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The map label for this gene is kamA [H]

Identifier: 220916508

GI number: 220916508

Start: 1567593

End: 1568840

Strand: Reverse

Name: kamA [H]

Synonym: A2cp1_1402

Alternate gene names: 220916508

Gene position: 1568840-1567593 (Counterclockwise)

Preceding gene: 220916518

Following gene: 220916505

Centisome position: 31.19

GC content: 70.03

Gene sequence:

>1248_bases
ATGGCGAATCTTCCGGTGATGGGCGACGTCGGCGGGGTGACCGAGGAGCTGGCCGGCGGCGGCCGGACGAACGGGGAGGC
GAAGGCCCCGGCGGTGCGGCACGAGGACGCGCCCCGCCCGGTGGCGAACGTGCTGTCCCGGTTCAAGCCCGGCCCGCGCT
CGATCTGGGCCGGCGTGCCCGACGCGCTCTGGAACGACTGGCACTGGCAGCAGCGCGAGCGGGTCATCCGGCTCGAGCAG
CTCGAGCGCGTCCTGCGCGTCACGCCCGAGGAGCGCGAGGCGGCGGTGAAGACCGAGGCCGAGTTCCACATGGGCATCAC
GCCGTACTACGCGGCGCTGATGGACCCCGAGGACCCGACCTGCCCCATCCGCCTCCAGTCGGTGCCGACGATGGGCGAGC
TCAACATCCTCGCCTCCGATCTCGAGGACCCGCTCGCGGAGGAGCGGGACATGCCGGTGCCCGGCATCACGCACCGCTAC
CCGGACCGAGTGCTGTTCTACACGACGCACAACTGCCCGGTGTACTGCCGCCACTGCACCCGCAAGCGGAAGGTCTCCGA
CCCGACCAGCGCCGCGGCCAAGCGGCAGATCGAGGAGTCGCTCGCGTACATCGCGCAGCACACCGAGATCCGCGACGTGG
TGATCTCCGGCGGCGACCCGCTGTCGCTCTCCGACGACCGGCTCGACCACATCCTCGGCCGGCTCCGGGCCATCCCGCAC
GTGGAGATCTTCCGGCTCGGAACGCGCAACCTCGTCACGCTGCCGCAGCGCGTGACCGACGACTTCGTGTACATGCTGCG
CCGGCACCACCCGGTCTACGTGAACACGCACTTCAACCATCCGAAGGAGTGCACCGCCGAGGCGTTCGAGGCGGCCCGCC
GCCTCGCCGACGCCGGCTGCGTCATCGGCAACCAGATGGTGCTGCTGAAGGGCGTGAACGACGATCCGGCGGTGGTGAAG
GAGCTGAACCACAAGCTCCTGCTCATGCGGATCCGGCCCTACTACATCTACCAGTGCGACCTGGCGCGCGGCATCAGCCA
CTTCCGCACGCCGGTCGAGGCCGGCATCCGCATCATCGAGGCGCTCCGCGGCCACACCTCCGGGCTGGCGGTGCCGCAGT
TCGTGGTGGACGCGCCGAACGGCGGCGGAAAGATCCCGGTGAACCCCGAGTACGTGGTCTCCCACGAGGGGAAGCGCTGG
GTGCTCCGCAACTTCGCCGGCAAGCAGTTCGAGTACGTCGAGCCGTAG

Upstream 100 bases:

>100_bases
TACACCGCCGGGGCGCGGTCGCAGATGTCAATGGCGGCCCTCTCTGTTAAGCAATGCGGGCAACGGGCCGCCGGACCGGG
CCTCCTGGAGCGAGCACGAC

Downstream 100 bases:

>100_bases
CCCGCGCCGTCAGTCGACGACCGCGATCGCCTCGATCTCCACGCGCGCGCCGCGGGGGAGCCCGGCCACCTGCACGGTGG
AGCGGGCCGGCGCCGGCGCG

Product: lysine 2,3-aminomutase YodO family protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MANLPVMGDVGGVTEELAGGGRTNGEAKAPAVRHEDAPRPVANVLSRFKPGPRSIWAGVPDALWNDWHWQQRERVIRLEQ
LERVLRVTPEEREAAVKTEAEFHMGITPYYAALMDPEDPTCPIRLQSVPTMGELNILASDLEDPLAEERDMPVPGITHRY
PDRVLFYTTHNCPVYCRHCTRKRKVSDPTSAAAKRQIEESLAYIAQHTEIRDVVISGGDPLSLSDDRLDHILGRLRAIPH
VEIFRLGTRNLVTLPQRVTDDFVYMLRRHHPVYVNTHFNHPKECTAEAFEAARRLADAGCVIGNQMVLLKGVNDDPAVVK
ELNHKLLLMRIRPYYIYQCDLARGISHFRTPVEAGIRIIEALRGHTSGLAVPQFVVDAPNGGGKIPVNPEYVVSHEGKRW
VLRNFAGKQFEYVEP

Sequences:

>Translated_415_residues
MANLPVMGDVGGVTEELAGGGRTNGEAKAPAVRHEDAPRPVANVLSRFKPGPRSIWAGVPDALWNDWHWQQRERVIRLEQ
LERVLRVTPEEREAAVKTEAEFHMGITPYYAALMDPEDPTCPIRLQSVPTMGELNILASDLEDPLAEERDMPVPGITHRY
PDRVLFYTTHNCPVYCRHCTRKRKVSDPTSAAAKRQIEESLAYIAQHTEIRDVVISGGDPLSLSDDRLDHILGRLRAIPH
VEIFRLGTRNLVTLPQRVTDDFVYMLRRHHPVYVNTHFNHPKECTAEAFEAARRLADAGCVIGNQMVLLKGVNDDPAVVK
ELNHKLLLMRIRPYYIYQCDLARGISHFRTPVEAGIRIIEALRGHTSGLAVPQFVVDAPNGGGKIPVNPEYVVSHEGKRW
VLRNFAGKQFEYVEP
>Mature_414_residues
ANLPVMGDVGGVTEELAGGGRTNGEAKAPAVRHEDAPRPVANVLSRFKPGPRSIWAGVPDALWNDWHWQQRERVIRLEQL
ERVLRVTPEEREAAVKTEAEFHMGITPYYAALMDPEDPTCPIRLQSVPTMGELNILASDLEDPLAEERDMPVPGITHRYP
DRVLFYTTHNCPVYCRHCTRKRKVSDPTSAAAKRQIEESLAYIAQHTEIRDVVISGGDPLSLSDDRLDHILGRLRAIPHV
EIFRLGTRNLVTLPQRVTDDFVYMLRRHHPVYVNTHFNHPKECTAEAFEAARRLADAGCVIGNQMVLLKGVNDDPAVVKE
LNHKLLLMRIRPYYIYQCDLARGISHFRTPVEAGIRIIEALRGHTSGLAVPQFVVDAPNGGGKIPVNPEYVVSHEGKRWV
LRNFAGKQFEYVEP

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=325, Percent_Identity=29.5384615384615, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 46747; Mature: 46616

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLPVMGDVGGVTEELAGGGRTNGEAKAPAVRHEDAPRPVANVLSRFKPGPRSIWAGVP
CCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCCC
DALWNDWHWQQRERVIRLEQLERVLRVTPEEREAAVKTEAEFHMGITPYYAALMDPEDPT
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCHHHHEEECCCCCC
CPIRLQSVPTMGELNILASDLEDPLAEERDMPVPGITHRYPDRVLFYTTHNCPVYCRHCT
CCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHH
RKRKVSDPTSAAAKRQIEESLAYIAQHTEIRDVVISGGDPLSLSDDRLDHILGRLRAIPH
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
VEIFRLGTRNLVTLPQRVTDDFVYMLRRHHPVYVNTHFNHPKECTAEAFEAARRLADAGC
EEEEEECCCCEEECCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCE
VIGNQMVLLKGVNDDPAVVKELNHKLLLMRIRPYYIYQCDLARGISHFRTPVEAGIRIIE
EECCCEEEEECCCCCHHHHHHCCCEEEEEEECCEEEEEEHHHHHHHHHCCHHHHHHHHHH
ALRGHTSGLAVPQFVVDAPNGGGKIPVNPEYVVSHEGKRWVLRNFAGKQFEYVEP
HHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCEECCCC
>Mature Secondary Structure 
ANLPVMGDVGGVTEELAGGGRTNGEAKAPAVRHEDAPRPVANVLSRFKPGPRSIWAGVP
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCCC
DALWNDWHWQQRERVIRLEQLERVLRVTPEEREAAVKTEAEFHMGITPYYAALMDPEDPT
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCHHHHEEECCCCCC
CPIRLQSVPTMGELNILASDLEDPLAEERDMPVPGITHRYPDRVLFYTTHNCPVYCRHCT
CCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHH
RKRKVSDPTSAAAKRQIEESLAYIAQHTEIRDVVISGGDPLSLSDDRLDHILGRLRAIPH
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
VEIFRLGTRNLVTLPQRVTDDFVYMLRRHHPVYVNTHFNHPKECTAEAFEAARRLADAGC
EEEEEECCCCEEECCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCE
VIGNQMVLLKGVNDDPAVVKELNHKLLLMRIRPYYIYQCDLARGISHFRTPVEAGIRIIE
EECCCEEEEECCCCCHHHHHHCCCEEEEEEECCEEEEEEHHHHHHHHHCCHHHHHHHHHH
ALRGHTSGLAVPQFVVDAPNGGGKIPVNPEYVVSHEGKRWVLRNFAGKQFEYVEP
HHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]