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The map label for this gene is udg [H]

Identifier: 220916292

GI number: 220916292

Start: 1327745

End: 1329058

Strand: Reverse

Name: udg [H]

Synonym: A2cp1_1185

Alternate gene names: 220916292

Gene position: 1329058-1327745 (Counterclockwise)

Preceding gene: 220916293

Following gene: 220916291

Centisome position: 26.43

GC content: 72.75

Gene sequence:

>1314_bases
ATGCGGATCGCGGTGGTGGGCGCGGGGTACGTGGGGCTGGTCACCGGGACGTGCCTCGCCGAGTCCGGCAACGACGTCAG
CTGCGTGGACACCGACGCCGGGAAGATCGAGCGGCTCCAGCGCGGCGAGGTCCCGATCTACGAGCCGGGGCTGGAGGAGC
TGGTCCGGCGCAACCAGCGGGAGGGGCGGCTCCGCTTCGGCACCGACCTGGCGCAGGCGGTGGGCCGGGCCAAGGTGGTG
TTCCTGGCGGTGGGCACGCCGGAGGGCGAGGACGGCGACGCCGAGCTGCGCCACGTCATCGAGGCCGCCGAGGAGGTGGC
GCGCGCGGTGAAGCACTACACCGTGGTCGCGACCAAGAGCACGGTGCCCGTCGGGACCGCCGGGCGCATCCAGGAGATCA
TGGGCCGCCGCGCCCGCTTCGAGGTGGACGTGGTCTCGAACCCCGAGTTCCTGAAGGAGGGGGCGGCGCTGGAGGACTTC
CAGCGGCCCGACCGCGTGGTGGTGGGCGCCGGCAGCGACCGGGCCCGGCGGATCATGCGCGAGCTGTACGCCCCGTTCGT
GCGGACCGAGCGGCCCATCCTGTTCATGGAGCCGCGCTCGGCCGAGATGGTGAAGTACGCGGCGAACGCGATGCTCGCGA
CCCGCATCTCGTTCATGAACGACATCGCGCTGCTCTGCGAGAAGGTGGGCGCGGACGCCGAGCAGGTCCGGCGCGGCGTG
GGCGCGGACACGCGCATCGGCTACCCGTTCCTGTTCCCGGGGATCGGCTACGGCGGCTCCTGCTTCCCGAAGGACGTGAA
GGCGCTGCTCGCCACCGGCCGGCGGCATGGGGTGGACCTCGACCTGCTGCGCGCCGTGGAGAAGACCAACGAGCGCCAGA
AGCGCCACCTGCTGTCGCGCGCGGTGCGGCACTTCGGCGACCTCGCCGGCAGGGTGTTCGGCGTGTGGGGGCTCGCGTTC
AAGCCGCGCACCGACGACATGCGCGAGGCGCCCTCGGTCGAGGTCATCGAGGGGCTGCTGGGCAAGGGCGCGCGGGTGCA
GGCGTACGATCCGGTGGCGATGGAGCGCGCCCGGCGGCGCTTCGGCGAGCGGGTGACGTTCGCGCCCGGGCCGTACGAGG
CGCTGGAGGGGGCCGACGCGCTGTTCGTGGTCACCGAGTGGAGCGAGTTCCGCAACCCGGACTTCGACCGCATGAAGGCG
CTGCTCCGCGCGCCGGTGGTGTTCGACGGGCGCAACGTGTTCGACCCGGAGGAGATGCGCGAACAGGGGTTCAGCTACTT
CTGCGTCGGCAGGACGGCGGCCGGCGCGCGCTGA

Upstream 100 bases:

>100_bases
GTGCGCGAGGCGCGCGAGCGCGCGGCGCGGCGCCGGGCGCCGGCGCGCCGGCGCGCGCGGGTGGCGCAGGAGGATCCGGG
CTAGCGGACGAGGGGGATGG

Downstream 100 bases:

>100_bases
CGCCCCACCCCACCCGGACCCACCGCCGCCGTGGCAGGCCCGCCGGCGGGGCCCCATCTTCCGGTGGAGGCCGCGACGGA
GGCGCCCATGGACGGCGATC

Product: nucleotide sugar dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MRIAVVGAGYVGLVTGTCLAESGNDVSCVDTDAGKIERLQRGEVPIYEPGLEELVRRNQREGRLRFGTDLAQAVGRAKVV
FLAVGTPEGEDGDAELRHVIEAAEEVARAVKHYTVVATKSTVPVGTAGRIQEIMGRRARFEVDVVSNPEFLKEGAALEDF
QRPDRVVVGAGSDRARRIMRELYAPFVRTERPILFMEPRSAEMVKYAANAMLATRISFMNDIALLCEKVGADAEQVRRGV
GADTRIGYPFLFPGIGYGGSCFPKDVKALLATGRRHGVDLDLLRAVEKTNERQKRHLLSRAVRHFGDLAGRVFGVWGLAF
KPRTDDMREAPSVEVIEGLLGKGARVQAYDPVAMERARRRFGERVTFAPGPYEALEGADALFVVTEWSEFRNPDFDRMKA
LLRAPVVFDGRNVFDPEEMREQGFSYFCVGRTAAGAR

Sequences:

>Translated_437_residues
MRIAVVGAGYVGLVTGTCLAESGNDVSCVDTDAGKIERLQRGEVPIYEPGLEELVRRNQREGRLRFGTDLAQAVGRAKVV
FLAVGTPEGEDGDAELRHVIEAAEEVARAVKHYTVVATKSTVPVGTAGRIQEIMGRRARFEVDVVSNPEFLKEGAALEDF
QRPDRVVVGAGSDRARRIMRELYAPFVRTERPILFMEPRSAEMVKYAANAMLATRISFMNDIALLCEKVGADAEQVRRGV
GADTRIGYPFLFPGIGYGGSCFPKDVKALLATGRRHGVDLDLLRAVEKTNERQKRHLLSRAVRHFGDLAGRVFGVWGLAF
KPRTDDMREAPSVEVIEGLLGKGARVQAYDPVAMERARRRFGERVTFAPGPYEALEGADALFVVTEWSEFRNPDFDRMKA
LLRAPVVFDGRNVFDPEEMREQGFSYFCVGRTAAGAR
>Mature_437_residues
MRIAVVGAGYVGLVTGTCLAESGNDVSCVDTDAGKIERLQRGEVPIYEPGLEELVRRNQREGRLRFGTDLAQAVGRAKVV
FLAVGTPEGEDGDAELRHVIEAAEEVARAVKHYTVVATKSTVPVGTAGRIQEIMGRRARFEVDVVSNPEFLKEGAALEDF
QRPDRVVVGAGSDRARRIMRELYAPFVRTERPILFMEPRSAEMVKYAANAMLATRISFMNDIALLCEKVGADAEQVRRGV
GADTRIGYPFLFPGIGYGGSCFPKDVKALLATGRRHGVDLDLLRAVEKTNERQKRHLLSRAVRHFGDLAGRVFGVWGLAF
KPRTDDMREAPSVEVIEGLLGKGARVQAYDPVAMERARRRFGERVTFAPGPYEALEGADALFVVTEWSEFRNPDFDRMKA
LLRAPVVFDGRNVFDPEEMREQGFSYFCVGRTAAGAR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=471, Percent_Identity=34.6072186836518, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI296040438, Length=370, Percent_Identity=34.5945945945946, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI296040443, Length=322, Percent_Identity=35.7142857142857, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1788340, Length=358, Percent_Identity=29.608938547486, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI48994968, Length=411, Percent_Identity=26.0340632603406, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=464, Percent_Identity=33.6206896551724, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI17136908, Length=465, Percent_Identity=33.1182795698925, Blast_Score=256, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48285; Mature: 48285

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVVGAGYVGLVTGTCLAESGNDVSCVDTDAGKIERLQRGEVPIYEPGLEELVRRNQR
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHCCCC
EGRLRFGTDLAQAVGRAKVVFLAVGTPEGEDGDAELRHVIEAAEEVARAVKHYTVVATKS
CCCEEECCHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECC
TVPVGTAGRIQEIMGRRARFEVDVVSNPEFLKEGAALEDFQRPDRVVVGAGSDRARRIMR
CCCCCCHHHHHHHHCCHHEEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHHHHHHH
ELYAPFVRTERPILFMEPRSAEMVKYAANAMLATRISFMNDIALLCEKVGADAEQVRRGV
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GADTRIGYPFLFPGIGYGGSCFPKDVKALLATGRRHGVDLDLLRAVEKTNERQKRHLLSR
CCCCCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVRHFGDLAGRVFGVWGLAFKPRTDDMREAPSVEVIEGLLGKGARVQAYDPVAMERARRR
HHHHHHHHHHHHHHHHCCEECCCCCHHHHCCCHHHHHHHHCCCCEEEECCHHHHHHHHHH
FGERVTFAPGPYEALEGADALFVVTEWSEFRNPDFDRMKALLRAPVVFDGRNVFDPEEMR
HCCEEECCCCCHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHCCCEECCCCCCCHHHHH
EQGFSYFCVGRTAAGAR
HCCCCEEEEECCCCCCC
>Mature Secondary Structure
MRIAVVGAGYVGLVTGTCLAESGNDVSCVDTDAGKIERLQRGEVPIYEPGLEELVRRNQR
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHCCCC
EGRLRFGTDLAQAVGRAKVVFLAVGTPEGEDGDAELRHVIEAAEEVARAVKHYTVVATKS
CCCEEECCHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECC
TVPVGTAGRIQEIMGRRARFEVDVVSNPEFLKEGAALEDFQRPDRVVVGAGSDRARRIMR
CCCCCCHHHHHHHHCCHHEEEEEECCCHHHHHCCCCHHHHCCCCEEEEECCCHHHHHHHH
ELYAPFVRTERPILFMEPRSAEMVKYAANAMLATRISFMNDIALLCEKVGADAEQVRRGV
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
GADTRIGYPFLFPGIGYGGSCFPKDVKALLATGRRHGVDLDLLRAVEKTNERQKRHLLSR
CCCCCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVRHFGDLAGRVFGVWGLAFKPRTDDMREAPSVEVIEGLLGKGARVQAYDPVAMERARRR
HHHHHHHHHHHHHHHHCCEECCCCCHHHHCCCHHHHHHHHCCCCEEEECCHHHHHHHHHH
FGERVTFAPGPYEALEGADALFVVTEWSEFRNPDFDRMKALLRAPVVFDGRNVFDPEEMR
HCCEEECCCCCHHHHCCCCEEEEEECCHHHCCCCHHHHHHHHHCCCEECCCCCCCHHHHH
EQGFSYFCVGRTAAGAR
HCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]