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The map label for this gene is ppiD [H]

Identifier: 220916557

GI number: 220916557

Start: 1624363

End: 1625934

Strand: Reverse

Name: ppiD [H]

Synonym: A2cp1_1451

Alternate gene names: 220916557

Gene position: 1625934-1624363 (Counterclockwise)

Preceding gene: 220916562

Following gene: 220916556

Centisome position: 32.33

GC content: 73.79

Gene sequence:

>1572_bases
ATGCTCGATATCGTCCGGGCCAACAAGAAGGGCATTTTCTCCTGGCTCATCGTCCTCGGGATCGTGGTGGTGTTCGCCAT
CAACTTCGGTCCCGGTTCGCTGTCCAAGGGGGGCGCGGGCTGCGGCGGCGCCCCGGCCTACGCCGCCCGGGTCAACGGGA
AGAGCATCTCGGCCGCCGACTTCGAGCGGCAGTACGAGAACCTGCTCCGCTTCTACCAGCAGCAGGCCGGTGAGGGCTTC
ACCCGCGAGCTCGCGGCGCAGCTCGGCCTCGGGCGCCAGGCGCTGGGCGTGCTGGAGGATCGCGAGCTGGCGCTGCAGGA
GGCGCGGCGCCGCGGCGTGGTGGTGACCGACCGCGAGGTGTCCGAGGCGGTCCACCAGATGCCGGCGTTCCAGGAGAACG
GCCAGTTCCGCTACGAGACCTACCTCGAGGCGGTCCGCGCGAACTACGGCTCGCCCGGCAACTTCGAGGCGGCGGTCCGC
GACGACCTGCTCTACCAGAAGATCCTCGGCGCGCTCGTCGAGACCGTGAAGGTGCCCGCCACCGAGGTGCGCGCGCAGTG
GGCGGCCTCGGCCGACCGCGCCTCGCTGCAGTTCGTGCGGTTCCCGGTCGCCGCGGCGCAGGCCGAGGTGAAGGTGCCCG
ACGCGGAAGCGAAGGCGTTCGCGGACAAGGAGGGCGCGCGCGTCGAGGCGTTCTACAAGGAGAACGCCGATCGCTACGAC
CAGAGGGCCAAGGCCCACGTCCGGCACGTGCTGGCGCGCGTGGCGCCGGGCGCCTCCGCCGACGAGGAGGCGGCCGCGCG
GAAGAAGATCGACGAGGCGGCGGCACGGGTGAAGAAGGGCGAGGACTTCGCCAAGGTGGCTGCGGCGCTGTCCGACGACC
CGAACACCAAGGATCGGGGCGGCGACCTCGGCTTCGTCTCCGAGGGGCTCGCCGACGCCGCGTTCGCCAAGGCCGCGCTC
GCCCTGAAGGCCGGAGAGGTCTCGGAGCCGGTGCGCACCCCCGCCGGCTGGCACCTCATCCGCGCCGACGAGGTCGTCCC
CGCGCGCAAGGTGACGCTCGAGGCGGCACGCCTCGACATCGCCCGCGAGCTGCTGGCCCGCGACCGCGCGCAGGCGCTGG
CCCGCGAGAAGGCGCAGGCCGCGCTGGACGCGGCGCGCAAGGGCAAGGCGCTCGACGAGCTGTTCCCGCCCGCCGGCAAG
GGCAAGGTGACGCTGGGCGGCACCGCCCTCGCCGCCGAGGAGACCGGGCCGTTCGGCGCCGGCTCGCCGGTGGTGCCGCG
CGTCGGCGCCGCGCCGGAGCTGGCGCAGGCCGCGCTCTCCGCGAAGGCGGGCGAGGTGCTCCCGAAGGTCTTCGACACGC
CGAGCGGCCCGGTGATCGCCGTGGTCAAGCTGCGCGAGTCGCCGGATCCCGCGAGGTTCGAGGCGGAGCGCGCGGGCATC
GAGGCGCGGCTCCAGGGCATGAAGGCGGAGCAGGTGCGCCGCGCCTGGCTCGAGGAGCTGCGCGGCAAGGCGAAGATCGA
GGAGAACGTGGCGCTGCTGGGCGCGGCCCAGCCGGCTGCGCCGCAGCCCTGA

Upstream 100 bases:

>100_bases
AAACCCTTGCATTTTAGCCCTTGTTGACTAGGGTGTTCAACTTCGCGGCGCCCACCCCTTTCCAGGGCGTTCGTCTTACA
ACAACTCGGAGCATCGCTTC

Downstream 100 bases:

>100_bases
CGTGGCGCCCCGGCTCGTCCTCGCGTCGCAGAGCCCCCGCCGGCGCGAGCTGCTCGCGCAGCTCGGGCTCGCGCTGGAGA
TCCGCCCGGCCGACACCGAC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MLDIVRANKKGIFSWLIVLGIVVVFAINFGPGSLSKGGAGCGGAPAYAARVNGKSISAADFERQYENLLRFYQQQAGEGF
TRELAAQLGLGRQALGVLEDRELALQEARRRGVVVTDREVSEAVHQMPAFQENGQFRYETYLEAVRANYGSPGNFEAAVR
DDLLYQKILGALVETVKVPATEVRAQWAASADRASLQFVRFPVAAAQAEVKVPDAEAKAFADKEGARVEAFYKENADRYD
QRAKAHVRHVLARVAPGASADEEAAARKKIDEAAARVKKGEDFAKVAAALSDDPNTKDRGGDLGFVSEGLADAAFAKAAL
ALKAGEVSEPVRTPAGWHLIRADEVVPARKVTLEAARLDIARELLARDRAQALAREKAQAALDAARKGKALDELFPPAGK
GKVTLGGTALAAEETGPFGAGSPVVPRVGAAPELAQAALSAKAGEVLPKVFDTPSGPVIAVVKLRESPDPARFEAERAGI
EARLQGMKAEQVRRAWLEELRGKAKIEENVALLGAAQPAAPQP

Sequences:

>Translated_523_residues
MLDIVRANKKGIFSWLIVLGIVVVFAINFGPGSLSKGGAGCGGAPAYAARVNGKSISAADFERQYENLLRFYQQQAGEGF
TRELAAQLGLGRQALGVLEDRELALQEARRRGVVVTDREVSEAVHQMPAFQENGQFRYETYLEAVRANYGSPGNFEAAVR
DDLLYQKILGALVETVKVPATEVRAQWAASADRASLQFVRFPVAAAQAEVKVPDAEAKAFADKEGARVEAFYKENADRYD
QRAKAHVRHVLARVAPGASADEEAAARKKIDEAAARVKKGEDFAKVAAALSDDPNTKDRGGDLGFVSEGLADAAFAKAAL
ALKAGEVSEPVRTPAGWHLIRADEVVPARKVTLEAARLDIARELLARDRAQALAREKAQAALDAARKGKALDELFPPAGK
GKVTLGGTALAAEETGPFGAGSPVVPRVGAAPELAQAALSAKAGEVLPKVFDTPSGPVIAVVKLRESPDPARFEAERAGI
EARLQGMKAEQVRRAWLEELRGKAKIEENVALLGAAQPAAPQP
>Mature_523_residues
MLDIVRANKKGIFSWLIVLGIVVVFAINFGPGSLSKGGAGCGGAPAYAARVNGKSISAADFERQYENLLRFYQQQAGEGF
TRELAAQLGLGRQALGVLEDRELALQEARRRGVVVTDREVSEAVHQMPAFQENGQFRYETYLEAVRANYGSPGNFEAAVR
DDLLYQKILGALVETVKVPATEVRAQWAASADRASLQFVRFPVAAAQAEVKVPDAEAKAFADKEGARVEAFYKENADRYD
QRAKAHVRHVLARVAPGASADEEAAARKKIDEAAARVKKGEDFAKVAAALSDDPNTKDRGGDLGFVSEGLADAAFAKAAL
ALKAGEVSEPVRTPAGWHLIRADEVVPARKVTLEAARLDIARELLARDRAQALAREKAQAALDAARKGKALDELFPPAGK
GKVTLGGTALAAEETGPFGAGSPVVPRVGAAPELAQAALSAKAGEVLPKVFDTPSGPVIAVVKLRESPDPARFEAERAGI
EARLQGMKAEQVRRAWLEELRGKAKIEENVALLGAAQPAAPQP

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=415, Percent_Identity=24.8192771084337, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786238, Length=125, Percent_Identity=37.6, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 55662; Mature: 55662

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIVRANKKGIFSWLIVLGIVVVFAINFGPGSLSKGGAGCGGAPAYAARVNGKSISAAD
CCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHH
FERQYENLLRFYQQQAGEGFTRELAAQLGLGRQALGVLEDRELALQEARRRGVVVTDREV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHH
SEAVHQMPAFQENGQFRYETYLEAVRANYGSPGNFEAAVRDDLLYQKILGALVETVKVPA
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
TEVRAQWAASADRASLQFVRFPVAAAQAEVKVPDAEAKAFADKEGARVEAFYKENADRYD
HHHHHHHHCCCCHHHHHHHHHHHHHHHCEEECCCHHHHHHHCCCCCEEEHHHHHCHHHHH
QRAKAHVRHVLARVAPGASADEEAAARKKIDEAAARVKKGEDFAKVAAALSDDPNTKDRG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
GDLGFVSEGLADAAFAKAALALKAGEVSEPVRTPAGWHLIRADEVVPARKVTLEAARLDI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
ARELLARDRAQALAREKAQAALDAARKGKALDELFPPAGKGKVTLGGTALAAEETGPFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEECCCEEECCCCCCCCC
GSPVVPRVGAAPELAQAALSAKAGEVLPKVFDTPSGPVIAVVKLRESPDPARFEAERAGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHCH
EARLQGMKAEQVRRAWLEELRGKAKIEENVALLGAAQPAAPQP
HHHHHCCCHHHHHHHHHHHHCCCHHHHHCEEEEECCCCCCCCC
>Mature Secondary Structure
MLDIVRANKKGIFSWLIVLGIVVVFAINFGPGSLSKGGAGCGGAPAYAARVNGKSISAAD
CCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHH
FERQYENLLRFYQQQAGEGFTRELAAQLGLGRQALGVLEDRELALQEARRRGVVVTDREV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHH
SEAVHQMPAFQENGQFRYETYLEAVRANYGSPGNFEAAVRDDLLYQKILGALVETVKVPA
HHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCH
TEVRAQWAASADRASLQFVRFPVAAAQAEVKVPDAEAKAFADKEGARVEAFYKENADRYD
HHHHHHHHCCCCHHHHHHHHHHHHHHHCEEECCCHHHHHHHCCCCCEEEHHHHHCHHHHH
QRAKAHVRHVLARVAPGASADEEAAARKKIDEAAARVKKGEDFAKVAAALSDDPNTKDRG
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
GDLGFVSEGLADAAFAKAALALKAGEVSEPVRTPAGWHLIRADEVVPARKVTLEAARLDI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
ARELLARDRAQALAREKAQAALDAARKGKALDELFPPAGKGKVTLGGTALAAEETGPFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEECCCEEECCCCCCCCC
GSPVVPRVGAAPELAQAALSAKAGEVLPKVFDTPSGPVIAVVKLRESPDPARFEAERAGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHCH
EARLQGMKAEQVRRAWLEELRGKAKIEENVALLGAAQPAAPQP
HHHHHCCCHHHHHHHHHHHHCCCHHHHHCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA