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The map label for this gene is yhdR [H]

Identifier: 220916739

GI number: 220916739

Start: 1824924

End: 1826093

Strand: Direct

Name: yhdR [H]

Synonym: A2cp1_1633

Alternate gene names: 220916739

Gene position: 1824924-1826093 (Clockwise)

Preceding gene: 220916738

Following gene: 220916743

Centisome position: 36.29

GC content: 71.54

Gene sequence:

>1170_bases
ATGGCCATCGTGTCGCGCAGGGCGGCGGCGGCGGATCGGGCGTTCGAGGCGGTCAAGAGCTTCTACTTCAGCTCGCGGTA
CGGCGAACGGCGCGGGGATGCCACCATCGCCGACTTCACCTTCGGGAACCCGCACGAGATGCCGCTCGACGGCCTCGTCG
CGGCCATCCGCGAAGCCGCCGTCCCGCTCGACGAGAACTGGTTCGCCTACAAGTCCAGCGAGGAGGCGCCGCAGGCGTTC
CTGGCCGAGACCGTCGGCCGCGAGCTGGGGCTTCCGCTCGAGCCATCCGACGTGGCCCTCACCGCCGGAGCCTTCGGGGC
CATCTCGCTCGCCTTCCGCCTACTGCTCGACGCCCGCGACGAGGCCATCTTCAACGCGCCGGCCTGGTTCTGCTACGAGC
CGATGCTCCTTGCGGCCGACGCCGTGCCGCGGGAGGTGGCGCTTCGCGCGCCGCGCTTCGACCTCGACCTCGAGGCCATC
GAGGCGGCCATCGGTCCGAACACGCGCCTCGTGATCGTGAACACCCCGCACAACCCCACGGGCCGGATCTACGGGCGCGC
CGAGCTGGCGGGGCTGGCGGAGGTGCTGGAGCGCGCTTCGCGCCGGATCGGCCGCCGGGTCTTCCTCCTGTCCGATGAGC
CCTATCGGCGCATCCGCTTCGACGGCCGGGCCTTCACCAGCCCGGCGGCCGTGTACCCGTGGACGCTCGTCTCCTACAGC
TACGGCAAGGTCCTGCTGGCCCCGGGGCAGCGGCTCGGCTACCTGGCCCTCTCACCGCTGATGCCCGCCTCCGACCGTCA
GCAGCTGCGCGACGTCATGTTCGCGAGCCAGATGGCGCTGGGCTGGTGCTTCCCGAATGCCGTCATGCAGTACGCGGTAC
CGCAGCTGGAGCCCCTCTCCATCGACGTGACGGCGCTGGCCCGCCGGCGCGATGCGCTGAGCGAGGCGCTGGGCCGGGCC
GGCCACGGCGTCCTGCCGCCGGAGGGGACGTTCTACCTGTGGGCGCGGTGGTCGGGAGATCCCGTCCGCCAGTGGGAGGC
CCTGGCCGACGAAGGGGTCTTCGTCATGCCGGGCACGCTCATGAAGCAGCCGGACTACTTCCGGATCAGCCTGACCGCGT
CGGACGCGATGGTGGCGCAAGCGCTTCCATACCTGGCCCGGCGGGCGTGA

Upstream 100 bases:

>100_bases
GCCGCTCTTCGCGGACGTGCCGTCGGAGATGACCGAGGAGGAACAGTCGATCGCGCGTTCCGTGGCGGACGCGGGCCCGA
AGGCCTGAGGGCGCACGGCC

Downstream 100 bases:

>100_bases
GGACGCCGCCCGGCGGTCTATGGTGCGCGCACCAGCGCGACCACCGAAGGCGAGTAGGTGATGCAGCCGGCGCAGCACTT
CCCGGGTGCGCCCTCCACAG

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MAIVSRRAAAADRAFEAVKSFYFSSRYGERRGDATIADFTFGNPHEMPLDGLVAAIREAAVPLDENWFAYKSSEEAPQAF
LAETVGRELGLPLEPSDVALTAGAFGAISLAFRLLLDARDEAIFNAPAWFCYEPMLLAADAVPREVALRAPRFDLDLEAI
EAAIGPNTRLVIVNTPHNPTGRIYGRAELAGLAEVLERASRRIGRRVFLLSDEPYRRIRFDGRAFTSPAAVYPWTLVSYS
YGKVLLAPGQRLGYLALSPLMPASDRQQLRDVMFASQMALGWCFPNAVMQYAVPQLEPLSIDVTALARRRDALSEALGRA
GHGVLPPEGTFYLWARWSGDPVRQWEALADEGVFVMPGTLMKQPDYFRISLTASDAMVAQALPYLARRA

Sequences:

>Translated_389_residues
MAIVSRRAAAADRAFEAVKSFYFSSRYGERRGDATIADFTFGNPHEMPLDGLVAAIREAAVPLDENWFAYKSSEEAPQAF
LAETVGRELGLPLEPSDVALTAGAFGAISLAFRLLLDARDEAIFNAPAWFCYEPMLLAADAVPREVALRAPRFDLDLEAI
EAAIGPNTRLVIVNTPHNPTGRIYGRAELAGLAEVLERASRRIGRRVFLLSDEPYRRIRFDGRAFTSPAAVYPWTLVSYS
YGKVLLAPGQRLGYLALSPLMPASDRQQLRDVMFASQMALGWCFPNAVMQYAVPQLEPLSIDVTALARRRDALSEALGRA
GHGVLPPEGTFYLWARWSGDPVRQWEALADEGVFVMPGTLMKQPDYFRISLTASDAMVAQALPYLARRA
>Mature_388_residues
AIVSRRAAAADRAFEAVKSFYFSSRYGERRGDATIADFTFGNPHEMPLDGLVAAIREAAVPLDENWFAYKSSEEAPQAFL
AETVGRELGLPLEPSDVALTAGAFGAISLAFRLLLDARDEAIFNAPAWFCYEPMLLAADAVPREVALRAPRFDLDLEAIE
AAIGPNTRLVIVNTPHNPTGRIYGRAELAGLAEVLERASRRIGRRVFLLSDEPYRRIRFDGRAFTSPAAVYPWTLVSYSY
GKVLLAPGQRLGYLALSPLMPASDRQQLRDVMFASQMALGWCFPNAVMQYAVPQLEPLSIDVTALARRRDALSEALGRAG
HGVLPPEGTFYLWARWSGDPVRQWEALADEGVFVMPGTLMKQPDYFRISLTASDAMVAQALPYLARRA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=288, Percent_Identity=27.0833333333333, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI169881279, Length=288, Percent_Identity=27.0833333333333, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI56713256, Length=258, Percent_Identity=26.7441860465116, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI56713254, Length=172, Percent_Identity=30.8139534883721, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4507369, Length=320, Percent_Identity=26.25, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786816, Length=307, Percent_Identity=28.3387622149837, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=260, Percent_Identity=26.5384615384615, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=276, Percent_Identity=25.3623188405797, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=276, Percent_Identity=25.3623188405797, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17567663, Length=302, Percent_Identity=24.1721854304636, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=266, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573069, Length=278, Percent_Identity=29.4964028776978, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646114, Length=278, Percent_Identity=29.4964028776978, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI28573067, Length=278, Percent_Identity=29.4964028776978, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI28573065, Length=278, Percent_Identity=29.4964028776978, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI18859735, Length=313, Percent_Identity=23.0031948881789, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42892; Mature: 42760

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVSRRAAAADRAFEAVKSFYFSSRYGERRGDATIADFTFGNPHEMPLDGLVAAIREAA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHC
VPLDENWFAYKSSEEAPQAFLAETVGRELGLPLEPSDVALTAGAFGAISLAFRLLLDARD
CCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHCCC
EAIFNAPAWFCYEPMLLAADAVPREVALRAPRFDLDLEAIEAAIGPNTRLVIVNTPHNPT
CHHCCCCCHHHHCHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCC
GRIYGRAELAGLAEVLERASRRIGRRVFLLSDEPYRRIRFDGRAFTSPAAVYPWTLVSYS
CCEEEHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEC
YGKVLLAPGQRLGYLALSPLMPASDRQQLRDVMFASQMALGWCFPNAVMQYAVPQLEPLS
CCEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
IDVTALARRRDALSEALGRAGHGVLPPEGTFYLWARWSGDPVRQWEALADEGVFVMPGTL
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCEEEECCHH
MKQPDYFRISLTASDAMVAQALPYLARRA
HCCCCEEEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIVSRRAAAADRAFEAVKSFYFSSRYGERRGDATIADFTFGNPHEMPLDGLVAAIREAA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHC
VPLDENWFAYKSSEEAPQAFLAETVGRELGLPLEPSDVALTAGAFGAISLAFRLLLDARD
CCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHCCC
EAIFNAPAWFCYEPMLLAADAVPREVALRAPRFDLDLEAIEAAIGPNTRLVIVNTPHNPT
CHHCCCCCHHHHCHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCC
GRIYGRAELAGLAEVLERASRRIGRRVFLLSDEPYRRIRFDGRAFTSPAAVYPWTLVSYS
CCEEEHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEC
YGKVLLAPGQRLGYLALSPLMPASDRQQLRDVMFASQMALGWCFPNAVMQYAVPQLEPLS
CCEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
IDVTALARRRDALSEALGRAGHGVLPPEGTFYLWARWSGDPVRQWEALADEGVFVMPGTL
EHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCEEEECCHH
MKQPDYFRISLTASDAMVAQALPYLARRA
HCCCCEEEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]