCCGGACGCGGCGTGACGCAGCGGTTGTGGCAGCTCCGGATACCCCTTCGAGACGTGGACGCG
GTCTTCCTGACGCATCTCCACTCGGATCACGTGGTCGGCCTCCCCGACCTCTGGCTCACCGGCTGGCTGCCGACGCCGTT
CGGACGTCGCGCTGCGCCGCTGTCGCTGTGGGGGCCCGCGGGGACGGTCGACATGGTGGCCGCGCTCCGGAGGGCGTATG
CGTGGGACCTGCGCGCCCGCAGCGGGCACCAGCAGCTCCCGGAAGCGGGGACCACGATCCGTGCGCGCGACGTCAAGCAG
GGCGTCGTGTACGAACGCGACGGCGTGAAGGTCACCGCGTTCCTCGTCGACCACGGACCGCACCTCCGTCCCGCGCTCGG
GTACCGCGTCGATCACGCCGGGCGGTCCGTCGCCATCTCGGGGGACACGCGCCCGTGCGAGAATCTCGTCCGGTTCGCGG
CGGGCACCGACGTGCTCGTCCACGAGGTGGCTGCCGCGCGAAAGGAGCTCGTGGAGCGTTCCGCCGTGGTGCGCAGCATC
CTCGAGGTCCACACCTCGCCTGAGGACGCGGGCCGGGTCTTCACGCGCGTGAAGCCCAGGCTCGCGGTGTTCACGCACGT
CGCGCTGGTCACGACGGACCCGGACGTGCCGGCGCCCTCGGTCGCGGACATCATCGCCCGGACGCGCACGACCTACGCCG
GGCCGCTCGTCGTCGGCGAGGACCTCATGACGGTCGTCATCGGCGACGAGGTCGAGGTCCGCCACGCTCCGGAGGCGGGT
GCCCGCTGA

Upstream 100 bases:

>100_bases
ATACCGGCGAGCCACCGGCTCGCGCGGGTACGCGCACGCGCGACCTTCCGTCGTTACGTCGTCGTCCGGCCGCACGCGCT
GCGACCGGAGTGGAGGGTGC

Downstream 100 bases:

>100_bases
AGGCGCCGCCGTCGCGCTGACCTGCTGGGCTCACGTTCGCACCGTCGCGAAACTCTGCACCGTGTTGTGTTCCTCCGCAG
TGCGGGGCGCGAGGCCGATC

Product: Ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MLPRTCRRLVPLLLLAVAPAVGAQEIRVTLLGTGRPAPEIDRFGPSTLVEAGGHRLLFDAGRGVTQRLWQLRIPLRDVDA
VFLTHLHSDHVVGLPDLWLTGWLPTPFGRRAAPLSLWGPAGTVDMVAALRRAYAWDLRARSGHQQLPEAGTTIRARDVKQ
GVVYERDGVKVTAFLVDHGPHLRPALGYRVDHAGRSVAISGDTRPCENLVRFAAGTDVLVHEVAAARKELVERSAVVRSI
LEVHTSPEDAGRVFTRVKPRLAVFTHVALVTTDPDVPAPSVADIIARTRTTYAGPLVVGEDLMTVVIGDEVEVRHAPEAG
AR

Sequences:

>Translated_322_residues
MLPRTCRRLVPLLLLAVAPAVGAQEIRVTLLGTGRPAPEIDRFGPSTLVEAGGHRLLFDAGRGVTQRLWQLRIPLRDVDA
VFLTHLHSDHVVGLPDLWLTGWLPTPFGRRAAPLSLWGPAGTVDMVAALRRAYAWDLRARSGHQQLPEAGTTIRARDVKQ
GVVYERDGVKVTAFLVDHGPHLRPALGYRVDHAGRSVAISGDTRPCENLVRFAAGTDVLVHEVAAARKELVERSAVVRSI
LEVHTSPEDAGRVFTRVKPRLAVFTHVALVTTDPDVPAPSVADIIARTRTTYAGPLVVGEDLMTVVIGDEVEVRHAPEAG
AR
>Mature_322_residues
MLPRTCRRLVPLLLLAVAPAVGAQEIRVTLLGTGRPAPEIDRFGPSTLVEAGGHRLLFDAGRGVTQRLWQLRIPLRDVDA
VFLTHLHSDHVVGLPDLWLTGWLPTPFGRRAAPLSLWGPAGTVDMVAALRRAYAWDLRARSGHQQLPEAGTTIRARDVKQ
GVVYERDGVKVTAFLVDHGPHLRPALGYRVDHAGRSVAISGDTRPCENLVRFAAGTDVLVHEVAAARKELVERSAVVRSI
LEVHTSPEDAGRVFTRVKPRLAVFTHVALVTTDPDVPAPSVADIIARTRTTYAGPLVVGEDLMTVVIGDEVEVRHAPEAG
AR

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 34954; Mature: 34954

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPRTCRRLVPLLLLAVAPAVGAQEIRVTLLGTGRPAPEIDRFGPSTLVEAGGHRLLFDA
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHCCCHHHHHCCCCEEEEEC
GRGVTQRLWQLRIPLRDVDAVFLTHLHSDHVVGLPDLWLTGWLPTPFGRRAAPLSLWGPA
CCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCHHHCCCCCCCCCCCCCCCEECCCC
GTVDMVAALRRAYAWDLRARSGHQQLPEAGTTIRARDVKQGVVYERDGVKVTAFLVDHGP
CHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEHHHHCCCEEECCCCEEEEEEEECCC
HLRPALGYRVDHAGRSVAISGDTRPCENLVRFAAGTDVLVHEVAAARKELVERSAVVRSI
CCCHHHCCEEECCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LEVHTSPEDAGRVFTRVKPRLAVFTHVALVTTDPDVPAPSVADIIARTRTTYAGPLVVGE
HHHCCCCHHHHHHHHHCCCHHEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEECC
DLMTVVIGDEVEVRHAPEAGAR
CEEEEEECCCEEEEECCCCCCC
>Mature Secondary Structure
MLPRTCRRLVPLLLLAVAPAVGAQEIRVTLLGTGRPAPEIDRFGPSTLVEAGGHRLLFDA
CCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHCCCHHHHHCCCCEEEEEC
GRGVTQRLWQLRIPLRDVDAVFLTHLHSDHVVGLPDLWLTGWLPTPFGRRAAPLSLWGPA
CCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCHHHCCCCCCCCCCCCCCCEECCCC
GTVDMVAALRRAYAWDLRARSGHQQLPEAGTTIRARDVKQGVVYERDGVKVTAFLVDHGP
CHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEHHHHCCCEEECCCCEEEEEEEECCC
HLRPALGYRVDHAGRSVAISGDTRPCENLVRFAAGTDVLVHEVAAARKELVERSAVVRSI
CCCHHHCCEEECCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LEVHTSPEDAGRVFTRVKPRLAVFTHVALVTTDPDVPAPSVADIIARTRTTYAGPLVVGE
HHHCCCCHHHHHHHHHCCCHHEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEECC
DLMTVVIGDEVEVRHAPEAGAR
CEEEEEECCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]