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The map label for this gene is hhoB [H]

Identifier: 220916018

GI number: 220916018

Start: 1023754

End: 1024659

Strand: Reverse

Name: hhoB [H]

Synonym: A2cp1_0904

Alternate gene names: 220916018

Gene position: 1024659-1023754 (Counterclockwise)

Preceding gene: 220916019

Following gene: 220916017

Centisome position: 20.37

GC content: 79.58

Gene sequence:

>906_bases
GTGACCGGGCTGCAGGCGCTCTCGCGCGACGTCGCCGACCTCGTGGCCCGCGCCGCCCCGGCGGTGGTGGGCGTGGAGCA
GGGCGGCGGCCAGGGCTCCGGCGTCGTGATCGCGCCGGACGGCTGGGTGCTCACCAACGCGCACGTCGCGCGCGGACGCG
GCCCGGTCCGCGTCCGGCTCTCCGGCGCGCGGGTGGTGGCGGCGGAGCGCGCCGGCGGCGACGACCGCACCGACGTGGCG
GTGCTGCGGGTGGACGCGCGCGACCTCCCCTCCCTGGCGCTCTCCGAGCGGCGACTCTCGGTCGGAGAGCTGGTGGTGGC
CATCGGCAACCCGCTCGGCTTCGAGCGCTCGGTCACCCTGGGCGTGGTCTCGGCGCTGCACCGCAACCTGGCGGCGCCGC
GCGGGGCGGTGCTGGAGGGGCTGGTCCAGACCGACGCCTCGATCAACCCGGGCAACTCGGGCGGACCGCTGCTCGACGCC
GGCGGCGCGGTGGTCGGGCTCAGCACCGCCATGCTCCCCTGGGCGCACGGGATCGGCTTCGCGGTGCCGGCGCACACGGC
GGCGTGGGTGGCCTCGGTGCTGATGCGCGAGGGCGAGGTGCGCCGCCCGTTCCTCGGGATCGCGGCGCGCGGCGAGGACC
TCGACGCGCGCGACGCGGCGCTCGCCGGCCACGGGCGCGGCGTGCGGGTGCTCGAGGTGGTCGAGGGATCGCCGGCCGGC
CGCGCCGCCCTCCGGCCGGGCGACCTGCTCGTCGCGGCGAGCGGCAGCCCGGTGCAGACGCTGGACGACCTGCAGCGCGT
GCTGGTGCTGGCCCGGGCGGGCGAGATCGACCTGGCGGTCCTGCGCGCCGGCCGCCCGCTCCGGCTCGCCATCCGGCCCG
ACCCGCCGCGCGCCGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
TCTCGGAGGACCGGATCGGCCAGGCGGTGACGCTGCGCGTGCTGCGCGCGGGCGAGGTGCGCGACGTCGCGGTCACCGTG
GGCGCGCGCGGGAGGCGGGC

Downstream 100 bases:

>100_bases
GGGTCCGTGGCGACACCGACGTCGCGCCCCACCGGCGATCGGGGCGTGACGCTGGCGGCGTGGCGTGGTGAACTGGGAGG
CGATGCGCTCCTGGCTCGAC

Product: peptidase S1 and S6 chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTGLQALSRDVADLVARAAPAVVGVEQGGGQGSGVVIAPDGWVLTNAHVARGRGPVRVRLSGARVVAAERAGGDDRTDVA
VLRVDARDLPSLALSERRLSVGELVVAIGNPLGFERSVTLGVVSALHRNLAAPRGAVLEGLVQTDASINPGNSGGPLLDA
GGAVVGLSTAMLPWAHGIGFAVPAHTAAWVASVLMREGEVRRPFLGIAARGEDLDARDAALAGHGRGVRVLEVVEGSPAG
RAALRPGDLLVAASGSPVQTLDDLQRVLVLARAGEIDLAVLRAGRPLRLAIRPDPPRAAAA

Sequences:

>Translated_301_residues
MTGLQALSRDVADLVARAAPAVVGVEQGGGQGSGVVIAPDGWVLTNAHVARGRGPVRVRLSGARVVAAERAGGDDRTDVA
VLRVDARDLPSLALSERRLSVGELVVAIGNPLGFERSVTLGVVSALHRNLAAPRGAVLEGLVQTDASINPGNSGGPLLDA
GGAVVGLSTAMLPWAHGIGFAVPAHTAAWVASVLMREGEVRRPFLGIAARGEDLDARDAALAGHGRGVRVLEVVEGSPAG
RAALRPGDLLVAASGSPVQTLDDLQRVLVLARAGEIDLAVLRAGRPLRLAIRPDPPRAAAA
>Mature_300_residues
TGLQALSRDVADLVARAAPAVVGVEQGGGQGSGVVIAPDGWVLTNAHVARGRGPVRVRLSGARVVAAERAGGDDRTDVAV
LRVDARDLPSLALSERRLSVGELVVAIGNPLGFERSVTLGVVSALHRNLAAPRGAVLEGLVQTDASINPGNSGGPLLDAG
GAVVGLSTAMLPWAHGIGFAVPAHTAAWVASVLMREGEVRRPFLGIAARGEDLDARDAALAGHGRGVRVLEVVEGSPAGR
AALRPGDLLVAASGSPVQTLDDLQRVLVLARAGEIDLAVLRAGRPLRLAIRPDPPRAAAA

Specific function: A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=310, Percent_Identity=29.0322580645161, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI22129776, Length=313, Percent_Identity=30.6709265175719, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI24308541, Length=311, Percent_Identity=31.1897106109325, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI7019477, Length=313, Percent_Identity=32.9073482428115, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1789629, Length=272, Percent_Identity=37.1323529411765, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786356, Length=269, Percent_Identity=34.2007434944238, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789630, Length=304, Percent_Identity=33.2236842105263, Blast_Score=137, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24646839, Length=336, Percent_Identity=30.6547619047619, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 30615; Mature: 30483

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLQALSRDVADLVARAAPAVVGVEQGGGQGSGVVIAPDGWVLTNAHVARGRGPVRVRL
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCEEEECCCCCCCCCCEEEEE
SGARVVAAERAGGDDRTDVAVLRVDARDLPSLALSERRLSVGELVVAIGNPLGFERSVTL
CCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHCCCCHHEEEEEECCCCCCCCHHHH
GVVSALHRNLAAPRGAVLEGLVQTDASINPGNSGGPLLDAGGAVVGLSTAMLPWAHGIGF
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEHHHHHHHHHCCCCC
AVPAHTAAWVASVLMREGEVRRPFLGIAARGEDLDARDAALAGHGRGVRVLEVVEGSPAG
CCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHCCCCCCEEEEEEECCCCCC
RAALRPGDLLVAASGSPVQTLDDLQRVLVLARAGEIDLAVLRAGRPLRLAIRPDPPRAAA
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCC
A
C
>Mature Secondary Structure 
TGLQALSRDVADLVARAAPAVVGVEQGGGQGSGVVIAPDGWVLTNAHVARGRGPVRVRL
CCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEECCCCEEEECCCCCCCCCCEEEEE
SGARVVAAERAGGDDRTDVAVLRVDARDLPSLALSERRLSVGELVVAIGNPLGFERSVTL
CCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHHHCCCCHHEEEEEECCCCCCCCHHHH
GVVSALHRNLAAPRGAVLEGLVQTDASINPGNSGGPLLDAGGAVVGLSTAMLPWAHGIGF
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEHHHHHHHHHCCCCC
AVPAHTAAWVASVLMREGEVRRPFLGIAARGEDLDARDAALAGHGRGVRVLEVVEGSPAG
CCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHCCCCCCEEEEEEECCCCCC
RAALRPGDLLVAASGSPVQTLDDLQRVLVLARAGEIDLAVLRAGRPLRLAIRPDPPRAAA
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]