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The map label for this gene is ygcA [C]

Identifier: 220916705

GI number: 220916705

Start: 1785657

End: 1786973

Strand: Direct

Name: ygcA [C]

Synonym: A2cp1_1599

Alternate gene names: 220916705

Gene position: 1785657-1786973 (Clockwise)

Preceding gene: 220916704

Following gene: 220916706

Centisome position: 35.5

GC content: 80.11

Gene sequence:

>1317_bases
GTGCGCATCCCGCTGACCATCGAGGCGCTCGCCCCCGGCGGCGAGGGGGTGGGCCGCCACGGCGAGCTGACCGCGTTCGT
GCCCTGGACCGCGCCCGGCGACCGGGTGCTCGCCGACGTCCCGCCGCCGCGCCCGGGGGCGGCCACCGCGCACGGTGCGC
TCGTCGAGCTCACCGCGCCCGGCGAGGCCCGGGTGGCCGCGCCCTGCCGCCACTTCGGCCCGGGCCCGTCGCCGGACGCC
GCCTGCGGCGGCTGCGAGTGGCTCCACGTCGCGTACCCGGCGCAGCTCGCCGCGAAGGAACGGTCGCTCCACGAGGCGCT
GCGGCGGATCGGCAAGCTCGAGCCGGGCAGCTACCCGGCGCGGCCCATCGTCCCCTCGCCCTCGCCCCTGCGCTACCGCG
CCCGCGCCAAGTTCCACCACGACCGCGCCGCCGGCCGGCTGGTGTTCTTCCGCCGGCGCTCCCACGAGCCGGTCCGGCTG
CGGGAGTGCCACCTGCTCTCGCCCGGGCTCGACGCGCTGCGCGAGGCGGTCGGGCCGGCGCTCGCCGCGGCGAGGCTGTC
GCCGCGCGAGGTGGCGCTGGAGTGGTCGGACGCCGCGGGGCGGGGCGCGGCGTGGCTGCTCCTGCCGGAGGTGACCGCGC
CGGTGCGCGCCCGCGCCGAGGCGCTCCTCCGGGACGTGCCCTCGCTCCAGGGCCTCGTGCTCCAGGCCGAGGGCGGGCAG
CCGGTGACCGCCGGCGACCCGGTGCTGCGGCACGCGCGCGCGCCCGGCCGGCCGGAGGCGGGGACGCAGCGCTCGCGGCC
GGACGTGTTCCAGCAGGCGAACCGCGGCGCGAACGCGCGGCTGGTGGAGACCGCGCTCGAGCTGCTCGCGCCCGCGGGCG
AGGACGTCCTCGAGCTGCACTGCGGCGCGGGGAACTTCACCGGGCCGCTCTCGGAGCAGGCCCGGAGCGTCTCCGCGGTG
GAGGTGCAGGGGCCGGCGCTCGACCTGGCCCGCGCCGACCTGGGCGGGCGGAACGTGCGCTTCTTCGCGGGCGACGCGCT
GGCGCTGGCGCGCGCCTTCGGCCGCGAGGCCGGCCCCGGGGCGCGGCGCTTCGGCGCGGCGCTGCTCGATCCGCCGCGCG
AGGGGGCGCGGGGGATCGGGCCCGCGCTCCGCGACCTGGGCGTCCCGCGGGCCGTCTACGTCTCCTGCGACCCGGCCACG
TTCGCGCGCGACCTGCGCGCCTGCGTGGAGGCCGGCTATCGGGTCGCGGCGGTGGTCCCGGTGGACATGTTCCCGCAGAC
GCACCACGTGGAGGGGGTGGCGCTGCTCGAGCGGTAG

Upstream 100 bases:

>100_bases
GAGGCGTTCGTCTCGCGGCTGCGCCGCGACCTCGACGAGACCTGAGCCCGGCCGGCGCCCGCCGGCTGAAGTTCGCGCCG
GGGCGTGTTATCCCCGGCGC

Downstream 100 bases:

>100_bases
CGCGCCGGTTGGGGGCGAGGCGGGGGGCCGCGCCCACCCACGGCTCCCGCCGTGACACGCTGGTGACACGCCCGGGGCAC
GCTCCCACCGGCCACCGGCC

Product: (uracil-5)-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRIPLTIEALAPGGEGVGRHGELTAFVPWTAPGDRVLADVPPPRPGAATAHGALVELTAPGEARVAAPCRHFGPGPSPDA
ACGGCEWLHVAYPAQLAAKERSLHEALRRIGKLEPGSYPARPIVPSPSPLRYRARAKFHHDRAAGRLVFFRRRSHEPVRL
RECHLLSPGLDALREAVGPALAAARLSPREVALEWSDAAGRGAAWLLLPEVTAPVRARAEALLRDVPSLQGLVLQAEGGQ
PVTAGDPVLRHARAPGRPEAGTQRSRPDVFQQANRGANARLVETALELLAPAGEDVLELHCGAGNFTGPLSEQARSVSAV
EVQGPALDLARADLGGRNVRFFAGDALALARAFGREAGPGARRFGAALLDPPREGARGIGPALRDLGVPRAVYVSCDPAT
FARDLRACVEAGYRVAAVVPVDMFPQTHHVEGVALLER

Sequences:

>Translated_438_residues
MRIPLTIEALAPGGEGVGRHGELTAFVPWTAPGDRVLADVPPPRPGAATAHGALVELTAPGEARVAAPCRHFGPGPSPDA
ACGGCEWLHVAYPAQLAAKERSLHEALRRIGKLEPGSYPARPIVPSPSPLRYRARAKFHHDRAAGRLVFFRRRSHEPVRL
RECHLLSPGLDALREAVGPALAAARLSPREVALEWSDAAGRGAAWLLLPEVTAPVRARAEALLRDVPSLQGLVLQAEGGQ
PVTAGDPVLRHARAPGRPEAGTQRSRPDVFQQANRGANARLVETALELLAPAGEDVLELHCGAGNFTGPLSEQARSVSAV
EVQGPALDLARADLGGRNVRFFAGDALALARAFGREAGPGARRFGAALLDPPREGARGIGPALRDLGVPRAVYVSCDPAT
FARDLRACVEAGYRVAAVVPVDMFPQTHHVEGVALLER
>Mature_438_residues
MRIPLTIEALAPGGEGVGRHGELTAFVPWTAPGDRVLADVPPPRPGAATAHGALVELTAPGEARVAAPCRHFGPGPSPDA
ACGGCEWLHVAYPAQLAAKERSLHEALRRIGKLEPGSYPARPIVPSPSPLRYRARAKFHHDRAAGRLVFFRRRSHEPVRL
RECHLLSPGLDALREAVGPALAAARLSPREVALEWSDAAGRGAAWLLLPEVTAPVRARAEALLRDVPSLQGLVLQAEGGQ
PVTAGDPVLRHARAPGRPEAGTQRSRPDVFQQANRGANARLVETALELLAPAGEDVLELHCGAGNFTGPLSEQARSVSAV
EVQGPALDLARADLGGRNVRFFAGDALALARAFGREAGPGARRFGAALLDPPREGARGIGPALRDLGVPRAVYVSCDPAT
FARDLRACVEAGYRVAAVVPVDMFPQTHHVEGVALLER

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Escherichia coli, GI1789148, Length=449, Percent_Identity=31.8485523385301, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790403, Length=369, Percent_Identity=26.2872628726287, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787083, Length=384, Percent_Identity=25.2604166666667, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24666579, Length=187, Percent_Identity=32.0855614973262, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280 [H]

Pfam domain/function: PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 46252; Mature: 46252

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIPLTIEALAPGGEGVGRHGELTAFVPWTAPGDRVLADVPPPRPGAATAHGALVELTAP
CCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEEEEECC
GEARVAAPCRHFGPGPSPDAACGGCEWLHVAYPAQLAAKERSLHEALRRIGKLEPGSYPA
CCCCEECCHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
RPIVPSPSPLRYRARAKFHHDRAAGRLVFFRRRSHEPVRLRECHLLSPGLDALREAVGPA
CCCCCCCCCCEEHHHHHHHHHHHCCEEEEEECCCCCCCEEHHEEECCCCHHHHHHHHHHH
LAAARLSPREVALEWSDAAGRGAAWLLLPEVTAPVRARAEALLRDVPSLQGLVLQAEGGQ
HHHHCCCCHHEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
PVTAGDPVLRHARAPGRPEAGTQRSRPDVFQQANRGANARLVETALELLAPAGEDVLELH
CCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEE
CGAGNFTGPLSEQARSVSAVEVQGPALDLARADLGGRNVRFFAGDALALARAFGREAGPG
CCCCCCCCCHHHHHHCCEEEEECCCCHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCC
ARRFGAALLDPPREGARGIGPALRDLGVPRAVYVSCDPATFARDLRACVEAGYRVAAVVP
HHHHCHHHCCCCCCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEEE
VDMFPQTHHVEGVALLER
HHCCCCCCCCCCEEEECC
>Mature Secondary Structure
MRIPLTIEALAPGGEGVGRHGELTAFVPWTAPGDRVLADVPPPRPGAATAHGALVELTAP
CCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEEEEECC
GEARVAAPCRHFGPGPSPDAACGGCEWLHVAYPAQLAAKERSLHEALRRIGKLEPGSYPA
CCCCEECCHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
RPIVPSPSPLRYRARAKFHHDRAAGRLVFFRRRSHEPVRLRECHLLSPGLDALREAVGPA
CCCCCCCCCCEEHHHHHHHHHHHCCEEEEEECCCCCCCEEHHEEECCCCHHHHHHHHHHH
LAAARLSPREVALEWSDAAGRGAAWLLLPEVTAPVRARAEALLRDVPSLQGLVLQAEGGQ
HHHHCCCCHHEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
PVTAGDPVLRHARAPGRPEAGTQRSRPDVFQQANRGANARLVETALELLAPAGEDVLELH
CCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEE
CGAGNFTGPLSEQARSVSAVEVQGPALDLARADLGGRNVRFFAGDALALARAFGREAGPG
CCCCCCCCCHHHHHHCCEEEEECCCCHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCC
ARRFGAALLDPPREGARGIGPALRDLGVPRAVYVSCDPATFARDLRACVEAGYRVAAVVP
HHHHCHHHCCCCCCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEEE
VDMFPQTHHVEGVALLER
HHCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA