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The map label for this gene is dfrA [H]

Identifier: 220916431

GI number: 220916431

Start: 1472023

End: 1473045

Strand: Reverse

Name: dfrA [H]

Synonym: A2cp1_1325

Alternate gene names: 220916431

Gene position: 1473045-1472023 (Counterclockwise)

Preceding gene: 220916432

Following gene: 220916429

Centisome position: 29.29

GC content: 75.86

Gene sequence:

>1023_bases
GTGAACCTGCTCGTCACCGGCGGCACCGGCTTCCTCGGCGCCGCGCTCGTCCCGCTGCTCGCCCGGGCCGGCCACCGACT
GCGGCTGCTGCAGCGCTCGGCGGCGCCGGAGGCGGAGGCGCTCGGCGCCGACGTGCGCCGGGCCGGGCTCGAGGACGCCG
AGGCGGTCCGGGCCGCGCTCGACGGGGTGGACGCGGTGTTCCACCTGGCCGGCCAGGTGGACTTCGATCCCGCCGAGCCC
GCGCGCCTGTACGAGCTGCACGTGCAGGGCACCCGGCGGCTCCTCGAGGCGTGCGTCGCCGCGGGCGTGCGGCGCGTGAT
CCTCGCCTCCACCTCGGGCACCATCGCGGTCTCGAAGGAGGAGCGGGTCGCCACCGAGGCCGACCCCTACCCCATCGCCG
CGGTGGCGGGCTGGCCCTACTACCTCTCCAAGATCTTCCAGGAGAAGGCGGCGCTGCGGATCCACCGCGACACCGGCCTG
CCGGTGGTGGTGCTGAACCCGTCGCTGCTGCTCGGACCGGGGGACGCCCGCCTCTCCTCCACCGACGTGGTGTTCAAGTT
CCTGGAGCGGCGCATCCCGGCCATGCCCACCGGCGGCCTCTCCTTCGTGGACGTGCGCGACGCGGCGCGCGCGTTCGCGG
CGGCGCTGGAGCGCGGGCGGCCCGGCGAGCGCTACCTGCTCGGCGGCGCGAACCTGAGCTTCCGGGACTTCTTCGGCCGG
CTGGAGCGGCTCTCGGGCGTGGCGGCGCCGCGGGTGGCGCTGCCCGGCGGCCTGAACGTCGCCGGCGCGCGGCTTCTGGA
GAAGCTCTCCGGGTGGCGCGGCGCCGAGGCGCCCATCGACGCGCCGTCGGTCGAGATGGGCGAGCACTTCTGGTACTGCG
ACTCGCGCAAGGCGGAGGAGGCGCTCGGGTTCTCGGCGCGCGATCCGCAGGAGACGCTGTTCGAGACCGTCCGCTGGCTG
GAGCAGCACGTGCGCGCGCGCAACGCGCCGGAGACCGTGGCGGAGCTGGTCCGCGGGCGGTGA

Upstream 100 bases:

>100_bases
CTGCGCCCGCCGCGCGCGCGGGGACGCCCGCGCCCGCCGAGCCCGCCGCCCCCGCCGCCGGCCCGGCGCCACGCCACCAC
CCCGGCCGACCGGAGGACGC

Downstream 100 bases:

>100_bases
TCGCGCGCGCCGCGCGCGTGCTACATCGTGCCGCCGCTCACGTCGCGCACCTTGCGGATGGCGGCCACTCCGCAGCGCTC
GCCGCAGGCGGCGCAGATCT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNLLVTGGTGFLGAALVPLLARAGHRLRLLQRSAAPEAEALGADVRRAGLEDAEAVRAALDGVDAVFHLAGQVDFDPAEP
ARLYELHVQGTRRLLEACVAAGVRRVILASTSGTIAVSKEERVATEADPYPIAAVAGWPYYLSKIFQEKAALRIHRDTGL
PVVVLNPSLLLGPGDARLSSTDVVFKFLERRIPAMPTGGLSFVDVRDAARAFAAALERGRPGERYLLGGANLSFRDFFGR
LERLSGVAAPRVALPGGLNVAGARLLEKLSGWRGAEAPIDAPSVEMGEHFWYCDSRKAEEALGFSARDPQETLFETVRWL
EQHVRARNAPETVAELVRGR

Sequences:

>Translated_340_residues
MNLLVTGGTGFLGAALVPLLARAGHRLRLLQRSAAPEAEALGADVRRAGLEDAEAVRAALDGVDAVFHLAGQVDFDPAEP
ARLYELHVQGTRRLLEACVAAGVRRVILASTSGTIAVSKEERVATEADPYPIAAVAGWPYYLSKIFQEKAALRIHRDTGL
PVVVLNPSLLLGPGDARLSSTDVVFKFLERRIPAMPTGGLSFVDVRDAARAFAAALERGRPGERYLLGGANLSFRDFFGR
LERLSGVAAPRVALPGGLNVAGARLLEKLSGWRGAEAPIDAPSVEMGEHFWYCDSRKAEEALGFSARDPQETLFETVRWL
EQHVRARNAPETVAELVRGR
>Mature_340_residues
MNLLVTGGTGFLGAALVPLLARAGHRLRLLQRSAAPEAEALGADVRRAGLEDAEAVRAALDGVDAVFHLAGQVDFDPAEP
ARLYELHVQGTRRLLEACVAAGVRRVILASTSGTIAVSKEERVATEADPYPIAAVAGWPYYLSKIFQEKAALRIHRDTGL
PVVVLNPSLLLGPGDARLSSTDVVFKFLERRIPAMPTGGLSFVDVRDAARAFAAALERGRPGERYLLGGANLSFRDFFGR
LERLSGVAAPRVALPGGLNVAGARLLEKLSGWRGAEAPIDAPSVEMGEHFWYCDSRKAEEALGFSARDPQETLFETVRWL
EQHVRARNAPETVAELVRGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71987463, Length=336, Percent_Identity=27.6785714285714, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 36645; Mature: 36645

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLVTGGTGFLGAALVPLLARAGHRLRLLQRSAAPEAEALGADVRRAGLEDAEAVRAAL
CCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
DGVDAVFHLAGQVDFDPAEPARLYELHVQGTRRLLEACVAAGVRRVILASTSGTIAVSKE
HHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCH
ERVATEADPYPIAAVAGWPYYLSKIFQEKAALRIHRDTGLPVVVLNPSLLLGPGDARLSS
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHHEEEECCCCCEEEEECCCEEECCCCCCCCH
TDVVFKFLERRIPAMPTGGLSFVDVRDAARAFAAALERGRPGERYLLGGANLSFRDFFGR
HHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
LERLSGVAAPRVALPGGLNVAGARLLEKLSGWRGAEAPIDAPSVEMGEHFWYCDSRKAEE
HHHHHCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCHHH
ALGFSARDPQETLFETVRWLEQHVRARNAPETVAELVRGR
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MNLLVTGGTGFLGAALVPLLARAGHRLRLLQRSAAPEAEALGADVRRAGLEDAEAVRAAL
CCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
DGVDAVFHLAGQVDFDPAEPARLYELHVQGTRRLLEACVAAGVRRVILASTSGTIAVSKE
HHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCH
ERVATEADPYPIAAVAGWPYYLSKIFQEKAALRIHRDTGLPVVVLNPSLLLGPGDARLSS
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHHEEEECCCCCEEEEECCCEEECCCCCCCCH
TDVVFKFLERRIPAMPTGGLSFVDVRDAARAFAAALERGRPGERYLLGGANLSFRDFFGR
HHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHH
LERLSGVAAPRVALPGGLNVAGARLLEKLSGWRGAEAPIDAPSVEMGEHFWYCDSRKAEE
HHHHHCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCHHH
ALGFSARDPQETLFETVRWLEQHVRARNAPETVAELVRGR
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]