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The map label for this gene is coaX

Identifier: 220916678

GI number: 220916678

Start: 1760054

End: 1760818

Strand: Direct

Name: coaX

Synonym: A2cp1_1572

Alternate gene names: 220916678

Gene position: 1760054-1760818 (Clockwise)

Preceding gene: 220916677

Following gene: 220916679

Centisome position: 35.0

GC content: 70.72

Gene sequence:

>765_bases
GTGCTCCTCGCCATCGACGTCGGCAACACGAACACGACCCTGGGCGTCTACGACGGCGCCGTGCTGCGCAGGCACTGGCG
CGTGGAGACGAGCCACACCCGCACCTACGACGAGTACGGGATCCTGCTGCGCCAGCTGTTCGCCTCGGCCGGCCTCGAGC
CGGCGCGGGTCTCGGCGGTGGTGATCGCGAGCGTGGTCCCGCCGCTCGCCTTCACCCTCGAGCAGATGTGCGTGCGGTAC
TTCGATCGCAAGCCCATGTTCGTCGGCCCGGGGATGAAGACCGGGATGCCCATCCTCTACGAGAACCCGCGCGAGGTGGG
CGCCGACCGGGTGGTGAACGCGGTGGCCGCGTACGAGCGCTGGCGCTGCGCCCTGGTGGTGGTGGACTTCGGCACCGCCA
CCACCTTCGACGTCATCTCCGCGAAGGGCGAGTACCTCGGCGGCGCGATCTGCCCCGGGATCGGCATCTCCATGGACGCC
CTCGCGCGCAGCGCGTCCAAGCTGCCGCGGGTGGAGTTCGCGAAGCCGCCCTCGGTCGTCGGCAAGAACACCGTCGCCTC
CATCCAGGCCGGTCTGGTGTACGGGTACGTCGGGATGGTGGACGGGATCTGCGCGCAGATCGCGGCCGAGCTGGCCACGC
CGCCCAAGGTGGTGGCGACCGGCGGGCTCGCGCCGCTCATCGCAGGCGTCTCCCGCAGCATCACCGAGGTGGACGAGCAC
CTCACGCTGGAGGGGCTGCGGATCCTCCACGAGCGCAACCGGTGA

Upstream 100 bases:

>100_bases
GACGTCCGCCTGCTGCGGCCCCGCTGACCCGCGCGCCGGCGCGCGCCCGCGGCGGCCGTGGAATTGACCCCGGACAGGCC
CGGAAGCTAGGCTCCGGCCC

Downstream 100 bases:

>100_bases
CCGCCCAGGCGACCCCAGCCGCGGCGCCGCGCGGTGCCGCCCCGGCGCGGAGCCTCCTCGACGAGGGCCTCGCCGCCTTC
GTCGCGCGCGACGTGGGCGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLLAIDVGNTNTTLGVYDGAVLRRHWRVETSHTRTYDEYGILLRQLFASAGLEPARVSAVVIASVVPPLAFTLEQMCVRY
FDRKPMFVGPGMKTGMPILYENPREVGADRVVNAVAAYERWRCALVVVDFGTATTFDVISAKGEYLGGAICPGIGISMDA
LARSASKLPRVEFAKPPSVVGKNTVASIQAGLVYGYVGMVDGICAQIAAELATPPKVVATGGLAPLIAGVSRSITEVDEH
LTLEGLRILHERNR

Sequences:

>Translated_254_residues
MLLAIDVGNTNTTLGVYDGAVLRRHWRVETSHTRTYDEYGILLRQLFASAGLEPARVSAVVIASVVPPLAFTLEQMCVRY
FDRKPMFVGPGMKTGMPILYENPREVGADRVVNAVAAYERWRCALVVVDFGTATTFDVISAKGEYLGGAICPGIGISMDA
LARSASKLPRVEFAKPPSVVGKNTVASIQAGLVYGYVGMVDGICAQIAAELATPPKVVATGGLAPLIAGVSRSITEVDEH
LTLEGLRILHERNR
>Mature_254_residues
MLLAIDVGNTNTTLGVYDGAVLRRHWRVETSHTRTYDEYGILLRQLFASAGLEPARVSAVVIASVVPPLAFTLEQMCVRY
FDRKPMFVGPGMKTGMPILYENPREVGADRVVNAVAAYERWRCALVVVDFGTATTFDVISAKGEYLGGAICPGIGISMDA
LARSASKLPRVEFAKPPSVVGKNTVASIQAGLVYGYVGMVDGICAQIAAELATPPKVVATGGLAPLIAGVSRSITEVDEH
LTLEGLRILHERNR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_ANAD2 (B8J561)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002491982.1
- ProteinModelPortal:   B8J561
- SMR:   B8J561
- GeneID:   7296330
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_1572
- HOGENOM:   HBG634537
- ProtClustDB:   PRK13321
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27247; Mature: 27247

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIDVGNTNTTLGVYDGAVLRRHWRVETSHTRTYDEYGILLRQLFASAGLEPARVSAV
CEEEEEECCCCCEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
VIASVVPPLAFTLEQMCVRYFDRKPMFVGPGMKTGMPILYENPREVGADRVVNAVAAYER
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHC
WRCALVVVDFGTATTFDVISAKGEYLGGAICPGIGISMDALARSASKLPRVEFAKPPSVV
CEEEEEEEECCCCCHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
GKNTVASIQAGLVYGYVGMVDGICAQIAAELATPPKVVATGGLAPLIAGVSRSITEVDEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHH
LTLEGLRILHERNR
HHHHHHHHHHHCCC
>Mature Secondary Structure
MLLAIDVGNTNTTLGVYDGAVLRRHWRVETSHTRTYDEYGILLRQLFASAGLEPARVSAV
CEEEEEECCCCCEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
VIASVVPPLAFTLEQMCVRYFDRKPMFVGPGMKTGMPILYENPREVGADRVVNAVAAYER
HHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHC
WRCALVVVDFGTATTFDVISAKGEYLGGAICPGIGISMDALARSASKLPRVEFAKPPSVV
CEEEEEEEECCCCCHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
GKNTVASIQAGLVYGYVGMVDGICAQIAAELATPPKVVATGGLAPLIAGVSRSITEVDEH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHH
LTLEGLRILHERNR
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA